EU-US Innovation Seminar John Fraser AUTM, Immediate Past-President Executive Director, Commercialization Florida State University

Global Pharmaceutical Regulation 2007: Tackling Regional Priorities Florida State University College of Law Tallahassee, Florida April 5-7, 2007 Prof Fred Abbott: Attendees: Individuals from – WHO, WIPO, MSF; PAHO; Washington DC, Argentina, India, etc

What is AUTM? The professional association that brings together 3500 technology transfer professionals in more than 30 countries to define, develop and promote leadership excellence in academic technology transfer –66% are employed in academic technology transfer offices. 33% are in corporations, service businesses or government. –80% reside in the US, 9% in Canada and 11% in other countries. –2050 attendees at AGM in San Fran from 36 countries

What do we do ? We impact the economy by partnering with the private sector to develop products that save lives, improve the quality of life and increase productivity and competitiveness.

The Mission Universities have a social contract with society. In return for public funding, universities will educate the next generation, create knowledge about the world and its problems and perform community service (clinical studies, economic development). Academic technology transfer is a relatively new activity within the social contract.

The Mission To enhance the reputation of our institution by helping them achieve their goals of education research and community service by facilitating research partnerships with the private sector to the long term benefit of all. Build the research base ! The strategy is to assist development of products with an outcome of saving lives, improving the quality of life and enhancing productivity and global competitiveness.

I will talk about: What we do. and How well we do it. Outcomes, Impact, not inputs and outputs.

Purpose of Bayh-Dole Act Created to specify with certainty, the ownership of inventions from federally funded research in universities and small businesses. Created to provide incentives and responsibility for commercialization. Created as a Job Creation Act and an Economic Development Act. Insisted on manufacturing in the USA.

Sequential model of development and funding

Outputs: Growing volume of US academic technology transfer $41 billion in US R&D expenditures (FY’05); 4,932 new licenses; 28,349 current active licenses; 527 new products introduced in the market; 3,641 new product introductions in last 8 years 628 new spinout companies; 5,171 new spinouts since 1980.

New Metrics Recognition that technology transfer is part of the core mission of the academic institution. Its impact is beyond the traditional AUTM metrics. Its external impact is to society – outcomes - in lives saved, patients with improved quality of life and increasing industrial productivity

New, New, New AUTM practitioners are reaching out to academic scholars to research our field; In the Public Interest: Nine Points to Consider in Licensing University Technology (Chronicle of Higher Education – Mar 7/07); New Metrics: (outside TTO, internal Univ; outside Univ, community based); Embracing our role in local economic development; Preliminary results of publicly funded research inventing a molecule now a FDA approved drug.

Where is the Action ? Fiscal Year 2004, billions University expenditures for research: $ 42.3 From federal sources: $ 28.3 (67%) From Industry: $ 3.0 (7%) University Licensing Income: $ 1.4 billion FY % licensing deals in life sciences – 64%. % income from life sciences 80%

Where is the Action ? FYTotal Licenses Options Start- Ups Small Co’s Large Co’s ‘993,79212%50%38% ‘044,62414%54%32%

U’s FY2005 %FTEs%3yr cum Royalties %Median Age Top 2014%23435%2,357 B $$77%1983 Top 3021%32248%2,597 B $$85%1983 All %667100%3,064 B $$100%1989 Gardeners in the Garden with Tools over Time

AUTM Data FY ,000 disclosures (discoveries) $200B + Research Opportunity Assessment (Triage) 50,000 Patent Applications 25,000 Licenses 50% <$10k cum. 125 > $1M/year 2,500 Start - ups $2M : 1 disclosure Commercial potential Technical advantages Protectability Inventor profile 50% do not move forward 25% (10% lics / 2.5% discl.) Positive exit (liquidation) License Income (0.5%) From Disclosure to Patent Royalties

The Annual Survey tells: What we do. The Better World Report tells: How well we do it.

AUTM’s Better World Project Telling the story of the outcomes of technology transfer in human terms An e-database of stories from Canada, the US, the UK. Two publication (and e-versions) with stories highlighting social and economic impact Of the 125 stories, 20% were products developed by university licensed start-up companies. Anecdotal evidence to supplement our Licensing data.

Why is AUTM doing this? To communicate the value of academic technology transfer

Tactical Mobile Power Technology: 10-kilowatt Vehicular Power Source (VPS-10K) Mississippi State Univ. Chirp Sonar to Locate Underwater Buried Objects Florida Atlantic Univ. TPMT: Diagnostic Test to Tailor Drug Dosage to Genetic Profile St. Jude Children's Research Hospital Optigrate Inc. Method of Developing Holograms Univ. of Central Florida Underwater In-Situ Mass Spectrometer Univ. of South Florida Restasis Univ. of Georgia AU MEDS Auburn Univ. FoodSource Lures Auburn Univ. Helping Emphysema Victims Breathe Again Univ. of Florida Falconview Georgia Inst. of Technology Sponsored Programs Database Western Kentucky Univ. Partners for a Healthy Baby: Home Visiting Curriculum Florida State University TN KY MS ALGA FL

Diverse Markets Agriculture28 Biotechnology23 Chemical 9 Computer 8 Construction 5 Educational18 Electronics23 Environment 9 Food 7 Health Services12 Information Services 6 Machinery 3 Medical 102 Miscellaneous29 Pharmaceuticals57 Software18 TOTAL 357

The Real Issues – Culture Companies value secrecy. Universities value dissemination of information; Companies value the bottom line. Universities value peer appreciation; Companies define the direction of research. Faculty follow the research results. Companies value attribution via patents. Faculty value attribution by publications

More information:

Macro Success Factors Innovation Climate (Start-Ups) - treatment of entrepreneurs - financial environment - risk tolerance - liquidity of investments - demographics of country/city Innovation Climate (Existing Companies) - NIH, globalization