Fibroepithelioma of Pinkus (Basal cell carcinoma, fibroepithelioma of Pinkus type) Deba P Sarma, MD Omaha.

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Fibroepithelioma of Pinkus (Basal cell carcinoma, fibroepithelioma of Pinkus type) Deba P Sarma, MD Omaha

M 79, back

Comment First described by Hermann Pinkus in 1953. It is a rare variation of basal cell carcinoma with very indolent clinical course. Unlike other histologic types of basal cell carcinoma, the tumor occurs commonly on the sun-protected skin of trunk, especially back. Presents as a slowly enlarging, fleshy, raised or pedunculated papilloma or achrochordon with a broad base on the trunk or the extremities. Age: Older adults, M=F Histology: Fibroepithelioma of Pinkus shows long, thin, branching and anastomosing strands of basal cell carcinoma within in a fibrovascular stroma. Many strands show a connection with the epidermis. The basaloid strands show two types of cells: a lighter staining cell comprising the bulk of the strand and peripheral, small darker cells showing palisading pattern.

Unusual examples of fibroepithelioma of Pinkus Pan Z, Huynh N, Sarma DP. (2008). Fibroepithelioma of Pinkus in a 9-year-old boy: a case report. Cases Journal 1:21. PMID: 18588684 [PubMed – indexed for MEDLINE] Repertinger SK, Stevens T, Markin N, Klepacz H, Sarma DP.(2008). Fibroepithelioma of Pinkus with pleomorphic epithelial giant cells. Dermatology Online J 14(12):13. [Pubmed- indexed for MEDLINE].