FOSBE 2009 3 rd Conference on Foundations of Systems Biology in Engineering Denver, Colorado Inverness Hotel & Conference Center August 9-12, 2009 www.fosbe.org.

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FOSBE rd Conference on Foundations of Systems Biology in Engineering Denver, Colorado Inverness Hotel & Conference Center August 9-12,

Organization Conference chair Conference chair Mike Henson, Department of Chemical Engineering, UMass Mike Henson, Department of Chemical Engineering, UMass Conference co-chairs Conference co-chairs David de Graaf, Vice-President of Biotherapeutics and Integrative Biology, Boehringer-Ingelheim David de Graaf, Vice-President of Biotherapeutics and Integrative Biology, Boehringer-Ingelheim Hiroaki Kitano, Director of Sony Computer Science Laboratories, Japan Hiroaki Kitano, Director of Sony Computer Science Laboratories, Japan Linda Petzold, Department of Computer Science, UCSB Linda Petzold, Department of Computer Science, UCSB Hans Westerhoff, Professor of Systems Biology, The University of Manchester, United Kingdom Hans Westerhoff, Professor of Systems Biology, The University of Manchester, United Kingdom Facilitators Facilitators Kathryn Jurgensen & Robin Craven Kathryn Jurgensen & Robin Craven International Program Committee in place International Program Committee in place

Technical Program & Sponsors SundayMondayTuesdayWednesday Morning Training Workshop Drug Development Network Modeling Circadian Systems Afternoon Training Workshop Free time Free time & Task Force Meeting Free time EveningReception Alternative Fuels Education Synthetic Biology NightKeynote Poster Session I Poster Session II Award Ceremony & Banquet

Confirmed Speakers Erin O’Shea, Harvard (Keynote) Erin O’Shea, Harvard (Keynote) Adam Arkin, UC-Berkeley Adam Arkin, UC-Berkeley David Balaban, Amgen David Balaban, Amgen Bill Bentley, U. Maryland Bill Bentley, U. Maryland Frank Doyle, UC-Santa Barbara Frank Doyle, UC-Santa Barbara Dan Gillespie, Gillespie Consulting Dan Gillespie, Gillespie Consulting Albert Goldbeter, U. Brussels, Belgium Albert Goldbeter, U. Brussels, Belgium Bruce Gomes, Pfizer Bruce Gomes, Pfizer Vassily Hatzimanikatis, EPFL, Switzerland Vassily Hatzimanikatis, EPFL, Switzerland Erik Herzog, Washington U. Erik Herzog, Washington U. Ravi Iyengar, Mount Sinai Medical School Iya Khalil, Gene Network Sciences Art Lander, UC-Irvine Doug Lauffenburger, MIT Jim Liao, UC-Los Angeles Jens Nielsen, Chalmers U. Technology, Sweden Erik Schadt, Merck Deanne Taylor, Brandeis U. Masaru Tomita, Keio U., Japan Hiroki Ueda, Kyushu U., Japan Eberhard Voit, Georgia Tech Huimin Zhao, U. Illinois

Student Training Workshop Sunday, August 9, 8:30 am - 5:00 pm Network Robustness (Frank Doyle, UCSB ) Network Robustness (Frank Doyle, UCSB ) Applications of Systems Biology (Bruce Gomes, Pfizer ) Applications of Systems Biology (Bruce Gomes, Pfizer ) Bioenergetics and Biochemical Network Thermodynamics (Vassily Hatzimanikatis, EPFL) Bioenergetics and Biochemical Network Thermodynamics (Vassily Hatzimanikatis, EPFL) Circadian Entrainment and Rhythm Generation (Erik Herzog, Washington U and Hiroki Ueda, Kyushu U) Circadian Entrainment and Rhythm Generation (Erik Herzog, Washington U and Hiroki Ueda, Kyushu U) Macromolecular Biophysics as the Underpinning of Molecular Systems Biology (Deanne Taylor, Brandeis U) Macromolecular Biophysics as the Underpinning of Molecular Systems Biology (Deanne Taylor, Brandeis U) Computational Methods for Discrete Stochastic and Multiscale Simulation (Linda Petzold, UCSB) Computational Methods for Discrete Stochastic and Multiscale Simulation (Linda Petzold, UCSB) Parameter Estimation and Structure Identification in Metabolic Networks (Eberhard Voit, Georgia Tech) Parameter Estimation and Structure Identification in Metabolic Networks (Eberhard Voit, Georgia Tech)

FOSBE Founders Award Established to recognize exceptional contributions to the systems biology field Established to recognize exceptional contributions to the systems biology field Award winner was selected by a committee comprised of the five conference co-chairs of FOSBE 2009 and the two chairs of the previous FOSBE meetings Award winner was selected by a committee comprised of the five conference co-chairs of FOSBE 2009 and the two chairs of the previous FOSBE meetings Prof. Doug Lauffenburger (MIT) was selected as the first award winner Prof. Doug Lauffenburger (MIT) was selected as the first award winner Prof. Lauffenburger will be honored at the banquet the final night of FOSBE 2009 Prof. Lauffenburger will be honored at the banquet the final night of FOSBE 2009

Inverness Hotel

Budget Received Received Army Research Office - $10K Army Research Office - $10K Amgen - $5K Amgen - $5K AstraZeneca - $5K AstraZeneca - $5K Entelos - $5K Entelos - $5K Promised Promised NSF - $15K NSF - $15K Merck - $5K Merck - $5K ICB - ~$4K ICB - ~$4K Total - $49K Total - $49K Needed - $66K Needed - $66K

Deadlines December 1, 2008: Abstracts for contributed papers December 1, 2008: Abstracts for contributed papers January 15, 2009: Notification of acceptance January 15, 2009: Notification of acceptance March 15, 2009: Submission of contributed papers March 15, 2009: Submission of contributed papers May 1, 2009: Review of papers returned May 1, 2009: Review of papers returned June 1, 2009: Submission of final papers June 1, 2009: Submission of final papers June 9, 2009: Early registration deadline June 9, 2009: Early registration deadline August 9, 2009: Conference August 9, 2009: Conference