POD Compare and contrast asexual and sexual reproduction. What do you think triggers cells to divide? Give reasoning for your predictions
The structure of eukaryotic chromosomes
The Relationship between Chromosomes, DNA and Genes DNA – deoxyribose nucleic acid macromolecule, carries genetic information A gene is a short section of DNA http://www.hhmi.org/biointeractive/dna-packaging
DNA is tightly packed in the nucleus of every cell. DNA wraps around special proteins called histones which form loops of DNA called nucleosomes. These nucleosomes coil and stack together to form fibers called chromatin. Chromatin in turn forms larger loops and coils to form chromosomes.
TERMS YOU NEED TO KNOW:
Structure of a Chromosome
Chromosome Numbers Sex chromosomes - determine the sex of an organism Autosomes - All other chromosomes in an organism
Somatic Cells (body cells) – - 2 Sex chromosomes X or Y - all other chromosomes are autosomes Gametes (Sex cells) - half the number of chromosomes as a somatic cell - 1 sex chromosome
Example: Humans Somatic cells have 46 chromosomes Gametes 2 sex chromosomes women have two X chromosomes men have an X and a Y 44 autosomes Gametes 1 sex chromosome 22 autosomes
Chromosome Numbers Haploid and diploid are terms referring to the number of sets of chromosomes in a cell. diploid cells (2n) - Somatic cells (body cells), contains two complete sets of chromosomes every organism has a characteristic diploid number haploid cells (n) - Gametes (sex cells) have only one complete set of chromosomes the length and number of chromosomes is unique to each species of organism.
Chromosome Number 18 32 48 78 36 94 Organism Carrot Cat Chimpanzee Dog Earthworm Goldfish Lettuce http://www.ncbi.nlm.nih.gov/mapview/
Mactching sets of chromosomes in a diploid cell are called homologous chromosomes. Both chromo in a homologous pair contain information that code the same trait (genes). Example of trait: Eye color Are sex chromosomes homologous? Why or Why not?
Cell Division and Reproduction PBS : How Cells divide http://www.pbs.org/wgbh/nova/baby/divide.html#
Prokaryotic chromosomes Lack true nuclei DNA found in cytoplasm Most contain a single, circular DNA chromosome
The Prokaryotic Cell Cycle Cell Division in Prokaryotes/Asexual Reproduction BINARY FISSION is the division of a prokaryotic cell into 2 offspring cells. (asexual reproduction) The cell grows in size. DNA replication - The chromosome makes a copy of itself, resulting in two identical chromosomes Cytokinesis - The cell splits into two new cells. Each new cell contains identical genetic information as the original cell
A protozoan undergoes binary fission
Eukaryotic Cell Cycle The stages of life of a cell Interphase Mitosis Cytokinesis
Eukaryotic Cell Cycle http://highered.mheducation.com/sites/9834092339/student_view0/chapter10/control_of_the_cell_cycle.html
Cell Division in Eukaryotes A cell typically goes through stages during its life, growing and developing before it divides into new cells. The cell cycle is the repeating events that make up the life of a cell http://www.biologie.uni-hamburg.de/b-online/library/cat-removed/u4aos1p2.html#Chromosomes
Interphase Period of normal metabolic activity Carries on all usual functions Increases in size Synthesizes new proteins and organelles DNA Replication – DNA is duplicated (copied) Reminder: DNA exist as chromatin within the nucleus. Chromatin are thin uncoiled strands of DNA wrapped around a protein allows each new cell will have a complete copy of each chromosomes
The actual dividing of the cell consists of two steps: Mitosis cytokinesis
Mitosis The division of the Nucleus Process by which a nucleus divides into 2 identical nuclei Mitosis produces two daughter cells that are identical to the parent cell. If the parent cell is haploid (N), then the daughter cells will be haploid. If the parent cell is diploid, the daughter cells will also be diploid. N ® N 2N ® 2N This type of cell division allows multicellular organisms to grow and repair damaged tissue.
4 phases of Mitosis
Prophase the chromatin coils (condenses) to form visible chromosomes* nucleolus and the nuclear membrane begin to disappear centrosomes (centrioles) appear Spindle fibers start to form Centrioles begin to move to opposite ends
The constricted area of each chromatid is called a centromere The chromatin condensed into chromosomes each chromosome contains two identical halves called sister chromatids The constricted area of each chromatid is called a centromere Centromere Sister chromatids
Metaphase chromosomes are moved to the center of the cell (equator) by the spindle fibers attached to the centromeres The two sister chromatids of each chromosome are attached to spindle fibers from opposite ends of the cell
Anaphase The sister chromatids are separated from each other; now considered to be individual chromosomes The centromeres of each chromosome are pulled by the spindle fibers toward the opposite ends (poles) of the cell
Telophase after the chromosomes reach opposite ends of the cell, the spindle fibers breakdown the chromosomes return to less tightly coiled Chromatin new nuclear envelope begins to form around the chromosomes at each end of the cell End of mitosis Nuclear envlopes reappear
Cytokinesis The cell membrane begins to pinch the cell in two as cytokinesis begins the cytoplasm of a cell and its organelles are equally separated into two daughter cells Completes the process of cell division the new cells are now in interphase
Cytokinesis differs between plants and animals Plant cells have a rigid cell wall, so the plasma membrane does not pinch in. the material for the new cell wall is called the cell plate The cell plate and membranes gather and fuse along the equator, between two two nuclei forming two identical cells
Results: unicellular organisms remain as single cells in multicellular organisms, cell growth and reproduction result in groups of cells that work together as tissue to perform a specific function http://www.sumanasinc.com/webcontent/anisamples/majorsbiology/mitosis.html http://www.johnkyrk.com/mitosis.html http://www.biology.arizona.edu/Cell_bio/tutorials/cell_cycle/cells3.html http://biology.about.com/library/blmitosisanim.htm
Normal Control of the Cell Cycle Proteins regulate the progress of cell division Occasionally, cells lose control of the cell cycle. uncontrolled dividing of cells can result from proteins not functioning properly cancer is a malignant growth resulting from uncontrolled cell division