Exam Review: Question 1 Which of the following factors is not a teratogen? Environmental chemicals Drugs taken by the mother during pregnancy Multifactorial inheritance Maternal factors
Exam Review: Question 1 Answer Which of the following factors is not a teratogen? Environmental chemicals Drugs taken by the mother during pregnancy Multifactorial inheritance Maternal factors
Exam Review: Question 2 Which of the following statements about human birth defects is true? During the organogenetic period, teratogenic agents disrupt development and cause major developmental abnormalities Major anomalies are more common in newborn infants than in early embryos Cigarette smoking during pregnancy do not have any effect on the developing embryo Adrenal hyperplasia, resulting in androgen production in females do not cause masculinization of the external genitalia
Exam Review: Question 2 Answer Which of the following statements about human birth defects is true? During the organogenetic period, teratogenic agents disrupt development and cause major developmental abnormalities Major anomalies are more common in newborn infants than in early embryos Cigarette smoking during pregnancy do not have any effect on the developing embryo Adrenal hyperplasia, resulting in androgen production in females do not cause masculinization of the external genitalia
Exam Review: Question 3 True False During the first two weeks of development, teratogenic agents usually kill the embryo or have no effect. True False
Exam Review: Question 3 Answer During the first two weeks of development, teratogenic agents usually kill the embryo or have no effect. True False
Exam Review: Question 4 True False Congenital rubella syndrome (CRS), characterized by cataracts, heart defects and deafness, is caused by an infective agent that infects the mother and crosses the placenta to cause maldevelopment in the fetus. True False
Exam Review: Question 4 Answer Congenital rubella syndrome (CRS), characterized by cataracts, heart defects and deafness, is caused by an infective agent that infects the mother and crosses the placenta to cause maldevelopment in the fetus. True False
Exam Review: Question 5 Which of the terms listed below best describes the following situation: chromosome 15 and 18 exchange genetic information? Deletion Mosaic Translocation Inversion
Exam Review: Question 5 Answer Which of the terms listed below best describes the following situation: chromosome 15 and 18 exchange genetic information? Deletion Mosaic Translocation Inversion
Exam Review: Question 6 An infant is born with cataracts, cardiac defects and deafness. During the intrauterine period, the infant was most likely infected with: Treponema pallidum Toxoplasma gondii Varicella-zoster virus Cytomegalovirus Rubella virus
Exam Review: Question 6 Answer An infant is born with cataracts, cardiac defects and deafness. During the intrauterine period, the infant was most likely infected with: Treponema pallidum Toxoplasma gondii Varicella-zoster virus Cytomegalovirus Rubella virus
Exam Review: Question 7 An individual with pentasomy of the sex chromosomes would possess a total chromosome number of: 47 48 49 50
Exam Review: Question 7 Answer An individual with pentasomy of the sex chromosomes would possess a total chromosome number of: 47 48 49 50 *44 autosomes X, X, X, X, X
Exam Review: Question 8 Down syndrome is a result of meiotic non-disjunction of chromosome: 13 18 21 X
Exam Review: Question 8 Answer Down syndrome is a result of meiotic non-disjunction of chromosome: 13 18 21 X
Trisomy 21
Exam Review: Question 9 Congenital anomalies associated with trisomy 21 can be classified as a: Disruption Non-disjunction Deformation Dysplasia
Exam Review: Question 9 Answer Congenital anomalies associated with trisomy 21 can be classified as a: Disruption Non-disjunction Deformation Dysplasia
Nondisjunction
Exam Review: Question 10 Which of the following is the most common cause of human congenital anomalies? Multifactorial inheritance Chromosomal abnormalities Mutant genes Environmental agents Unknown etiology
Exam Review: Question 10 Answer Which of the following is the most common cause of human congenital anomalies? Multifactorial inheritance Chromosomal abnormalities Mutant genes Environmental agents Unknown etiology
Causes of Human Congenital Anomalies or Birth Defects
Exam Review: Question 11 In dizygotic twins, zygotes that implant separately and apart would be expected to have: Separate placentae and amniotic cavities A shared placenta and a common amniotic cavity A shared placenta and separate amniotic cavities Separate placentae but a common amniotic cavity A shared umbilical cord
Exam Review: Question 11 Answer In dizygotic twins, zygotes that implant separately and apart would be expected to have: Separate placentae and amniotic cavities A shared placenta and a common amniotic cavity A shared placenta and separate amniotic cavities Separate placentae but a common amniotic cavity A shared umbilical cord
Exam Review: Question 11 Parturition is the earliest stage of placental development. True False
Exam Review: Question 11 Review Parturition is the earliest stage of placental development. True False *“Parturition (childbirth) is the process during which the fetus, placenta, and fetal membranes are expelled from the mother's reproductive tract.” Moore and Persuad. The Developing Human.
Exam Review: Question 12 Perinatology is the branch of medicine concerned with the well-being of both the fetus and newborn infant. True False
Exam Review: Question 12 Answer Perinatology is the branch of medicine concerned with the well-being of both the fetus and newborn infant. True False
Exam Review: Question 13 Intrauterine growth restriction can result from: Maternal vascular disease Intrauterine infection Cigarette smoking Alcohol consumption All of the above
Exam Review: Question 13 Above Intrauterine growth restriction can result from: Maternal vascular disease Intrauterine infection Cigarette smoking Alcohol consumption All of the above
Exam Review: Question 14 Which can be performed earlier in a pregnancy? CVS Amniocentesis
Exam Review: Question 14 Answer Which can be performed earlier in a pregnancy? CVS Amniocentesis
Exam Review: Question 15 During the organogenetic period of the development, teratogens have very little affect on the embryo. True False
Exam Review: Question 15 Answer During the organogenetic period of the development, teratogens have very little affect on the embryo. True False
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