Supplemental data Fig. S1 Figure S1 Circulation bilirubin levels in CRC patients and non-tumor patients. Circulation bilirubin levels in CRC patients were.

Slides:

Advertisements

Similar presentations

G-Fectin TM 1. A novel transfection reagent developed by Genolution 2.Cationic lipid based 3. no cell splitting is required 4. Whole transfection can be.

Advertisements

Suppl. Figure 1 A B Suppl. Figure 1. Relative (A) miR-21 and (B) miR-224 expression levels in HCC tumors in different stages (I,II,III,IV) assessed by.

Figure S1. RNA-seq results for caveolin-1 (Cav1). Upper panel: UCSC genome browser view. Lower panel: quantification o f Cav1 expression based on RNA-seq.

Supplemental Figure cells/ well DLD-1 ALDH+/CD133+ DLD-1 ALDH- /CD133- Supplemental Figure 2.

Table S1. Hypoxia increases signaling through JNK in colon cancer cell lines in a cell-specific manner Shown are the ratios of c-Jun phosphorylation during.

Supplemental Figures Byrne et al. Metabolic vulnerabilities in endometrial cancer.

Marker (%) Normal EPCs Mean ± SM (%) MMD EPCs Mean ± SM (%) CD ± ± 6.8 KDR27.3 ± ± 8.90 CD ± ± 3.93 CD ±

10 h5 h 0 h Supplemental Figure 1 14 h 16 h 24 h Untreated Supplemental Figure 1 Untreated cells were analyzed using live cell imaging microscopy. Time.

Supplementary Figure 1A-B A H1299 RH LC3-I / II P-GSK-3 (Ser21/9) GSK-3α/β β-actin β-catenine P-GSK-3 (Tyr279/216) B.

Supplementary Figure 1 Supplementary Figure 1. Screen for small-molecule compounds modulating luciferase activity. Claudin-4 reporter cells were seeded.

Supplementary Figure 1. The effect of 17-DMAG on the growth of lung cancer cells with Met amplification Tumor cells were continuously treated with increasing.

Fig. S1 Fig. S1. Experimental design of DSS-induced colitis (A) and AOM/DSS-induced colon carcinogenesis (B).

SIRTs inhibitor: Sirtinol Supplementary Figure S3A Supplementary Figure S3 Sirtinol but not EX527 or PDF-170 significantly enhances ithe cytotoxic and.

Normal skin tissue Supplementary Fig 1A KLF4 has a tumor suppressive function in human skin cancer. Skin cancer tissues were deparaffinized and IHC was.

SNU423 SK-Hep1 HepG2 HA22T AR GAPDH Supplemental Fig. S1 Endogenous AR expression in various HCC cell lines Supplemental Fig. S2 Multiple E:T ratio for.

Products > U87 Transfection Reagent (Glioblastoma Cells) Altogen Biosystems offers the U87 Transfection Reagent among a host of 100+ cell line specific.

1A 1B 1C 1D Supplementary Fig. 1. Treatment of VEGF-C with the human acute myeloid leukemic cell line,THP-1, induced angiogenesis in vitro. (A and B) Treatment.

Products > PC-3 Transfection Reagent (Prostate Cancer Cells) Altogen Biosystems offers the PC-3 Transfection Reagent among a host of 100+ cell line specific.

Altogen Biosystems offers the 786-O Transfection Reagent among a host of 100+ cell line specific In Vitro Transfection Kits. 786-O Transfection Reagent.

Supplemental Materials: Anti-apoptotic BCL-2 family proteins as 5-Azacytidine sensitizing targets and determinants of response in myeloid malignancies.

