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UMELISA  Birth defects Down syndrome Congenital hypothyroidism Phenylketonuria Biotinidase deficiency HIV 1+2 Hepatitis B Hepatitis C HTLV I +II Chagas disease Dengue Leprosy Tetanus Toxoplasmosis Allergy

NATIONAL SCREENING AND OTHER SPECIAL PROGRAMS IN CUBA Mother - ChildMother - Child Blood CertificationBlood Certification Epidemiological SurveillanceEpidemiological Surveillance Placenta CertificationPlacenta Certification Minimum access neurosurgeryMinimum access neurosurgery

Severe Birth Defects HIV Hepatitis B Hepatitis C Congenital Hypothyroidism Phenilketonuria Biotinidase Def. (2002) Galactosemia (2002) Congenital Adrenal H. (2003) Others

CUBAN PRENATAL PROGRAMS RESULTS. Pregnants Screened: Pregnants Screened: Birth Defects Detected: Birth Defects Detected: Cuba 1986 – 2001 Only 1 mother to child HIV transmission since 1997 Only 1 mother to child HIV transmission since 1997 No mother to child HBV transmission in 95% No mother to child HBV transmission in 95% 2.08 x 1000

CONGENITAL HYPOTHYROIDISM CUBAN SCREENING PROGRAM. Newborns Screened: Newborns Screened: Hypothyroidism: 641 Hypothyroidism: 641 Permanent: 325 Permanent: 325 Transitory: 203 Transitory: 203 Under study: 113 Under study: 113 Incidence: 1 : 3295 Cuba 1986 –

BLOOD CERTIFICATION AND SEROLOGICAL SURVEILLANCE HIV1+2, HBsAg, HCV, DENGUE, CHAGAS 17,824,040 UMELISA 13,568,060 7,314,844

WHO HIV SCREENING ALGORITHM

VIH 1 and VIH 2 cases detected More than 20 million tested VIH 1 VIH 2 Year Seropositives DAVIH SUMA DETECTED 4072 LIVING WITH HIV/AIDS 3022