Improving Prophylactic Treatment of GBS Positive Patients Michelle Blythers Literature Review Presentation Senior Project October 22, 2014.

Slides:

Advertisements

Similar presentations

Group B Streptococcal Disease in Neonates

Advertisements

TB/HIV Research Priorities: TB Preventive Therapy.

Journal Club October 2012 Supervised by Prof.Abdulrahim Rouzi Presented by Dr.Ayman Bukhari.

Tuberculosis in Children: Prevention Module 10C - March 2010.

Group B Streptococcus An overview of risk factors, screening, and treatment for moms and babies Erin Burnette, FNP February 2011 EBurnette.

Enhanced Perinatal Surveillance, Georgia

PRESENTATION ON SAFETY ISSUES RELEVANT TO HOME BIRTHS AND THE PROFESSIONALS WHO PROVIDE MATERNITY CARE SEPTEMBER 20, 2012 The Maryland Chapter of the American.

STREPTOCOCCUS GROUP A and B. Group B Streptococcus ● Group B Streptococcus is a bacterial infection of Streptococcus agalactiae. It is a facultative anaerobic.

Introduction to Evidence Based Medicine Pediatric Clerkship LSUHSC.

Department of Health and Human Services Measuring Clinical Lab Ordering Quality: Theory and Practice Steven M. Asch MD MPH VA, RAND, UCLA April 29, 2005.

Serum Procalcitonin Level and Other Biological Markers to Distinguish Between Bacterial and Aseptic Meningitis in Children A European Multicenter Case.

Journal Club Alcohol and Health: Current Evidence May-June 2006.

World Health Organization

Introduction to evidence based medicine

Drug and Therapeutics Committee Session 7A. Identifying Problems with Medicine Use: Indicator Studies.

Adherence to Sepsis Guidelines and Hospital Stay Elspeth Ferguson SCH Journal Club 6 th November 2012.

Cost-Conscious Care Presentation Follow-up Chest X-Ray in Patients Admitted for Community Acquired Pneumonia Huy Tran, PGY-2 12/12/2013.

Current international guidelines recommend 6–9 months of isoniazid (INH) preventive chemotherapy to prevent the development of active tuberculosis in.

Reconsidering risks of Early Onset Sepsis Dissecting the literature that informs the CDC Guidelines Elise C. Brown, MD, MPH CPMG Internal Medicine & Pediatrics.

Neonatal Group B Streptococcal Infections

Factors associated with perinatal deaths in women delivering in a health facility in Malawi Lily C. Kumbani, Johanne Sundby and Jon Øyvind Odland.

Perinatal CDC Prevention Guidelines Priscilla Joe, MD.

Evidence Based Medicine

Implementing a Rapid HIV Testing Guideline for L&D NNEPQIN April 30, 2007.

Study design P.Olliaro Nov04. Study designs: observational vs. experimental studies What happened?  Case-control study What’s happening?  Cross-sectional.

Welcome Enhanced Perinatal Surveillance (EPS) Meeting.

Periodontal Health and Birth Outcomes Secretary’s Advisory Committee on Infant Mortality – SACIM November 30, 2006 M. Ann Drum, DDS, MPH, Director Department.

Introduction To Evidence Based Nursing By Dr. Hanan Said Ali.

STRATEGIES FOR PREVENTION OF CVC INFECTIONS 1) Is chlorhexidine a more effective cutaneous antiseptic agent than povidone-iodine for CVC insertion and.

Evidence-Based Medicine Presentation [Insert your name here] [Insert your designation here] [Insert your institutional affiliation here] Department of.

Cohort Study. Objectives To discuss cohort study designs To discuss data from some cohort studies.

Community Acquired Pneumonia in the Emergency Department (ED) Emergency Department Nurses & Physicians Dr. Mark Cichon, Director; Bridget Gaughan, Manager.

RevMan for Registrars Paul Glue, Psychological Medicine What is EBM? What is EBM? Different approaches/tools Different approaches/tools Systematic reviews.

Respiratory CONNECT meeting Dr Julius Cairn. Risk stratification in PE Clinical parameters – shock, JVP, S3 Imaging – CTPA, echo Biomarkers – Troponin,

1 Exploring Alternative Antibiotic Treatment Regimens: Methodology and Implications Dr. Tabish Hazir MASCOT Study Group 2 nd ICIUM Conference 2004.

Changing Epidemiology of Bacteraemia in Infants aged 1 week to 3months Mekhala Ayya SCH Journal Club 3 rd April 2014 TL Greenhow, Yun-Yi Hung, Arnd M Herz.

A Practice-Based Intervention to Improve Time-to-Antibiotic Administration in Pneumonia Suspects at Mulago Hospital, Kampala, Uganda Luke Davis, MD Pulmonary.

I MPROVING PROPHYLACTIC TREATMENT OF GBS POSITIVE OBSTETRICAL PATIENTS Michelle Blythers Quality Improvement Project Professional Development Perspectives.

Evidence Based Medicine. What is Evidence Based Medicine? What qualifies as Evidence Based Medicine? Does Airrosti treat patients by utilizing an Evidence.

SCH Journal Club Use of time from fever onset improves the diagnostic accuracy of C-reactive protein in identifying bacterial infections Wednesday 13 th.

Afebrile Infants With UTI and the Risk for Bacteraemia Journal Club Sheffield Children’s Hospital Naheed Maher 7 th January 2015.

