Insulin Produced by beta-cells in pancreas Hormone involved in regulation of blood glucose levels tells liver, muscle and fat cells to take up glucose.

Slides:

Advertisements

Similar presentations

Biochemistry to Cells Chapters 2 and 3.

Advertisements

Transcription and Translation Flip Book Your Name Your Class Period.

TRANSLATION The process of converting the information stored in mRNA into a protein is called translation mRNA carries information from a gene to a structure.

Chapter 11 DNA and Genes. Proteins Form structures and control chemical reactions in cells. Polymers of amino acids. Coded for by specific sequences of.

DNA StructureDNA Structure  DNA is composed of a chain of nucleotides.

Transcription Transcription is the synthesis of mRNA from a section of DNA. Transcription of a gene starts from a region of DNA known as the promoter.

Cellular Metabolism Chapter 4. Introduction Metabolism is many chemical reactionss Metabolism breaks down nutrients and releases energy= catabolism Metabolism.

Transcription and Translation

Protein Synthesis From DNA to Proteins!. What is a gene? A small segment of DNA that provides instructions for making proteins.

Protein Synthesis 12-3.

What is the job of p53? What does a cell need to build p53? Or any other protein?

SC.912.L.16.5 Protein Synthesis: Transcription and Translation.

RNA and Protein Synthesis

- The Wonderful Hormone - INSULIN By Jeremy Wynn Cell Physiology.

 During DNA replication, the two strands of the original parent DNA molecule, shown in blue, each serve as a template for making a new strand, shown in.

Protein Synthesis The process of putting together amino acids to form proteins in the cell. The process of putting together amino acids to form proteins.

RNA (ribonucleic acid) – single stranded nucleotide chain – ribose sugar – G-C and A-U – Uracil instead of Thymine – Different types: – mRNA, tRNA, rRNA.

RNA and Protein Synthesis. How does DNA determine our traits?

How does DNA control cell activities?. Protein Production The sequence of nucleotides in DNA contains instructions for producing proteins. The sequence.

HORMONES OF PANCREASE. INSULIN This is a polypeptide hormone synthesized from the β-cell of I slets Langerhans of the pancreas. It is synthesized as a.

Protein Synthesis: Transcription & Translation.

LG 4 DNA and Protein Synthesis Ribonucleic Acid RNA – Steps in Protein Synthesis Transcription – Translation – Functions of Proteins Structural – Signals.

Do Now: On the “Modeling DNA” handout, determine the complimentary DNA sequence and the mRNA sequence by using the sequence given.

Gene Expression Gene: contains the recipe for a protein 1. is a specific region of DNA on a chromosome 2. codes for a specific mRNA.

DNA, RNA, PROTEIN REVIEW. 1. What are all living things made of? 2. In what organelle is the genetic material located? 3. What is the name of the molecule.

You have been given a mission:  You must crack the code that you have been given. How many letters does it look like it requires to make just one English.

Protein Synthesis. Review…  DNA:  Found in the nucleus  Double stranded  Contains the instructions for controlling the cell (including instructions.

Nucleic Acids Nucleic acids provide the directions for building proteins. Two main types…  DNA – deoxyribonucleic acid  Genetic material (genes) that.

DNA What is the Function of DNA?. Nucleic Acids : Vocab Translation page 183Translation Transcription Protein Synthesis RNA DNA Complementary Introns.

DAY 2. Warm Up What type of RNA copies DNA? – mRNA What is this process called? – Transcription.

C Morritt Protein Synthesis Starfish Text pages 472 to 481.

Molecules to Eye Color DNA, RNA and Protein Synthesis.

Regulation of BloodGlucose. Blood filled with glucose (after eating) When blood glucose levels are high, the Pancreas secretes insulin which is a chemical.

Molecules to Eye Color DNA, RNA and Protein Synthesis.

12-3 RNA and Protein Synthesis Page 300. A. Introduction 1. Chromosomes are a threadlike structure of nucleic acids and protein found in the nucleus of.

Transcription & Translation. Objectives: Relate the concept of the gene to the sequences of nucleotides in DNA Sequence the steps involved in protein.

Chapter  Relate the concept of the gene to the sequence of nucleotides in DNA  Sequence the steps involved in protein synthesis ◦ DNA  mRNA =

©2015 Science Island 1 1 What does DNA stand for?

SC.912.L.16.3 DNA Replication. – During DNA replication, a double-stranded DNA molecule divides into two single strands. New nucleotides bond to each.

GROUP 2 DNA TO PROTEIN. 9.1 RICIN AND YOUR RIBOSOMES.

Rajshahi University.

DO NOW EOC REVIEW PG 199 NAME THE 3 PARTS OF THIS STRUCTURE:

ORGANIC COMPOUNDS.

Gene Expression Gene: contains the recipe for a protein

The making of proteins for …..

RNA & Protein Synthesis

CH 11: DNA, RNA, AND PROTEIN SYNTHESIS

Written Response #4 What are the six essential elements?

How DNA and RNA make Proteins.

Transcription -The main purpose of transcription is to create RNA from DNA because RNA leaves the nucleus to carry out its functions but DNA does not -A.

Glucose C6H12O6. Glucose C6H12O6 Fuel for the Cells.

REPLICATION, TRANSCRIPTION & TRANSLATION REVIEW Power point

Protein Synthesis Step 2: Translation

DNA RNA Protein Synthesis Review

DNA and the Genome Key Area 3a Gene Expression RNA.

Protein Synthesis.

Protein Synthesis DNA to Proteins.

Protein Synthesis.

Protein synthesis.

Nucleic Acid Molecules -DNA, RNA and ATP -Structure and Functions

DNA Replication vs. Protein Synthesis

Macro-molecules “The Stuff of Life”.

Key Area 1.3 – Gene Expression

Unit 4 - The Natural Environment and Species Survival

The Production of Proteins by DNA

Presentation transcript:

Insulin Produced by beta-cells in pancreas Hormone involved in regulation of blood glucose levels tells liver, muscle and fat cells to take up glucose from the blood and store it as glycogen (liver cells, muscle cells) or fat (fat cells) Liver cells Muscle cells Fat cells Class Project

Insulin Gene is located on chromosome 11 at locus 11p15.5 Gene ID: 3630 Gene Symbol: INS Class Project

B chain (30 AA) A chain (21 AA) Insulin A single gene is responsible for preproinsulin Undergoes extensive protein modifications following translation to remove the D chain and C chain regions The remaining A chain and B chain regions form insulin Preproinsulin = 106 AA Insulin = 51 AA C chain (30 AA) D chain (30 AA) Class Project

Insulin Can be found in protein data bank at: Can also be viewed at: Active form = monomer composed of A chain and B chain The A chain is composed of 21 amino acids The B chain is composed of 30 amino acids The A and B chains are held together by two disulfide bonds Inactive form (stored form) = hexamer held together by zinc ions disulfide bonds Class Project

Model Transcription 1.Use the RNA nucleotides to construct an mRNA copy of the preproinsulin gene (be sure to use the correct strand – the one given in the research paper) Model Translation 2.Translate the preproinsulin mRNA into a protein by using the nucleotide sequence to place the amino acids in the correct order (write the abbreviation for each amino acid on the little slip of paper) Model Protein Editing 3.Perform the edits shown in the slides Form two disulfide bonds Remove the D chain and then the C chain In Class Activity: Protein Synthesis