MBV2010/BIO2140 Colloquium, February 5
RULES Multiple choice Only one correct answer seconds to answer No textbook, computer, mobile phone, please There will be a prize for the group with the most correct answers.
Example 4789 x 9548 = ?? A B C D
Example 4789 x 9548 = ?? 0
Nucleic acids were first isolated in the … A 17 th century B 18 th century C 19 th century D 20 th century 1
Nucleic acids were first isolated in the … 1 Friedrich Miescher
The major form of DNA in cells is … A A-DNA B B-DNA C C-DNA D Z-DNA 2
The major form of DNA in cells is … 2
A A-DNA B B-DNA C C-DNA D Z-DNA 3 Which form of DNA is shown here ?
3
Most RNA in cells is … A messenger RNA B transfer RNA C micro RNA D ribosomal RNA 4
Most RNA in cells is … 4
Transcriptomes consist of … A messenger RNA B transfer RNA C ribosomal RNA D all of the above 5
Transcriptomes consist of … 5
The genetic code A consists of 62 codons B has 3 stop codons C is used in transcription D specifies 25 amino acids 6
The genetic code 6
Restriction endonucleases A are located in the nucleus of cells B are sequence-specific C were discovered in the 1980s D are present in bacteria and fungi 7
Restriction endonucleases 7
Which compound is not found in nucleic acids? A Pyridines B Purines C Phosphate D Ribose 8
Which compound is not found in nucleic acids? 8 PyridinePyrimidine
The secondary structure of proteins is stabilized by … A Ionic bonds B Hydrogen bonds C Disulfide bonds D Hydrophobic interactions 9
The secondary structure of proteins is stabilized by … 9
DNA polymerases A synthesize DNA in 3’ -> 5’ direction B require a primer to initiate DNA synthesis C require ATP D bind only to DNA 10
DNA polymerases 10
The human nuclear genome … A is split into 24 chromosomes B Is the largest genome known to date C Contains about 2 billion bp D Contains about 40,000 genes 11
The human nuclear genome … 11 Human female karyogram
Reverse transcriptases A Synthesize RNA B Use DNA as template C Are viral enzymes D Are present in all eukaryotic cells 12
Reverse transcriptases 12
ORF scanning A is used to find intron sequences B is used to find functional genes C is used to identify protein-coding genes D is used to find intergenic sequences 13
ORF scanning 13
A codon bias … A is present in intergenic regions of a genome B is used to find protein- coding genes C is only present in eukaryotic genomes D has been found for all codons 14
A codon bias … 14
Expression of genes can be analyzed by A northern analysis B Southern analysis C Comparative genomics D PCR 15
Expression of genes can be analyzed by 15
An alpha-helix A is a DNA structure B is a protein structure C winds to the left D is stabilized by base stacking 16
An alpha-helix 16
ß-sheets are stabilized by A hydrophobic bonds B ionic bonds C hydrogen bonds D all of the above 17
ß-sheets are stabilized by 17