TCVM Approach to Inflammatory Bowel Disease

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Presentation transcript:

TCVM Approach to Inflammatory Bowel Disease

IBD Group of GI disorders with inflammatory infiltrates in the lamina propria of SI & LI Damage from tissue cytokines Caused by Genetic factors Environment Feline IBD touch prep

IBD Ulcerative colitis Crohn’s disease (regional enteritis) Systemic disease (arthritis, uveitis, liver disease, etc.)

Crohn’s disease vs Ulcerative colitis

IBD- -Signs Dogs: Cats Other signs Chronic vomiting, diarrhea, weight loss Cats Vomiting followed by diarrhea Other signs Flatulence, gas, altered appetite, abdominal pain & mucois stools Dry hair coat Thickened loops of bowel on palpation

IBD- -Causes Infectious Dietary Genetic (Damp-Heat) (Stomach Heat/Stagnation) Genetic (Kidney Jing) Diagnosis usually by biopsy

IBD- -Treatment Anti-infectives Dietary Immunosuppressive Sulfasalazine (Azulfidine) Dietary Diet elimination Vitamin support (all but high vitamin C) Western herbals Bromelain/curcumin Ginger Cat’s Claw Immunosuppressive

Mechanism of Action of Azulfadine Antibacterial activity Local and systemic immunity-lymphs, IgG Arachidonic acid metabolism-PG, Thr, leukotrienes Free radical scavengers (5-ASA) Inhibit PAF, histamine release (mast cells)

TCM Pathology of IBD Excess Deficiency Parvovirus Heat Toxin/Damp Heat Qi/Blood Stagnation Deficiency SP Qi Deficiency Parvovirus

Heat Toxin/Damp Heat Signs Tongue Pulse Bloody/watery diarrhea (mucoid) with foul smell Acute Heat signs (nose/ears) Vomiting Thristy Tongue Deep red  yellow coating Pulse Superficial/Deep and fast

Qi-Blood Stagnation Signs Tongue Pulse Chronic diarrhea with stink smell Abdominal pain Vomiting Loss of appetite Tongue Purple or red Pulse Wiry

Spleen Qi Deficiency Signs Tongue Pulse Chronic diarrhea with undigested material Anorexia Loss of body weight (muscle mass) Exercise intolerance Tongue Pale Pulse Deep & weak

Parvovirus Signs Tongue Pulse Bloody diarrhea with mucous and/or foul odor Anorexia Vomiting Tongue Red & dry Pulse Fast (superficial or deep)

TCM Treatment of IBD Heat Toxin/Damp Heat Qi/Blood Stagnation Great Saussurea Coptis Qi/Blood Stagnation Xiang Lian San SP Qi Deficiency Shen Ling Bai Zhu Parvovirus Red Back Door

Great Saussurea Coptis Saussurea Mu Xiang Move Qi & relieve pain Coptis Huang Lian Clear Damp-Heat in the intestines Evodia Wu Zhu Yu Warm the middle Jiao & stop vomiting