Lecture 16 Get Lecture Problem 6 The Synthetics This Week in Lab:

Slides:

Advertisements

Similar presentations

CHAPTER 15 CONCURRENT ENROLLMENT. CARBOXYLIC ACID CCCCarboxylic acid or carboxyl group - is an organic compound that contains the following functional.

Advertisements

Carboxylic Anhydrides, Esters and Amides. Naming Anhydrides Drop the word acid and say anhydride.

Chapter Seventeen Carboxylic Acids and Their Derivatives Fundamentals of General, Organic & Biological Chemistry 4th Edition Mohammed Hashmat Ali Southeast.

162 Chapter 19: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution 19.1: Nomenclature of Carboxylic Acid Derivatives (please read)

Carboxylic acids - Nucleofilic acyl substitution reaction Dr AKM Shafiqul Islam School of Bioprocess Engineering.

Revision of Formation of Esters Formed from:- Formed from:- Carboxylic Acid Carboxylic Acid.

THE SOLVENTLESS ALDOL-TYPE CONDENSATION

191 Chapter 21: Ester Enolates 21.1: Ester  Hydrogens and Their pK a ’s. The  -protons of esters are less acidic that ketones and aldehydes. Typical.

Ch Lect. 2 Carboxylic Acids and Derivatives I.Alkanoyl Halides A.Preparation 1)Inorganic esters utilized, just as in conversion of alcohols to alkyl.

Lecture 11/17/07 CHE132: General Chemistry II Dr. Jimmy Hauri.

Questions of the Day: a) Diels-Alder reactions are what type of reactions? b) Which structural feature is always formed as the result of Diels-Alder reactions?

Today, 9/30: “Esterification” Grignard reactions Next Tuesday, 10/7: Conclusion of Grignard. Following Tuesday 10/14: Practice. Introduction to Unknowns.

REVISED Propose structure C 4 H 8 O 3 NMR 2.62 (t,2H) 3.38 (s, 3H) 3.68 (t,2H) 11.5 (s, 1H)

A) Write the structure of the radical formed when Br. radical reacts with ethyl benzene. b) Why is there no radical formation in the beta position of ethyl.

Esters of Carboxylic Acids 17.5 Naming Esters 17.6 Properties of Esters Chapter 17 Carboxylic Acids And Esters.

165 Chapter 20: Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution 20.1: Nomenclature of Carboxylic Acid Derivatives (please read)

Carboxylic Acid Derivatives Acid Chlorides Acid Anhydrides Esters Amides Nitriles Nucleophilic Acyl Substitution.

ESTERS: SYNTHESIS AND FRAGRANCE

Higher Chemistry Unit 2 Multiple Choice Questions Section 6 Esters

Organic Chemistry Lesson # 3 – Functional Group Reactions.

Aim: What are functional groups?. Isomers Compounds that have the same molecular formula but have different structural formulas and different names; isomers.

Experiment 21: ESTERS: SYNTHESIS AND FRAGRANCE Objectives:  To synthesize an ester from acetic acid with isoamyl alcohol under reflux.  To purify your.

17.CARBOXYLIC ACIDS AND DERIVATIVES. ( approx. lecture time: 4 lectures) Topics covered: A-I, , Some important carboxylic acids.

Drug Notes Health. Terms Tolerance -- Resistance to a poison The capacity to absorb a drug continuously in large doses without negative effect Withdrawal.

LIDOCANE TOPICAL LIDODERM, AKA ANECREAM, BACTINE, LIDOCREAM.

Chapter 14 – From Organic Molecules to Medicines.

Biological Chemistry FIRST YEAR ORGANIC CHEMISTRY Lecture Eight Carboxylic acids + Esters Convenor : Dr. Fawaz Aldabbagh.

Chapter 40 Esterification. Synthesis of n-Butyl Ester of Unknown Acid by Azeotropic Distillation of Water.

Lecture 17 Hand in Lecture Problem 6 The Synthetics Quiz 6 Review Reminder: Quiz 6 in lecture on Thursday & Hand in Selection Sheet! This Week in Lab:

Lecture 15 Get Lecture Problem 5 Due The Synthetics This Week in Lab: Ch 9 PreLab Due Quiz 5 Ch 6 Final Report Due Next Week: Spring Break!!!

Reactions of Carboxylic Acids, Carboxylate Salts, and Carboxylate Esters Susan F. Hornbuckle Associate Professor of Chemistry Clayton State University.

Carboxylic Acid Derivatives: Nucleophilic Acyl Substitution

Carboxylic Acids Carboxylic acids contain a carboxyl group: O CH 3 C-O-H ORCH 3 CO 2 H Carboxyl group.

