Why do some allergens effect different people in different ways?

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Presentation transcript:

Why do some allergens effect different people in different ways? Deanna Dailey Dr. Chan’s Human Phys G Block

What is an allergic reaction? An allergic response is when an antibody binds to and antigen and irritation occurs. Types of reactions: Rash or hives Swelling: epically of the lips, tongue, throat, face Dizziness Nausea/ diarrhea Anaphylaxis http://www.walgreens.com/marketing/library/contents.jsp?doctype=2&docid=8700 https://mnfoodallergies.wordpress.com/tag/food-allergy-reactions/

Steps to an allergic reaction The antigen enters the body Triggered B-cells to produce IgE antibodies These antibodies target the specific allergen This releases histamine to battle the allergen causing a reaction. Depending on how sensitized, the genes of the person, or how much histamine is released, the person can have a mild or major reaction. http://www.etetens.com/biobili/biocourse/allergies.html

Why are there different effects? Genes MHC Controlled by different genes and they have many different variations. Socioeconomic background Immunity towards allergens was a defense mechanism Variation in total and specific IgE: effects of ethnicity and socioeconomic status Exposure The more you are exposed, the worse the symptoms can be.

Works Cited