New pHealth approach to monitoring of seniors and handicapped people Jiri Chod, Czech Technical University in Prague Jaroslav Jansa, Immobiliser Central Europe, Ltd. Karel Zvolsky, COMINFO, Inc. Ivo Vaněk, National Noise Observatory Marek Semerád, Township Cerhenice

What is pHealth ? »pHealth« is use of Personal Health Systems (PHS) for Remote Patient Monitoring (RPM) – evaluates individual patients vital signs on daily basis and provides diagnostic information that can be transmitted to health care professionals for monitoring or early diagnosis purposes (“EC definition”)

Goals of pHealth  Conceptual transition of health care provisioning from hospital to domestic environment  Deployment of IT personal medical systems, the so- called PHS (Personal Health System)  Enabling medical professionals to monitor people in their normal living and working environments  Optimization of health care systems costs  Development of brand-new, mostly on-line diagnostics and therapeutic procedures.

Main tasks of pHealth for AAL I.Integration of sensors, signal conditioning RF receivers, for monitoring of both on-body and in the future also in-body bio- parameters (Body Area Network) II.Use of wireless networks for monitoring and localization III.Design of motion control system of the body and limbs of everybody IV.Design of intelligent real time Clinical Decision Support Systems The target is: To create integral solutions motivating and assisting elderly people to remain active and independent as long as possible.

Main components of Czech pHealth compliant with the above mentioned tasks Set of biosensors for all important vital signs –Task I Modern satellite navigation systems(GPS/EGNOS, GLONASS, GALILEO) –Task II Communication platform Bluetooth + GPRS –Task II RFID Long range platform – Task III Evaluation of bio-parameters by expert systemBioAnalyst – Task V Web “events initiated” GIS visualization – TaskIV – TBD with Mediinspect, Ltd., and HSRS,Ltd.

Czech pHealth projects 2012 I.Expert System for Disease Risk Warning II.System for monitoring of people with cardiovascular diseases and diabetes and/or handicapped people III.System for monitoring of risk pregnancy (not part of this presentation)

I. Expert System for Disease Warning “BioAnalyst” Program package BioAnalyst is a very efficient statistical software specifically designed and focused on differential diagnostics of various groups of diseases. It is based on multivariate analysis of biochemical and other clinical data.

Basic functions of the system  Simulating data via Monte Carlo modeling  Collecting of biochemical and other laboratory data  Optimizing number of necessary parameters for any group  Evaluating set of collected data for a real patient  Creating so-called “Disease Risk Warning Message”  Creating confirmed diagnostic clusters for any disease group

Goals of the system  Allows control of therapeutic process in time  Can significantly reduce laboratory costs  Effective tool for training of students and young physicians  Effective tool for “disease early stage screening”  Allows creating of a completely new set of diagnostic procedures

Example of disease groups  Cardiovascular diseases  Gilbert disease  Osteoporosis  Early stage diagnostics of some types of cancer  Frederickson disease  Diabetes mellitus

Example of heart risk evaluation

Example of Monte Carlo modeling

 Assistance for patients to improve their safety and independence  Monitoring of vital signs for chronic patients  Monitoring of home rehabilitation  Sending warning messages to patients  Recognition of severe falls of persons  Rapid assistance thanks to immediate awareness of those in charge Monitoring of people at home and outdoors

Developed PHS products  myXwb – RFID wrist band for indoor and outdoor localization of persons  myXcall – personal communication and localization unit and mobile server for myXwb units  BioAnalyst – expert system for on-line evaluation of disease risk  HeRo – HealthRobot – personal wrist band communication and localization unit with vital signs sensors – pO2, temperature, pulse, blood pressure - R&D stage

1.NXP ATOP module – GPS/GLONASS, GPRS, NFC 2.JENNIC RFID module – TOUMAZ ECG sensor 4.OrSense pO2, glucose sensors - planned 5.Bluetooth 4 module Commercial PHS products in use

myXcall personal unit

 Temperature  Pulse  Blood Pressure  pO2 HeRo

System for navigation of blind people

RFID personal unit

Partners  Immobiliser Central Europe, Ltd., Czech Republic  COMINFO, Inc., Czech Republic  Czech Technical University, Prague, Czech Republic  Charles University, Prague, Czech Republic  NXP Semiconductors, NL, The Netherlands  Mediinspect, Ltd., Czech Republic  BIOCONS, Ltd., Slovakia

Thank you! p