Bremer (1935) - encephale & cerveau isolê prep.

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Presentation transcript:

Bremer (1935) - encephale & cerveau isolê prep. RETICULAR FORMATION - History Cajal (1909) - reticulum Bremer (1935) - encephale & cerveau isolê prep. Magoun (1949) - EEG = behav. “arousal”; Ascending Reticular Activating System (ARAS). Lindsley (1950) - sensory cuts Moruzzi (1958) - NRPO; EEG desynchronization Fuster (1958) - “attention” Lindsley (1959) - humans

RETICULAR FORMATION Medulla Pons Midbrain Bremer (1935) Cerveau Isolé Encephale Isolé Sensory input cuts (Lindsley, 1950) Trigeminal Nerve (V) Midpontine - Pretrigeminal Preperation NRPO = n. reticularis pontis oralis (Moruzzi, 1958)

Fuster (1958): Rhesus - WGTA

EEG waves of waking & sleep stages Spindles + K-complex » reduced sensory input to brain REM = ß + Ø (Paradoxical sleep: n. reticularis magnocellularis, gigantocellular tegmental field)

The cycle of sleep stages through a night Awake Stage 1 & REM Slow-wave sleep

Changes in sleep over the course of life 90 yrs.