Alcohols. Complete Combustion of Alcohols IB Chemistry SL CC23E83D555 Oxidation reactions.

Esters C.I What are they? How are they made? Formed when an alcohol reacts with a carboxylic acid. Very slow reaction, unless! an acid catalyst.

1 Carboxylic Acid Derivatives. 2 Phosphate Nomenclature.

Higher Chemistry Unit 2 Section 6 - Esters Multiple Choice Questions This is designed to be used by teachers to help students develop skills in answering.

Lecture 11 IR Theory Next Class: Lecture Problem 4 due Thin-Layer Chromatography This Week In Lab: Ch 6: Procedures 2 & 3 Procedure 4 (outside of lab)

D.3.2 Describe the use of derivatives of salicylic acid as mild analgesics and compare the advantages and disadvantages of using aspirin and paracetamol.

Carboxylic acids and their derivatives. Required background: Aldehydes, ketones Acidity of alcohols Reaction mechanisms Essential for: Aminoacids, peptides.

Formation of the ester ethyl propanoate from a carboxylic acid

Esters and Esterification. Esters produced by combining carboxylic acid and alcohol (esterification) Large chain esters account for flavor and odor.

Week 4 © Pearson Education Ltd 2009 This document may have been altered from the original Explain the water solubility of carboxylic acids. Describe the.

Preparation and Examination of Aspirin

Carboxyl Derivatives In this chapter, we study three classes of compounds derived from carboxylic acids; anhydrides, esters, and amides. Each is related.

Chem 341 Review for Finals Structure Determination NMR –Chemical shifts, splitting patterns, integrations IR –ROH, C=O Formula => # of Rings + Pi-Bonds.

+ +. After completing this topic you should be able to : State esters are formed by the condensation reaction between an alkanoic acid and an alcohol.

PREPARATION OF ACIDS CARBONYLATION OF ORGANOMETALLICS.

Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. Chapter 13 Lecture Outline Prepared by Jennifer N. Robertson-Honecker.

Chemical department O.C.U.P.

Hydrolysis of Acid Derivatives

Drill: Draw & Name Reactants & Products of:

The Reaction between a Carboxylic acid and an Alcohol-Esterification

Ch 17- Carboxylic Acids and their derivatives

Aspirin Chapter 14.

Lecture 33 – Chapter 20 : Ester Hydrolysis

Lecture 29 Hand in LP 9/10 Quiz 8 Review Course evaluation

Natural Products Nomenclature Acidity Preparation Reactions

Lecture 10 IR Theory This Week In Lab: Ch 6 PreLab Due

Natural Products Nomenclature Acidity Preparation Reactions

Figure 16.3 Some general reactions of carboxylic acid derivatives.

Esterification.

Synthesis of biodiesel

Condensation Reactions

EXP.NO 4 :- Synthesis of Aspirin IUPAC Name 2-acetyloxybenzoic acid

Chapter 40 Esterification. Synthesis of n-Butyl Acetate by Azeotropic Distillation of Water.

Synthesis of salicylic acid

Name Reactions B.Sc.II P-V By N. M.Gosavi.

Ch Lect. 2 Carboxylic Acids and Derivatives

Tajamul Ahmad Bhat Assistant Lecturer Department of Chemistry

Presentation transcript:

Lecture 16 Get Lecture Problem 6 The Synthetics This Week in Lab: Ch 9 PreLab Due Quiz 5 Ch 6 Final Report Due Next Week: Spring Break!!!

The Condensation Reactions Experiment 14: Synthesis of 3-Carbethoxycoumarin Go over mechanisms for transesterifcation & aldol condensation in class

The Condensation Reactions Experiment 16: Synthesis of Creatine Go over mechanism in class.

Esterification Synthesis of esters A Typical Esterification (generic example): reaction of a carboxylic acid (elec) with an alcohol (nuc) acid catalyzed reversible known as a Fisher Esterification

Esterification Experiment 80: Synthesis of Aspirin Reaction of an alcohol (nuc) with an anhydride (elec) Similar mechanism to Fisher esterification Analyses: IR & NMR Aspirin: Anti-inflammatory analgesic (pain killer) Antipyretic (fever reducer)

More Esterifications Experiment 86: Synthesis of Benzocaine Fisher esterification reaction Analyses: IR, NMR & MS Benzocaine: Topical local anesthetic for itching and pain caused by sunburn, insect bites, poison ivy, poison oak, minor cuts Deadens the nerve endings in the skin

Fragrant Esters Analyses: IR, NMR, GC, GC-MS, MS