Department of Health and Human Services National Institutes of Health National Center for Research Resources Division of Research Infrastructure Extending the Reach of Advanced Networking: Two Pilot Projects at the NCRR Susan R. Kayar, Ph.D. Shelia A. McClure, Ph.D.

Institutional Development Award (IDeA)/DRI Designed to enhance the competitiveness for biomedical research funding of institutions located in states with historically low funding from NIH. Designed to enhance the competitiveness for biomedical research funding of institutions located in states with historically low funding from NIH. Inclusion of underserved populations is a primary feature. Inclusion of underserved populations is a primary feature. Research focus is broad. Research focus is broad.

Eligible States 23 States and Puerto Rico

How is the Internet used at IDeA-Funded Institutions? Communications Communications  and basic computer services  Library access  Website design and utilization  Video teleconferencing Genomics and Proteomics data management Genomics and Proteomics data management Imaging Imaging Equipment linking and collaboratories Equipment linking and collaboratories Data Mining Data Mining Computing at high speed, high capacity Computing at high speed, high capacity Archiving of databases Archiving of databases

“IDeANet” Project Increased connectivity for high-bandwidth science applications in six western IDeA states is first step. Increased connectivity for high-bandwidth science applications in six western IDeA states is first step. * * * * * *

Geographic Reality of Western Region IDeANet

Internet2 – ‘Abilene’ 10gb/s Upgrade

Connections to Backbone U. Idaho U. Wyoming PNWGP U. Nevada Reno Montana State U CENIC FRGP U. Hawaii U. Alaska

Multiple Levels of Benefit IDeANet will relieve strategic bottlenecks in connectivity entering states. IDeANet will relieve strategic bottlenecks in connectivity entering states. One major university campus per state to be directly linked. One major university campus per state to be directly linked. In general, connectivity of on-campus and in- state networks is relatively high. In general, connectivity of on-campus and in- state networks is relatively high. Many sites throughout states will experience improved Internet performance. Many sites throughout states will experience improved Internet performance. Can leverage benefits to other university departments and other institutions. Can leverage benefits to other university departments and other institutions.

Additional Institutional Needs End-to-end performance evaluation at all sites; Before/after performance metrics; Assessment of needs for computer configurations, software, etc.; Address IT personnel issues (‘wizard gap’); Assess opportunities for achieving better connectivity to other institutions in each state.

Research Centers in Minority Institutions (RCMI) Designed to expand the Nation’s capacity for conducting biomedical research at institutions with 50% or greater enrollment of underrepresented minorities that grant doctoral degrees in health/health-related sciences; Designed to expand the Nation’s capacity for conducting biomedical research at institutions with 50% or greater enrollment of underrepresented minorities that grant doctoral degrees in health/health-related sciences; Strengthen research environments and improve faculty research competitiveness; Strengthen research environments and improve faculty research competitiveness; Enhance the clinical research capacity Enhance the clinical research capacity

How is the Internet used at RCMI Institutions ? All the usual academic uses All the usual academic uses Research training and faculty development Research training and faculty development Bioinformatics and computational biology Bioinformatics and computational biology Research networks on health disparities Research networks on health disparities Global collaborations Global collaborations

RCMI Translational Research Network (RTRN) Goals: Establish a stable high performance network linking RCMI sites and other sites (using Internet2 Abilene infrastructure) Establish a stable high performance network linking RCMI sites and other sites (using Internet2 Abilene infrastructure) Establish distributed and linked data collections for the test bed clinical research projects Establish distributed and linked data collections for the test bed clinical research projects Enable data mining from multiple data collections or databases Enable data mining from multiple data collections or databases Develop a stable software and hardware infrastructure with partnering groups that will allow centers to coordinate efforts to accumulate larger studies than can be carried out at one site Develop a stable software and hardware infrastructure with partnering groups that will allow centers to coordinate efforts to accumulate larger studies than can be carried out at one site

RCMI Translational Research Network (RTRN) The RTRN will include: Consortium of clinical investigators from the RCMI Clinical Research Centers; Consortium of clinical investigators from the RCMI Clinical Research Centers; Translational and clinical investigators from other RCMI institutions as appropriate for studies; Translational and clinical investigators from other RCMI institutions as appropriate for studies; Other NIH-supported Clinical Research Centers; Other NIH-supported Clinical Research Centers; Other relevant organizations, including patient support organizations, for the study of a subgroup of diseases; and Other relevant organizations, including patient support organizations, for the study of a subgroup of diseases; and Data and Technology Coordinating Center (DTCC) Data and Technology Coordinating Center (DTCC)

RTRN - DTCC The DTCC will provide : Scalable coordinated clinical data management system for collection, storage, and analysis of data of the RTRN Scalable coordinated clinical data management system for collection, storage, and analysis of data of the RTRN Portal and tools for integration of developed and publicly available datasets for data mining at RCMI Centers Portal and tools for integration of developed and publicly available datasets for data mining at RCMI Centers Web based recruitment and referral Web based recruitment and referral User friendly resource site for the public, research scientists, and clinicians User friendly resource site for the public, research scientists, and clinicians

RTRN This cooperative program should: facilitate identification of biomarkers for disease risk, disease severity/activity, and clinical outcomes facilitate identification of biomarkers for disease risk, disease severity/activity, and clinical outcomes encourage development of new approaches to diagnosis, prevention, and treatment of those diseases that disproportionately affect minority populations encourage development of new approaches to diagnosis, prevention, and treatment of those diseases that disproportionately affect minority populations