Asthma Medications ESAT 4001 Pharmacology in Athletic Training

Asthma Review of condition Use of inhalers and other medications –Epinephrine (EPIPEN) in acute attacks

Inhalers and Spacers MDI Spacer Nebulizer Problems with inhalers –Hand-breath coordination Nebulizer

Bronchiodilators (Beta-Adrenergic Agonists) Mostly used in inhaler form –Albuterol Proventil & ventolin Cause smooth-muscle relaxation ~ opening constricted airways Effects seen w/in 5-15 min; last 3-6 hr Intended for use for asthma

Bronchiodilators (Beta-Adrenergic Agonists) Side effects of inhalers –“Racing heart”, other cardiac irregularities, nervousness –Azmacort and flovent are steroid preparations ~ may be on banned lists

Anticholinergics Cholinergic receptor inhibitor –Leads to bronchodilation –Not as effective as beta adrenergic drugs

Systemic Corticosteroids Inhibit associated inflammatory response Used to treat symptoms associated with acute exacerbation Used in combination with  2 -agonist drugs 3-10 day course

Long Term Therapies Inhalation Corticosteroids Mast Cell Stabilizers Leukotriene Modifiers –Effective reduction of inflammation Long acting Beta Agonists –Bronchodilators –Onset is slower than short acting drugs Methylxanthines –Caffeine