Introduction to The Cmed Group

About Cmed 2 Cmed Group Cmed Group is an innovative clinical trials services and advanced software provider that includes two divisions: Cmed Clinical Services, a full-service clinical research organization, and Cmed Technology, an eClinical technology provider. Central to our business is Timaeus, a unified on-demand platform that supports Study Design through Reporting. Cmed Clinical Services Cmed Clinical Services is a long-established, flexible CRO with offices in the UK, US and Romania offering project management, clinical monitoring, data management, biostatistics, medical affairs, regulatory, consulting, and medical writing services. While Cmed’s area of specialization is the design and delivery of both innovative and traditional phase I to IIb clinical trials, Cmed increasingly uses its experience and capabilities for existing clients phase III programs and for functional service provision of biometrics. Cmed Technology Profile Cmed Technology, an eClinical technology provider, offers Timaeus: a single platform for electronic trial design, paper and electronic data capture, monitoring, coding, data management and reporting. The Timaeus eClinical platform is designed to respond on-demand to the needs of investigators, data managers and study teams. Timaeus’ unique architecture uses advanced distributed cloud computing and mobile technologies to provide the freedom to manage any type of data, for any protocol, anywhere. Timaeus has been used in every phase of clinical research – including early phase, pivotal and late phase studies as well as in globally established and emerging markets –covering single-unit clinics to multi-thousand person studies operating across Europe, Asia, Africa and the Americas.

Key Corporate Facts 3  The Cmed Group employs 350+ people  Four offices worldwide, two in the USA, one in the UK and one in Romania  Staff turnover has consistently been below industry average  Greater than 90% repeat business rate working with over 30 customers world-wide  Successful organic year-on-year growth since its birth in 2000  The Cmed Group currently works with both biotechnology organisations and major pharmaceutical companies  Preferred provider for four of the top ten pharmaceutical companies and a number of biotechnology firms

4 Cmed’s Mission  Cmed is the largest CRO dedicated to the design and delivery of innovative and traditional early phase I to IIb clinical trials  Delivered over 450 early phase trials in the last ten years  Award winning innovative clinical projects  Complex trial designs, such as adaptive  In-house drug development consulting team – build the right study  Begin with the end in mind, focus on the commercial objective  Thorough analysis and application of retrospective data  Robust full service operations to seamlessly deliver from planning through to reporting – do the study right

Corporate Structure 5

Broad Global Reach 6 Austria Belgium Denmark France Germany Israel Italy Netherlands Poland Russia Romania Spain Sweden Switzerland United Kingdom Kenya South Africa Canada Latin America United States Australia Hong Kong India Korea Singapore