Synthetic Biology Presentation by Brown iGEM Team.

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Presentation transcript:

Synthetic Biology Presentation by Brown iGEM Team

Building Biotechnology

Bacterial Photography

E. Coli that smell!

Biofuel s GreenFuel Company

Invade Cancer Cells 1. Aerobic Conditions 2. Low Oxygen Detected! 3. INVASION!

How do we build these?

Parts Devices Systems

DNA: AATGAATATCCAGATCG

Biological Part: Promoter

Biological parts are building blocks made of genetic material

--- Different Parts connect together Promoter --- Gene Terminato r This is a device

MIT Parts Registry A database with standardized genes for easy assembly and reusability.

MIT Parts Registry From about 100 parts in 2004 to about 2000 parts in 2007 But still a lot of work to be done!

Characterization How does this part work? What does it do?

Recap A set of tools and parts to engineer biology

What is iGEM? Internationally Genetically Engineered Machines Competition Brown’s Team: 7 undergraduate students

Our Projects

Lead Sensor Lead contamination is health problem Expensive to sense lead We need cheap solution that doesn’t take long

Lead Sensor

Tri-Stable Switch

Turn on/off three different proteins in cell Differentiation of stem cells Tissue Engineering

Synthetic Biology at Brown University Synthetic Biological Systems Professor Wessel Biomechanics Professor Richardson Biomaterials Professor Webster

Our Sponsors