+ Other Traits and Pedigrees Genetics

+ Complex Characteristics and Sex Influenced Traits Complex Characteristics Characteristics that are due to more than one gene. Eye color, hair color, skin color, height, etc. Most characteristics where there is a wide range of possibilities. Sex Influenced Traits Not the same as sex link traits Influenced traits are carried on autosomes They are influenced due to the hormones that each gender produces Male Pattern Baldness – A trait where males start going. This trait is actually a dominant trait and only one allele is needed to have it, in men. However, it is sex influenced. Women actually need 2 dominant alleles in order to express this trait.

+ Helpful Reminders Complete Dominance Can be done as an autosomal trait (A and a as alleles) or sex linked (X R, X r and Y). Only two phenotypes exist and one can cover up the other. If it is autosomal both men and woman can be hybrid, carriers, or heterozygotes Codominance Two different letters for the alleles (R and B), both capital, look for spots, stripes, or speckles Incomplete Dominance Same letter for the alleles (R and r), look for a blend (red + white = pink); 3 phenotypes Dihybrid FOIL! Sex Linked Use the sex chromosomes (X R, X r and Y) Woman can be carriers; Men cannot be carriers, they either have it or they don’t Blood Multiple alleles (I A, I B, and i o ); 4 phenotypes

+ Pedigrees A way to follow a family lineage Convenient for looking at traits as they pass on from parent to offspring, especially in the case of a lethal or debilitating disorder

+ Pedigrees A circle represents a female. A shaded in circle represents a female that has a specific trait. A square represents a male. A shaded in square represents a male that has a specific trait. A horizontal line indicates two individuals that have produced offspring A vertical line coming down indicates the offspring that they have produced. Siblings are connected by a horizontal line that drops down into vertical lines. Offspring go in birth order.

+ SteveAmy Sally JenniferJosh Allen Christina Ben How many females are in this pedigree? How many males are in this pedigree? How many children do Steve and Amy have? Who is the 2 nd born child of Steve and Amy? How is Sally related to Amy? Allen Sally is her granddaughter

+ Tay-Sachs Disease is an autosomal recessive disorder. It is caused by the absence of the enzyme Hex-A. This causes cells to become damaged. This will result in progressive neurological disorders eventually leading to death. SteveAmy JenniferJosh Allen Christina Ben Sally Six months are Ben and Christina had Sally, they discovered that Sally had Tay-Sachs disease. Since it is an autosomal recessive disorder: What does this mean about Ben and Christina? If they conceive another child, what would be the chance that they would also have Tay-Sachs? They are carriers. 25%