H1N1 virus -update Dr Anna Sharma MBBS MSc MRCP(paeds) FRCPCH Consultant paediatrician Immunisation clinical lead- Hillingdon PCT

Flu pandemics Name Year Deaths (millions) Subtype Russian Flu possibly H2N2H2N2 Spanish Flu (?)H1N1Spanish FluH1N1 Asian Flu H2N2Asian FluH2N2 Hong Kong Flu H3N2Hong Kong FluH3N2 New Jersey Flu1976H1N1 Swine Flu H1N1Swine FluH1N1

2009/10 H1N1 pandemic

UK mortality 1918 figure taken from Center for Disease Control and Prevention USA

2009/2010 pandemic

epidemic-comparision of age profile with 1917 seasonal flu age profile

Age distribution of swine flu hospitalisations in UK to date

Vaccine uptake Uptake in 2008/9 –74.1% in over 65’s –47.1% in clinical risk groups under 65 –16.5% in Staff nationally –WHO target is 75% Uptake in 2009/2010 –70% seasonal flu 30% over 65’s H1N1 –27% under 65s H1N1 –16.8% under 5s H1N1 –70% of GPs –57% of all HCW staff –DH target is 51%

Clinical risk groups

Definition of ‘High risk’ groups Immunosuppressed Long term respiratory illness Long term renal illness

Clinical risk groups-contd

Under fives extension Runs from 8 th Dec 2009 to 31 st March 2010 All children over 6 months and under 5 years Dob range 8 th Jun 2004 to 31 st October 2009

Vaccines and doses Preferred: GSK Pandemrix One dose of 0.25ml for those under 9y unless immunosuppressed Optional for egg allergy/mothers preference: Baxter Celvapan Two doses of 0.5 ml for all ages: three weeks between each dose

Vaccine safety? 3.2 million doses of vaccine given 214,000 children 132,000 pregnant women (1 in 5) 387,000 health care workers No major side effects »Data as of 22 Jan 2010 UK

A very big Thank you To all Hillingdon’s Family doctors Practice nurses Practice managers Practice support staff –Who have risen to the occasion magnificently

Keep it up till March ‘When the virus returns in the 2010 flu season those who die will do so from a vaccine preventable disease’ Chief Medical Officer Jan