Call from Anonymous Foundation Remove financial barriers to most effective long-term reversible methods –Promote LARC use Provide no-cost contraception.

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Presentation transcript:

Call from Anonymous Foundation Remove financial barriers to most effective long-term reversible methods –Promote LARC use Provide no-cost contraception & make a population impact: –Teen pregnancy –Repeat abortion procedures

MYTHS Regarding IUCs Survey of St. Louis Women (N=1,665) 50% of women surveyed believe IUC is SAFE –Common safety concerns: Pelvic Pain36% Infertility30% Cancer14% STDs 11% 61% underestimate the effectiveness Hladky, et al. Obstet Gynecol 2011

Contraceptive Cohort Study Recruit 10,000 participants over 4 years –Remove cost barriers to long-term methods Copper IUD (ParaGard) LNG IUD (Mirena) Implant (Implanon) –Participant choice 2-3 years follow-up Assess continuation, satisfaction –Population outcomes

Long-Acting Reversible Contraception LNG-IUS 99% effective 20 mcg levonorgestrel/day Up to 5 years Copper T IUD 99% effective Copper ions Up to 10 years Subdermal Implant 99% effective 60 mcg etonogestrel/day Up to 3 years

CHOICE: Recruitment Sites

CHOICE: Inclusion Criteria years Primary residency in STL City or Country Sexually active with male partner (or soon to be) Does not desire pregnancy during next 12 months –Desires reversible contraception Willing to try a new contraceptive method

Study Recruitment Location9,256 2 Abortion clinics17% 8 Community clinics14% University-based research clinic Word-of-mouth Provider referrals 69%

Contraceptive CHOICE Project: Study Details 10 ELIGIBLE Tiered Contraceptive Counseling LNG-IUS Cu-IUD Implant DMPA Pills Patch Ring Other 94% 87% 81% Secura G, Am J Obstet & Gynecol 2010 Madden T, Contraception 2012

Baseline Characteristics 11 Age (years)N% Racen% Black White Other ,033

Baseline Characteristics (N=9,256) 12 SESn% Public assistance Trouble meeting basic needs Insurancen% None Private Public

Baseline Characteristics 13 ParityN% Unintended pregnancy History of STI

LARC Acceptance % LNG-IUS46.0 CuT380A11.9 Implant16.9 DMPA6.9 Pills9.4 Ring7.0 Patch1.8 Other< %

Choice of LARC Methods in Adolescents

Evaluation of CHOICE Outcomes –Short term: Effectiveness Continuation & satisfaction –Long-term Population-based outcomes –Unplanned pregnancies: »Repeat abortions »Teen births

NEJM CHOICE Publication

Unintended Pregnancy Rates in CHOICE Cohort August 2007 through July 2011 –615 reported pregnancies –459 (75%) unintended –334 contraceptive failures

Unintended Pregnancy by Contraceptive Method Winner, et al. NEJM HR adj = 22.3 (95% CI 14.0, 35.4) TWENTY-FOLD DIFFERENCE!

Method Failure by Age Winner NEJM 2012 HR adj = 1.9; 95% CI 1.2, 2.8

12- & 24-Month Continuation: Overall Cohort Method12-Month (%)24-Month (%) LNG-IUS Copper IUD Implant Any LARC DMPA OCPs Ring Patch Non-LARC Peipert, et al. Obstet Gynecol 2011; O’Neil, et al. Obstet Gynecol In Press

Contraceptive CHOICE Project Population Outcomes

Abortion Data: RHS

P-value KC:STL Repeat Abortion

Percentage of Abortions that are Repeat Abortions P-value KC:STL <0.001

Pregnancy Outcomes: CHOICE Compared to U.S. CHOICE Data: Unpublished; U.S. Data: Finer 2011, Jones 2011 CHOICE Annual RateU.S. RateReduction Pregnancy * 63% Unintended pregnancy * 43% Abortion ^ 47% All rates per 1,000 women years * 2006 data ^ 2008 data

NEJM CHOICE Publication

Teen Outcomes: CHOICE Compared to U.S. CHOICE Data: Unpublished; U.S. Data: Kost 2012 CHOICE Annual Rate* 2008 U.S. Rate*Reduction Pregnancy among sexually active teens % Birth % Abortion % *All rates per 1,000 teens years Secura et al. NEJM 2014.

Pregnancy Rates: Sexually Experienced U.S. Teens Compared to CHOICE Stratified by Race White White Black Black Secura et al. NEJM U.S.CHOICE

The Secret: 3 Key Ingredients Education regarding all methods, especially LARC –Reframe the conversation: start with the most effective methods Access to providers who will offer & provide LARC –Dispel myths and increase the practice of evidence- based medicine Affordable contraception –Institute of Medicine recommendation, Affordable Care Act, Medicaid Expansion, local funders

Thank you

LARC First Resource Center

Can CHOICE Help Shape Policy?

Take-Home Messages CHOICE Methods: –Education, Access, Cost Evidence-based counseling –LARC-friendly providers IUDs rarely contraindicated Same-day insertion

Take-Home Messages LARC Methods are THE most effective –Increased use of LARC will Decrease abortions and unintended pregnancies Decrease racial/SES disparities