Biology for Future Presidents Important Concepts That Can Be Easily Understood Unless noted, the course materials are licensed under Creative Commons Attribution- NonCommercial-ShareAlike 2.5 Taiwan (CC BY-NC-SA 2.5)Attribution- NonCommercial-ShareAlike 2.5 Taiwan by Professor Larry N. Vanderhoef Chancellor Emeritus & Distinguished Professor University of California, Davis, U.S.A Cancer and HIV A.I.D.S. The Deadliest Cancer Week6 Design courtesy of fppt.com

Frightening Diseases. I. Cancer Causes and Cures

Translating the code in DNA into a protein Jonathan Eisen 3

Watson & Crick Frightening Diseases. I. Cancer Causes and Cures RootsWeb.com 4

Frightening Diseases. I. Cancer Causes and Cures Maurice Wilkins 5

Frightening Diseases. I. Cancer Causes and Cures Rosalind Franklin Science 6 - Rosalind Franklin 08 6

Frightening Diseases. I. Cancer Causes and Cures chemotherapy unnewsJohnnys a big poopy - Uncyclopedia, the content-free encyclopedia Chemotherapy just too expensive to waste on cancer patients anymore - Scrape TV - The World on your side 7

Frightening Diseases. I. Cancer Causes and Cures Radiation Therapy Wikimedia Commons Dina Wakulchik Polemica su radioterapia. Ceccarelli Con il nuovo ospedale nessun miglioramento » La Gazzetta di Lucca 8

Frightening Diseases. I. Cancer Causes and Cures Our Immune System Source: Precision Graphics

Uncontrolled Cell Division, Cancer and Galls

Pancreatic Cancer Pancreatic cancer? Get your affairs in Order. Ehumanbiofield 11

Uncontrolled Cell Division, Cancer and Galls Wikimedia Commons Forest & Kim Starr Flickr plj.johnny Wikimedia Commons Forest & Kim Starr Flickr Gabriela Ruellan Wikimedia Commons Lairich Rig 12

Uncontrolled Cell Division, Cancer and Galls Doing everything you can to extend your life – may not be the best idea. DREAM OF ARLEQUIN 13

Uncontrolled Cell Division, Cancer and Galls Steve Jobs Flickr MATEUS_27:24&25 Scrape TV - The World on your side Flickr MATEUS_27:24&25 14

Uncontrolled Cell Division, Cancer and Galls Genes and Chromosomes Source: National Institute of General Medical Sciences, NIGMS,

Uncontrolled Cell Division, Cancer and Galls University of California, Davis, U.S.A, Larry N. Vanderhoef 16

Uncontrolled Cell Division, Cancer and Galls Source: Cengage Learning - Brooks/Cole 17

Uncontrolled Cell Division, Cancer and Galls Source: Cengage Learning - Brooks/Cole Cell division in plants and animals is virtually identical. 18

Source: Cengage Learning - Brooks/Cole 19

Uncontrolled Cell Division, Cancer and Galls Mouth cancer Thyroid cancer Skin cancer – Basal Cell carcinoma Cancer can appear In any living tissue… SMOKING Tanning Booths Tingkatkan Risiko Kanker Kulit - Jurnal Secience 20

Uncontrolled Cell Division, Cancer and Galls Colon cancer OurAwesomeEssay UNIVERSITAM » Ciencia, Investigación, Tecnología y Desarrollo. 21 ¿Conoces al Virus del Papiloma Humano

Uncontrolled Cell Division, Cancer and Galls Lance Armstrong Testicular cancer Oral cancer Tongue cancer desCrentes zubarica ThePlatform.info 22

Uncontrolled Cell Division, Cancer and Galls Cell structure globalbiology 23

Uncontrolled Cell Division, Cancer and Galls CELL DIVISION Genes are duplicated in the process of cell division Source: Genetics Home Reference 24

Uncontrolled Cell Division, Cancer and Galls Typical cancer More than one mutation is necessary to make a normal cell go cancerous. TipThePlanet 25

Immune System

Source: Finches in Life Book, Life9e-Figure

Immune System Source: Finches in Life Book, Life9e-Figure

Immune System pharmaceuticals shell fish peanuts Common inducers of allergic responses … Patrick M. Gallivan New York State Senate 네이버 블로그 Flickr EuroMagic 29

Immune System mold in a shower dust mites … and some more. Wikimedia Commons Kennyall Quanti di voi hanno problemi di umidità 30

Immune System Poison Ivy Coincidental or evolutionary advantage Source: Public Opinion, Polls and Discussion on SodaHead, sumac-have-you-ever-gotten-it-on-your-skin-whats-the-best-method-of-remedyreli/question /?slide=2http:// sumac-have-you-ever-gotten-it-on-your-skin-whats-the-best-method-of-remedyreli/question /?slide=2 Mankato Free Press Minnesota has always been a small town state - Bluestem Prairie 31

