AVIAN INFLUENZA: PREVENTION OF RESURGENCE IN OYO STATE Nigerian Veterinary Medical Association Oyo State Conference 28 August, 2013 Dr. Omolade A. Oladele (DVM., MVSc., P.hD., MCVSN) Avian Diseases Unit, Dept. of Veterinary Medicine, University of Ibadan, Ibadan.

Outline Poultry industry in Nigeria & relevance. Avian influenza: History, Nigerian situation. Disease Why Nigeria is at risk. Prevention of resurgence Role of Public sector. Role of private sector Thailand example Rural poultry A challenge to all stakeholders. 210/8/2015NVMA Oyo State: Oladele, O.A

Introduction Poultry production sector is impt in the agricultural & economic devt, food security. The Nigerian poultry industry has an estimated million birds (FAO, 2008) comprising chickens, turkeys, ducks & quails. 25% commercially farmed, 15% semi-com., 60% backyard (rural). Hen eggs: 526,400 tonnes Chicken meat: 221,750 tonnes % of Nigerians are engaged in poultry production. 310/8/2015NVMA Oyo State: Oladele, O.A

Nigerians consume 62g/hd/day protein Only 7.9g of this is animal protein. (2008 Country profile: Food Security Indicators –FAO, 2010) WHO’s recommendation: 46g/day – women 56g/day –men ( based on complete protein found in animal sources). This deficiency can easily be addressed by increasing poultry meat and egg production. However, disease is a major constraint to the growth of the industry & a major concern for the health of consumers. 410/8/2015NVMA Oyo State: Oladele, O.A

AVIAN INFLUENZA? An infectious viral disease of birds characterized mainly by respiratory signs, depression, reduced feed and water intake, diarrhoea, decrease in egg production and quality + nervous signs. 510/8/2015NVMA Oyo State: Oladele, O.A

History: First identified in Italy more than 100 years ago and was called ‘Fowl Plague’. First Influenza pandemic occurred in Another pandemic occurred in ‘Hong Kong flu’ in caused by H3N2. Outbreak of H5N1 in Hong Kong in * Poultry population was destroyed within 3 days. * Believed to have prevented a pandemic. Outbreak of H9N2 in Hong Kong in /8/2015NVMA Oyo State: Oladele, O.A

History: Last Pandemic Outbreak of H5N1 in Hong Kong in February Outbreak of H7N7 in Netherlands in Outbreaks of H5N1 in Vietnam and Thailand in Outbreak of H5N1 in Turkey in Outbreak of H5N1 in Nigeria – Kaduna State in January, Outbreak of H5N1 in Nigeria – Lagos State in March, /8/2015NVMA Oyo State: Oladele, O.A

Nigeria:  First outbreak in Jan., 2006 –Kaduna state.  No. of suspicious cases – 1675  Positive cases – 300  Last outbreak – 24 th July, Kano & Katsina states.  Positive cases detected in 25 States + FCT.  Over 1 million birds depopulated with compensations paid. 810/8/2015NVMA Oyo State: Oladele, O.A

Classification of Influenza Viruses Influenza viruses are classified into A, B and C. Group A – Avian group; may also affect pigs and humans. Group B – Humans only. Group C – Mammals only, especially humans and pigs. New serotypes emerge every year. 910/8/2015NVMA Oyo State: Oladele, O.A

Avian Influenza virus: Type A influenza virus. Family – Orthomyxoviridae. Subtypes – surface proteins (HA; NA) H and 9 N subtypes. Broadly classified into LPAI and HPAI. Survives for long periods at moderate temperature and indefinitely in frozen materials. 1010/8/2015NVMA Oyo State: Oladele, O.A

Host Species:  All birds are susceptible. - domestic poultry particularly. - migratory water fowls are natural reservoirs of AI virus.  Humans, horses, pigs and some wildlife species may be infected with influenza viruses.  A cycle of infection exists btw birds & swine. 1110/8/2015NVMA Oyo State: Oladele, O.A

