Peripheral neuropathy is the term for damage to nerves of the peripheral nervous system.nervesperipheral nervous system
classification Anatomical Etiological :causes Pathological symptomology
Anatomical Mononeuropathy mononeuropathy multiplex Generalized: polyneuropathy
etiological acquired VITAMIN D V:vascuilities, SLE,PAN,.. I:infection,HIV,CMV,EBV,leprosy T: truma A:autimmune M:Metabolic:DM,vit B12 defciency,hypothyrodism,renal hepatic,porphyria I:Infiltrative:sarcidosis, amylodosis N:Neoplasm: paraneoplastic D:Demyelinating,GBS(Guillian barre syndrome or Drugs Hereditary,
pathological Axonal demyelinating
onset Acute chronic
Signs and symptoms Motor :weakness+ lower motor neuron signs Sensory: +ve or –ve symptoms, gloves and stalk distribution Autonomic:incotenance, postural hypotention,
Work UP EMG and nerve coduction study Look for the causes LP: protien, glu,WBC (cytoalbumin dissociation)..GBS ANA,RF,vit B12,TFT,Glu leve,renal,… Nerve biopsy
GBS Acute inflamatory demyelinating poly radiculopathy Preceded by URTI, diarrhea Asending weaknesss It is emergency Diagnosed by EMG,NCS and LP(cyto albumin dissociation)