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Presentation transcript:

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. Frank Jaksch, Founder & CSO Muirlands Blvd. Suite G Irvine, CA USA NPA Marketplace June 13 th, 2012 Green Chemistry: Better for You, Better for the Planet

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 2 Green Chemistry – US EPA Definitions Green chemistry, also known as sustainable chemistry, is the design of chemical products and processes that reduce or eliminate the use or generation of hazardous substances. Green chemistry applies across the life cycle of a chemical product, including its design, manufacture, and use. Green chemistry is a highly effective approach to pollution prevention because it applies innovative scientific solutions to real-world environmental situations.

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 3 Sustainable Chemistry Hierarchy Products and processes should be designed to the highest level of this hierarchy and be cost- competitive in the market. Design products to be less hazardous to human health and the environment Use feedstocks and reagents that are less hazardous to human health and the environment Design syntheses and other processes to be less energy and materials intensive Use feedstocks derived from renewable resources or from abundant waste Reuse or Recycle Chemicals Treat Chemicals to Render Them Less Hazardous

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 4 Non-Natural-Natural Ingredients Vitamin C – Most ingredient supply is synthetic Other vitamins – synthesis and fermentation Amino Acids – most are produced by fermentation or synthesis Caffeine - synthesis Carotenoids - synthesis Resveratrol – synthesis Co-enzyme Q10 - fermentation

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 5 Misconceptions about “Natural” Just because an ingredient is natural does not mean that it is more green or sustainable than a synthetic version of the same ingredient Ingredients that are manufactured starting with botanicals, fruits, vegetables, etc…are processed using solvents and chemicals In many cases synthetic or fermentation processes are more clean, green and sustainable compared to extraction from natural material. Some extraction processes generate incredible amounts of solvent or chemical waste

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 6 Some Other Issues with Natural Just because there is supply today does not mean that there will be sustainable supply with increased demand Wildcrafting – illegal wildcrafting for high value botanicals Use of endangered plants – sometimes not a problem when demand is low, but not sustainable if demand increases.

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 7 Natural Identical Synthesis Some natural compounds can be made synthetically so that the are identical to the natural compound Nature identical compounds are so close that they are chemically indistinguishable from a compound isolated from the plant. Natural identical compounds tend to be more cost effective, clean green and natural Vitamin C is the best example

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 8 Vitamin C Example Most vitamin C included in products is synthetic Biomass for natural extraction is abundant, however it not an efficient way to manufacturer commercial quantities of the ingredient Natural Vitamin C is 5 to 10X more expensive than synthetic Nature identical Vitamin C Acerola extract standardized to Vitamin C is a good example

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 9 Summary The most sustainable and green production methods do not always start with nature Nature identical ingredients are often needed to provide sustainable and economic solutions Synthetic does not equal bad There are many examples of natural identical ingredients in the market THE BOTTOM LINE: You need to do an appropriate amount of due diligence on the ingredients used in your products

This document contains confidential information, and neither this document nor the information contained herein may be disclosed, summarized, reproduced, disseminated or quoted or otherwise referenced in any manner, in whole or in part, without the express prior written consent of ChromaDex Corporation. 10 Questions? Frank Jaksch, Founder and CEO ChromaDex, Inc Muirlands Blvd. Suite G Irvine, CA USA