Ranking de ¿Cual Es Tu Mayor Temor - Listas en 20minutos.es Immune System Bees Some people are unusually allergic to bee stings 32

Immune System Pollen – common allergy inducing substance. There’s lots of it for most of the year. Allergy natural treatment | Butterbur, by Société & Vous - Santé 33

Immune System biology111S

Immune System Source: Finches in Life Book, Life9e-Figure

Immune System Source: Diseases and Conditions - A Usermeds.com, Flickr ZenBenjamin Flickr HeatherMG Source: Modern Medical Guide, Source: Pharmaceuticals Drugs,Multimineral Supplement Manufacturers,Antibacterial Drugs Suppliers, Flickr outtacontext 36

Immune System Smallpox Bukisa - Share your Knowledge 37

Immune System Edward Jenner ~

Immune System Milkmaid Cowpox vaccination Jorge Juan Lozano Cámara Source: Milkmaids and Cowpox, The College of Physicians of Philadelphia,

Immune System I Polio Wikispaces Alicia M. 40

Immune System (Conclusion)

Our Immune System Source: Precision Graphics

Immune System (Conclusion) Antibodies this antibody can bind to a type of virus this antibody can bind to a species of bacteria Wikimedia Commons Opabinia regalis 43

dendritic cell naive B cell bacterium complement naive helper T cell antigen- presenting dendritic cell B cell effector helper T cell memory helper T cell memory B cell effector B cell Immune System (Conclusion) Antibody-mediated Immunity University of California, Davis. Larry N. Vanderhoef 44

dendritic cell naive cytotoxic T cell antigen- presenting dendritic cell naive helper T cell activated cytotoxic T cell effector helper T cell memory helper T cell memory cytotoxic T cell effector cytotoxic T cell Immune System (Conclusion) Cell-mediated Immune Response University of California, Davis. Larry N. Vanderhoef 45

cytotoxic T cell cancer cell Immune System (Conclusion) Cellular Immune Response Kills Cancer Cells Flickr Microbe World 46

Human Immunodeficiency Virus and Acquired Immune Deficiency Syndrome Best Compounding Pharmacy Halsted Healthmart HIV Drug Therapy and Treatment Options 47

Immune System (Conclusion) A virus is a noncellular infectious agent. It consists of a protein coat wrapped around genetic material (either RNA or DNA) and a few viral enzymes. A virus is far smaller than any cell and does not have ribosomes or other metabolic machinery. To replicate, the virus must insert its genetic material into a cell of a specific organism, which we call its host. A viral infection is like a cellular hijacking. Viral genes take over a host cell’s machinery and direct it to synthesize viral proteins and nucleic acids. These components then self-assemble as new viral particles. 48

Immune System (Conclusion) protein subunits of coat RNAviral DNA and enzymes lipid envelope with protein components protein coat Inside the envelope Wikimedia Commons GrahamColm Wikimedia Commons Gleiberg Flickr Microbe World 49

Immune System (Conclusion) Wikimedia Commons Daniel Beyer 50

Immune System (Conclusion) Source: Finches in Life Book, Life9e-Figure

Immune System (Conclusion) Wikimedia Commons M. Sand, D. Sand, C. Thrandorf, V. Paech, P. Altmeyer, F. G. Bechara Case study in dentistry – Lines Source: MedlinePlus

Immune System (Conclusion) Rock Hudson 11/17/25 – 10/2/85 Journal - Journal on open sea and coastal kayak paddling Listas creadas por los usuarios de 20minutos.es 53

Immune System (Conclusion) HIV AIDS 54

Immune System (Conclusion) Source: Michigan Department of Community Health, Bureau of Epidemiology, HIV/AIDS Surveillance Section; reported cases as of July 1, 2006,

Immune System (Conclusion) 56

The A.I.D.S. “cocktail” -inhibit binding to host cell -slow transcription of RNA -inhibit integration of viral DNA into the human chromosome -prevent processing of newly translated polypeptides into viral proteins Immune System (Conclusion) 57

Immune System (Conclusion) Source: Finches in Life Book, Life9e-Figure

Immune System (Conclusion) Transmission activities Sex – Anal, vaginal, oral Blood transfusion Dirty needles Fluid exchanges between mother and baby during pregnancy Breast feeding Child birth 59

Immune System (Conclusion) million people living with HIV/AIDS 2.6 million new infections per year 1.8 million deaths per year. About 75% in subsaharan Africa 60

Immune System (Conclusion) NO KNOWN CURE 61

Immune System (Conclusion) Wikipedia Many cancers Fevers and sweats Pneumonia TB Problems in bone marrow, gastrointestinal tract, lymph nodes, CNS Dementia Bipolar disorder ETC., ETC. Everything that can go wrong – eventually DOES 62