Supplementary Figure 1 A C E B D F ** untreated Anti-miR-375 * * Mtpn

B A P-AXL P-AXL AXL AXL P-MET P-MET MET MET P-Akt-473 P-Akt-473 AKT

Astragaloside IV Enhances Cisplatin Chemosensitivity in Non-Small Cell Lung Cancer Cells Through Inhibition of B7-H3 Cell Physiol Biochem 2016;40:

Ke Xu, Ph.D. Putuo Hospital and Cancer Institute,

A. B. BxPC-3 PANC h h h h h 100 *** * 72 h Cell viability (%) 80 *** *** Cell viability (%) 80 *** *** 60 *** ***

Cytochrome-P450 2B1 gene silencing attenuates puromycin aminonucleoside-induced cytotoxicity in glomerular epithelial cells Niu Tian, Istvan Arany, David.

A B C FIGURE S1 D E F G H.

Heme oxygenase-1 mediates the anti-inflammatory effect of molecular hydrogen in LPS- stimulated RAW macrophages Hong-Guang Chen, Ke-Liang Xie, Huan-Zhi.

Volume 76, Issue 8, Pages (October 2009)

Phosphoinositide 3-kinase inhibitors protect mouse kidney cells from cyclosporine- induced cell death E. Sarró, O. Tornavaca, M. Plana, A. Meseguer, E.

Volume 120, Issue 5, Pages (April 2001)

Histone Deacetylase Inhibitors Sensitize Human Non-small Cell Lung Cancer Cells to Ionizing Radiation Through Acetyl p53-Mediated c-myc Down-Regulation

Inhibition of cytochrome P450 2E1 and activation of transcription factor Nrf2 are renoprotective in myoglobinuric acute kidney injury Zhe Wang, Sudhir.

Marissa V. Powers, Paul A. Clarke, Paul Workman Cancer Cell

FL cells are dependent on BCL6 in a NOTCH2-dependent manner.

Interferon-γ Protects from Staphylococcal Alpha Toxin-Induced Keratinocyte Death through Apolipoprotein L1 Anne M. Brauweiler, Elena Goleva, Donald Y.M.

(A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza) for 4 d. (A) ZR75-1 cells were treated with 1 μM 5-aza-2′-deoxycytidine (5-Aza)

A B 20% O2 5% O2 C 5% O2 + NAC DAPI gH2AX pLKO.1 GFP-SOD1 S 0.1Gy

a b MCF-7 TR2 MCF-7 TR2 (Fold change) MTT Assay , (Fold change)

Volume 19, Issue 8, Pages (August 2017)

Marissa V. Powers, Paul A. Clarke, Paul Workman Cancer Cell

Volume 125, Issue 2, Pages (August 2003)

Volume 30, Issue 6, Pages (June 2008)

DNAPKcs is required for DNA repair in the presence of androgen.

Supplementary Figure 2. Effect of IL-32 and siRNA of IL-32 on melanoma, colon and prostate cancer cell growth and apoptosis as well as IL-32 expression.

Pioglitazone inhibits aromatase expression in human preadipocytes.

Supplemental Figure 1A – I

Integrin α5β1 Activates the NLRP3 Inflammasome by Direct Interaction with a Bacterial Surface Protein Hye-Kyoung Jun, Sung-Hoon Lee, Hae-Ri Lee, Bong-Kyu.

Volume 107, Issue 7, Pages (October 2014)

A CYP7A1 CYP7A AICAR (2 mM) * 0.8 mRNA expression

Nehad Abdulgader Shaer Pathophysiology

Cytochrome-P450 2B1 gene silencing attenuates puromycin aminonucleoside-induced cytotoxicity in glomerular epithelial cells Niu Tian, Istvan Arany, David.

Supplementary Fig. S1 BCL2 5’flanking ctrl siRNA luc

Effects of XIST on glioma cell proliferation and chemoresistance to TMZ Effects of XIST on glioma cell proliferation and chemoresistance to TMZ (A) siRNA-NC/siRNA-XIST.

Collagen Synthesis Is Suppressed in Dermal Fibroblasts by the Human Antimicrobial Peptide LL-37 Hyun Jeong Park, Dae Ho Cho, Hee Jung Kim, Jun Young.