Sifting through the evidence Sarah Fradsham. Types of Evidence Primary Literature Observational studies Case Report Case Series Case Control Study Cohort.

Is the conscientious explicit and judicious use of current best evidence in making decision about the care of the individual patient (Dr. David Sackett)

1 EFFICACY OF SHORT COURSE AMOXICILLIN FOR NON-SEVERE PNEUMONIA IN CHILDREN (Hazir T*, Latif E*, Qazi S** AND MASCOT Study Group) *Children’s Hospital,

The Health Roundtable Postoperative IV Antibiotic Therapy for Children with Complicated Appendicitis: A Propensity Score-Matched Observational Study Presenter:

EVALUATING u After retrieving the literature, you have to evaluate or critically appraise the evidence for its validity and applicability to your patient.

Learning to Manage Health Information Measuring the Quality of Maternity Care Professor Suzanne Truttero Midwifery Advisor Department of Health 18 th March.

Research Design Evidence Based Medicine Concepts and Glossary.

Appropriate Testing for Children with Pharyngitis  Diagnosed with pharyngitis only…… and  Prescribed an antibiotic…… and  Received a group A streptococcus.

Evidence-Based Practice

Human Immune Deficiency Virus Infection Dr Huda Taha Sep 2015.

Jeanine Spielberger MD 9/23/2013 INTRAPARTUM ANTIBIOTIC PROPHYLAXIS FOR GROUP B STREPTOCOCCAL INFECTION.

Roundtable. Detection and treatment of TB Andrew Black.

Newborns At Risk for Sepsis Algorithm

Antibiotic Use on the Postnatal Ward Inching towards NICE Dr R Morris Dr M Pickup Dr S Banerjee Department of Neonatal Medicine, Singleton Hospital, Swansea.

Time for first antibiotic dose is not predictive for the early clinical failure of moderate–severe community-acquired pneumonia Eur J Clin Microbial Infect.

Dept. Paediatrics, Leicester Royal Infirmary, Leicester

GBS Prophylaxis indicated for mother? Adequate treatment?

Critical analysis of breastfeeding education in the hospital Abigail Sweet URI Undergraduate: College of Nursing Evaluation of Education Lactation Experts.

Fever in infants: Evaluation by

Table 1 Characteristics of the 968 Women in the Study Group

How to read a paper D. Singh-Ranger.

Evaluating Sepsis Guidelines and Patient Outcomes

Chronic Hepatitis C Virus Infection

Early Onset Sepsis: GBS

Inquiry into geographical inequalities in breast cancer

Evidence-Based Practice

BY ABDULJALEEL ELSHALWI MAHMOUD ELMABRI ANTIBIOTICS PROTOCOLS IN A NEONATAL INTENSIVE CARE UNITE OF AL-WAHDA HOSPITAL DERNA.

J. Bodilsen, C. T. Brandt, A. Sharew, M. Dalager-Pedersen, T

No matter what the type of genetic screening, certain core principles should be followed before a program is introduced. Principles of Screening • The.

Presentation transcript:

Improving Prophylactic Treatment of GBS Positive Patients Michelle Blythers Literature Review Presentation Senior Project October 22, 2014

Introduction A high priority should be placed on identifying Group B Streptococcus (GBS) positive mothers and the appropriate administration (>4 hours prior to delivery) of prophylactic antibiotics.

Importance of Change: GBS is the leading cause of sepsis, pneumonia and meningitis in the early newborn period, which is defined a the first week of life. Identifying/screening and adequately treating GBS positive mother’s, increases positive patient outcomes.

Article #1 Berardi, A.,Rossi,C.,Biasini, A. Minnitti, S., Venturelli, C., Ferrari, Faccinetti, F. (2011) Efficacy of intrapartum chemoprophylaxis less than 4 hours duration. The Journal of Maternal-Fetal and neonatal medicine 21(4):  The data in this article were collected over 12 months, in 2 different hospitals.  This was a quantitative study to compare rate of vertical transmission of GBS in women with no other risk factors.  The findings were valid.

Article #2 Turrentine, M. Greisinger, A., Brown, K., Wehmanen, O., Mouzoon, M. (2013). Duration of intrapartum antibiotics for group b streptococcus on the diagnosis of clinical neonatal sepsis. Infectious Disease in obstretrics and Gynocology, 1-6.doi: /2013/  This particular study was done in a large facility which delivers over 8,000 infants a year.  It was retrospective cohort study of.  The results were that infants whose mothers received <4 hours intrapartum antibiotic therapy, were more often diagnosed with clinical sepsis.

Article #3 Silva, J., Stein, A., Schunemann, H., Bordin, R. Kuchenbecker, R., Drachler, M. (2013), Academic detaling and adherence to guidelines for group b streptococci prenatal screening: a randomized controlled study. BMC Pregnancy & Childbirth 2013, 13: /13/68.  This was a random controlled study consisting of physicians  It is imperative that health care workers stay abreast of the latest guidelines so that they can properly teach the patients.  The results proved that academic detailing increased the prevalence of GBS screening in that particular population.

Summary: The research studies presented all provide sufficient evidence that supports the CDC recommended guidelines.  Article #1 is a level IV. Evidence from a well-designed case-control and cohort study.  Article #2 is a level IV. Evidence from a well-designed case-control and cohort study.  Article #3 is a level II. Evidence obtained from a well- designed Randomized Controlled Trial.