WorkLicenseAuthor/Source Jonathan Eisen /12/31 visited RootsWeb.com /5/28 visited Wikimedia Commons: Author Unknown /5/28 visited Science 6 - Rosalind Franklin /5/28 visited unnewsJohnnys a big poopy - Uncyclopedia, the content-free encyclopedia /5/28 visited Copyright Declaration 63

WorkLicenseAuthor/Source Wikimedia Commons Unknown photographer/artist, National Cancer Institute /12/31 visited Chemotherapy just too expensive to waste on cancer patients anymore - Scrape TV - The World on your side to-cancer-patients-anymore-Scrape-TV%20The-World-on-your-side html 2012/5/28 visited Wikimedia Commons Dina Wakulchik =zh-tw 2011/12/31 visited Polemica su radioterapia. Ceccarelli Con il nuovo ospedale nessun miglioramento » La Gazzetta di Lucca dell-udc-con-il-nuovo-ospedale-nessun-miglioramento/ 2012/5/28 visited This work originally comes from Precision Graphics + and it is used and modified subject to the fair use doctrine in accordance with: Taiwan Copyright Act Articles 52 & 65 term of use The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Act OCW-Oct29.pdf Copyright Declaration 64

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WorkLicenseAuthor/Source Wikimedia Commons Lairich Rig _ jpg 2012/1/13 visited This work is from Prensa Rosa wikiNoticia + swazye and used subject to the fair use doctrine in accordance with: swazye Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Act OCW-Oct29.pdf DREAM OF ARLEQUIN /5/4 visited Flickr MATEUS_27:24& /1/14 visited Scrape TV - The World on your side may-be-the-next-to-get-fired-cancer-die-young-Scrape-TV-The-World-on-your- side.html 2012/5/4 visited Copyright Declaration 66

WorkLicenseAuthor/Source Flickr MATEUS_27:24& /1/14 visited This work is from National Institute of General Medical Sciences, NIGMS, and used subject to the fair use doctrine in accordance with: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Act OCW-Oct29.pdf University of California, Davis, U.S.A, Larry N. Vanderhoef This work originally comes from Cengage Learning - Brooks/Cole and used subject to the fair use doctrine in accordance with: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Act OCW-Oct29.pdf This work originally comes from Cengage Learning - Brooks/Cole and used subject to the fair use doctrine in accordance with: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Act OCW-Oct29.pdf Copyright Declaration 67

WorkLicenseAuthor/Source This work originally comes from Cengage Learning - Brooks/Cole and used subject to the fair use doctrine in accordance with: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Act OCW-Oct29.pdf SMOKING /1/14 visited Wikimedia Commons: Author Unknown /1/14 visited Tanning Booths Tingkatkan Risiko Kanker Kulit - Jurnal Secience kanker.html 2012/1/14 visited ¿Conoces al Virus del Papiloma Humano /11/1 visited Copyright Declaration 68

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WorkLicenseAuthor/Source This work is from Modern Medical Guide, used subject to the fair use doctrine in accordance with: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Act. Flickr HeatherMG /1/13 visited This work is from Pharmaceuticals Drugs,Multimineral Supplement Manufacturers,Antibacterial Drugs Suppliers, and used subject to the fair use doctrine in accordance with: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Act. Bukisa - Share your Knowledge /5/3 visited Wikimedia Commons CDC/James Hicks /1/13 visited Copyright Declaration 74

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WorkLicenseAuthor/Source Wikimedia Commons Daniel Beyer /5/29 visited This work is from Finches in Life Book, Life9e-Figure and used subject to the fair use doctrine of: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Acthttp:// 305-OCW-Oct29.pdf This work is from MedlinePlus + and used subject to the fair use doctrine of: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Acthttp:// 305-OCW-Oct29.pdf Wikipedia: Author Unknown /12/28 visited Case study in dentistry – Lines /5/29 visited Copyright Declaration 78

WorkLicenseAuthor/Source Wikimedia Commons M. Sand, D. Sand, C. Thrandorf, V. Paech, P. Altmeyer, F. G. Bechara /12/31 visited Wikimedia Commons McLeod g&oldid= /12/31 visited Journal - Journal on open sea and coastal kayak paddling muse-gets-home.html 2012/5/29 visited Listas creadas por los usuarios de 20minutos.es / 2012/5/29 visited This work is from Rock Hudson - History Commons + and used subject to the fair use doctrine of: Taiwan Copyright Act Articles 52 & 65 The "Code of Best Practices in Fair Use for OpenCourseWare 2009 ( 305-OCW-Oct29.pdf)" by A Committee of Practitioners of OpenCourseWare in the U.S. The contents are based on Section 107 of the 1976 U.S. Copyright Acthttp:// 305-OCW-Oct29.pdf Copyright Declaration 79

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