The Membrane-Lytic Peptides K8L9 and Melittin Enter Cancer Cells via Receptor Endocytosis following Subcytotoxic Exposure Masayuki Kohno, Tomohisa Horibe,

Epithelial to Mesenchymal Transition in an Epidermal Growth Factor Receptor-Mutant Lung Cancer Cell Line with Acquired Resistance to Erlotinib Kenichi.

Loss of Class III β-Tubulin Induced by Histone Deacetylation Is Associated with Chemosensitivity to Paclitaxel in Malignant Melanoma Cells Kiyomi Akasaka,

Volume 18, Issue 3, Pages (March 2010)

A B C D E control CORM-2 (10mM) iCORM (10mM) L-NAME (500mM)

JAK inhibitors suppress IL-17–induced expression of IκB-ζ.

Silencing hOGG1 triggers caspase-3 and caspase-7 activation in response to H2O2 in GM00637 cells. Silencing hOGG1 triggers caspase-3 and caspase-7 activation.

The role of p53 in H2O2-mediated cell death of hOGG1-deficient H1299 lung carcinoma p53 null cells. The role of p53 in H2O2-mediated cell death of hOGG1-deficient.

Bcl-2 and caspase inhibition fails to inhibit BAMLET-induced cytotoxicity in MCF-7 cells. Bcl-2 and caspase inhibition fails to inhibit BAMLET-induced.

TFAP2A knockdown inhibits cell growth by targeting HIF-1α signaling.

Effect of GSK3β inhibition on cell survival and proliferation of glioblastoma cells. Effect of GSK3β inhibition on cell survival and proliferation of glioblastoma.

Synergistic cytotoxicity of 17AAG and TNF treatment in human lung cancer cell lines. Synergistic cytotoxicity of 17AAG and TNF treatment in human lung.

Fig. 3. KMS99220 inhibits activation of NFκB signaling via HO-1 induction. (A) BV2 cells were treated with 10 µM KMS99220 for 1 h, and then treated with.

A B Supplement Fig. 1. MMP-2 inhibition does not induce autophagy and suppress α-MSH -induced melanogenesis (A) Melan-a cells transiently transfected with.

Curcumin decreases viability and proliferation of Bcr-Abl-expressing cells. Curcumin decreases viability and proliferation of Bcr-Abl-expressing cells.

Presentation transcript:

Supplemental data Fig. S1 Figure S1 Circulation bilirubin levels in CRC patients and non-tumor patients. Circulation bilirubin levels in CRC patients were analyzed by an ABL800 FLEX blood gas analyzer, and the values were compared between CRC and non-tumor. Values are means ± SE. See text for details.

a b Figure S2 Cytotoxicity of ZnPP (a) and hemin (b) on C26 cells. C26 cells were treated with different concentrations of ZnPP or hemin; percent of dead cells after treatment was determined by MTT assay. Values are means ± SD. Supplemental data Fig. S2

Figure S3 Effect of carbon monoxide (a) and heme oxygenase-1 (HO-1) siRNA (b) on chemosensitivity of C26 colon cancer cells to THP. C26 cells were pretreated with HO-1 siRNA (30 nM) for 24h, or carbon monoxide releasing molecule (CORM2, 10 μM) for 1h, and treated by THP for 48h. Cell viability after treatment was determined by MTT assay, and the data was described as the percent viability of cells under different treatments. Vehicle indicates the result for cells treated with TransMessenger Transfection Reagent only (without siRNA); siRNA indicates the result for cells transfected with siRNA for HO-1 mRNA. Inset of (b) shows the results of RT-PCR of HO-1 in C26 cells treated by HO-1 siRNA. Values are means ± SD. * P < 0.05, ** P < See text for details. Supplemental data Fig. S3 Vehicle siRNA b * ** a * *

Figure S4 Cytotoxicity assay of THP with/without hemin or ZnPP using LDH cytotoxicity assay kit in C26 cells. C26 cells were treated with different concentrations of THP in the presence/absence of hemin (1 μM) or HO inhibitor ZnPP (0.5 μM); percent of dead cells after treatment was determined by LDH cytotoxicity assay. Values are means ± SD. Supplemental data Fig. S4