1210/8/2015NVMA Oyo State: Oladele, O.A

Transmission: 13 Migratory water fowls International movt. of poultry, poultry equipment & people. Introduction of AI into any country. ContactManureEquipmentVehiclesEgg cratesHumans 10/8/2015NVMA Oyo State: Oladele, O.A

14 Migratory water fowls 10/8/2015NVMA Oyo State: Oladele, O.A

Why should we be concerned? It’s effect on the Poultry industry. * animal protein supply * increased poverty level Public health importance. 1510/8/2015NVMA Oyo State: Oladele, O.A

Why Nigeria is at Risk? Extensive & largely unpatrolled borders. Nigeria is in the fly-paths of wild birds from Asia & middle east. Extensive uncontrolled movt. of humans & livestock rapid spread in the event of outbreak. High proportion of smallholder poultry farms with minimal level of biosecurity. Lack of standards in poultry production and marketing. integrated farming and marketing through poorly regulated LBM are high risk enterprises. 1610/8/2015NVMA Oyo State: Oladele, O.A

Prevention of Resurgence of HPAI Disease surveillance Improved biosecurity practices Humane depopulation & proper disposal of infected & exposed birds Vaccination These measures require public and private sector participation. Public policy (Govt.) instruments to induce optimal private sector participation. 1710/8/2015NVMA Oyo State: Oladele, O.A

The Role of Public Sector Provision of information & technical assistance. Incentives for disease outbreak surveillance & improved biosecurity practice. Penalty for non-compliance. Farm subsidies tied to following best mgt practice (biosecurity). Compensation for depopulation of culled birds, appropriate disposal & lost mkt value. Incentives for vaccination. 1810/8/2015NVMA Oyo State: Oladele, O.A

Information & Technical Assistance Farmers require sufficient information on: -HPAI ( some may accept significant poultry losses as ‘normal’) -Prevention strategies to reduce likelihood of infection. -Prompt containment of outbreak. Technical assistance with regards to: -Disinfection -Vaccination -Etc. 1910/8/2015NVMA Oyo State: Oladele, O.A

Surveillance Monitoring system should be in place for early disease detection. Prompt disease reporting. Proper incentives in place for prompt dse reporting. Lack of compensation, an impediment to dse reporting e.g. Cambodia (Rushton et al., 2004) & endemicity of HPAI. To be conducted by govt. Vet. Service Agency. Usually a major project involving private sector participation. Testing laboratory is the core element. 2010/8/2015NVMA Oyo State: Oladele, O.A

Traceability A system that enables tracing of movt. of poultry and poultry products should be instituted to identify dse origin in the event of outbreak. 2110/8/2015NVMA Oyo State: Oladele, O.A

Improved Biosecurity Practices Essentially the role of the private sector (producers). Most HPAI outbreak occurred in smallholder production systems with minimal biosecurity. Prevent exposure of poultry to wild birds. No access to feed and water. Prevent introduction of infected new poultry into existing flocks. Limit access into poultry houses. Thoroughly clean & disinfect clothing, shoes & equipment before & after use. Etc. 2210/8/2015NVMA Oyo State: Oladele, O.A

The Thailand Situation According to the Department of Livestock Development (DLD), Ministry of Agriculture and Cooperatives of Thailand in 2006 (Kanarat, 2007)  147 breeder farms – 16,030,512  7,456 broiler farms - 169,271,750  2,188 layer farms - 49,217,273 To ensure food safety, Livestock farm standards were issued. Compliance is voluntary but compulsory for farmers who wants to send their birds to slaughter houses approved for export. 2310/8/2015NVMA Oyo State: Oladele, O.A

 Broiler Farm Standard (2002)  Chicken Breeder Farm Standard (2003)  Poultry Hatchery Standard (2003)  Layer Farm Standard (2003)  Duck Breeder and Duck Farm Standard (2003)  Regulation on Traceability of Livestock Products (2003)  Notification of the DLD on the Control Measures on the Detection of Prohibited Substance in Feed and Veterinary Drug or Chemical Residues in Poultry (2003) 2410/8/2015NVMA Oyo State: Oladele, O.A

In 2003, DLD issued three Standard Operating Procedures (SOPs), as follows:  Requirements for obtaining standard farm accreditation for farmers.  Inspection of broiler standard farm by DLD farm inspectors.  Supervision over broiler standard farm for DLD- registered farm veterinarians. 2510/8/2015NVMA Oyo State: Oladele, O.A

The key ingredients in these regulations, notifications and SOPs are: Good agricultural practice Good veterinary practice Good hygienic practice Biosecurity Penalty in case of non-compliance 2610/8/2015NVMA Oyo State: Oladele, O.A

Feed, drinking water and pharmaceuticals used in DLD-registered farms must comply with set standards. 2710/8/2015NVMA Oyo State: Oladele, O.A

Action Steps by Thai Govt. 1)Initiation of Standard Farm System. 2)Poultry farms were encouraged to apply for accreditation. 3)Farmers were trained on farm standardisation and good agricultural practice – Govt. agencies & private sector to upgrade farms and farm operations. 4)Applications were assessed, farms were inspected & evaluated by DLD team. 5)Accredited farms remain under annual surveillance for renewal. 2810/8/2015NVMA Oyo State: Oladele, O.A

6)Regulatory officers and Veterinarians are continually trained by DLD. 7)Veterinarians of accredited farms must attend DLD training courses and get registered by DLD after passing performance evaluation. 2910/8/2015NVMA Oyo State: Oladele, O.A

Rural Poultry: Constraint to effective control of AI in Nigeria. An important segment of our rural socio-economy. Comprises of domestic poultry species reared extensively and usually as a mix. Scavengers with no restriction of movement. Vet. care is almost non-existent. Application of biosecurity measure is almost impossible. Effective means of spread of diseases. Could serve as continual source of virus; an endemic situation. 3010/8/2015NVMA Oyo State: Oladele, O.A

3110/8/2015NVMA Oyo State: Oladele, O.A

3210/8/2015NVMA Oyo State: Oladele, O.A

Prevention of Resurgence: A Challenge to All Research Institutions – research on epidemiology, vaccines and virus. Surveillance. Government – policy making (stds. in production & marketing) Poultry Vet. – provides expert advice to government and implements govt. policies. Customs Dept. – trade regulation. Prevent smuggling. Extension workers – educate farmers. Food safety agency – ensure consumption of wholesome poultry and poultry products. Poultry farmers – cooperation on the implementation of policies. Consumers - ensure consumption of wholesome poultry. 3310/8/2015NVMA Oyo State: Oladele, O.A

Comparmentalization and zoning in diseases control rec by OIE 3410/8/2015NVMA Oyo State: Oladele, O.A

References: Kanarat, S. (2007). Animal production food safety in Asia:Development of on-farm food safety in Thailand’s poultry industry. 25 th Conference of the OIE Regional Commission for Asia, the Far East and Oceania. UNDPs, July 2006, Socio- Economic Impact of Avian Influenza in Nigeria, UNDP Nigeria, Abuja. World Bank, Project performance assessment report. Federal republic of Nigeria. Avian influenza control and Human Pandemic Preparedness and Response Project (IDA 41600). 3510/8/2015NVMA Oyo State: Oladele, O.A

3610/8/2015NVMA Oyo State: Oladele, O.A

3710/8/2015NVMA Oyo State: Oladele, O.A

3810/8/2015NVMA Oyo State: Oladele, O.A

3910/8/2015NVMA Oyo State: Oladele, O.A

4010/8/2015NVMA Oyo State: Oladele, O.A

4110/8/2015NVMA Oyo State: Oladele, O.A

4210/8/2015NVMA Oyo State: Oladele, O.A

4310/8/2015NVMA Oyo State: Oladele, O.A

44 The Veterinarian as a Guide for the Poultry industry 10/8/2015NVMA Oyo State: Oladele, O.A

4510/8/2015NVMA Oyo State: Oladele, O.A