Bioactive ceramic-reinforced composites for bone augmentation by K. E. Tanner Interface Volume 7(Suppl 5):S541-S557 October 6, 2010 ©2010 by The Royal.

Slides:



Advertisements
Similar presentations
2E4: SOLIDS & STRUCTURES Lecture 9
Advertisements

In-Class Case Study: Determining the Mechanical Properties of Bone Using State-of-the-art Mechanical Testing System (MTS Bionix) Prepared by Prof. Deepak.
Dr. HABEEB HATTAB HABEEB Office: BN-Block, Level-3, Room Ext. No.: 7292 Lecturer: Dr. HABEEB ALANI.
MECHANICAL PROPERTIES
Mechanics of Materials – MAE 243 (Section 002) Spring 2008 Dr. Konstantinos A. Sierros.
Normal Strain and Stress
TensiNet Symposium SOFIA 2010 – Tensile Architecture: Connecting Past and Future September 2010, Sofia, Bulgaria Biaxial testing of architectural.
Chapter 7 Mechanical Properties of Solids.
Sample Problem 4.2 SOLUTION:
Stress and Strain. Solid Deformation  Solids deform when they are subject to forces. Compressed, stretched, bent, twistedCompressed, stretched, bent,
Ceramic microparticles and capsules via microfluidic processing of a preceramic polymer by Congwang Ye, Anthony Chen, Paolo Colombo, and Carlos Martinez.
Designing for Stiffness
The role of delamination in failure of fibre-reinforced composites by M. R. Wisnom Philosophical Transactions A Volume 370(1965): April 28, 2012.
Modeling of CNT based composites: Numerical Issues
Interfacial and biological properties of the gradient coating on polyamide substrate for bone substitute by Di Huang, Lulu Niu, Yan Wei, Meiqing Guo, Yi.
CHAPTER 7: MECHANICAL PROPERTIES
Tensile Test The most common static test is the uniaxial tensile test, which provides information about a variety of properties. As a load is applied to.
Mechanical Properties of
by Michael J. Kendall, and Clive R. Siviour
Mechanical characterization of lead- free solder joints J. Cugnoni*, A. Mellal*, Th. J. Pr. J. Botsis* * LMAF / EPFL EMPA Switzerland.
Sample Problem 4.2 SOLUTION:
Strength of Material Shear Strain Dr. Attaullah Shah.
Chapter 6: Mechanical Properties
Mechanical Properties
Effective Inelastic Response of Polymer Composites by Direct Numerical Simulations A. Amine Benzerga Aerospace Engineering, Texas A&M University With:
CHAPTER 6: MECHANICAL PROPERTIES
FYI: All three types of stress are measured in newtons / meter2 but all have different effects on solids. Materials Solids are often placed under stress.
Variability in, and property prediction for, natural fibre composites John Summerscales (PU), Amandeep Virk (GU) and Wayne Hall (GU)
Polyurethane-based scaffolds for myocardial tissue engineering by Valeria Chiono, Pamela Mozetic, Monica Boffito, Susanna Sartori, Emilia Gioffredi, Antonella.
Unit V Lecturer11 LECTURE-I  Introduction  Some important definitions  Stress-strain relation for different engineering materials.
Towards a model-based integration of co-registered electroencephalography/functional magnetic resonance imaging data with realistic neural population meshes.
ENGR-45_Lec-14_Metal_MechProp-1.ppt 1 Bruce Mayer, PE Engineering-45: Materials of Engineering Bruce Mayer, PE Registered Electrical.
 Stress has units: N/m 2 or lb f /in 2 Engineering Stress Shear stress,  : Area, A F t F t F s F F F s  = F s A o Tensile stress,  : original area.
1 ME383 Modern Manufacturing Practices Lecture Note #3 Stress-Strain & Yield Criteria Dr. Y.B. Guo Mechanical Engineering The University of Alabama.
Affordable Bio-polymer Matrix Composites for Lightweight Vehicular Structures Automotive News Conference June 13-15, 2005 Wynfrey Hotel, Birmingham, AL.
Welding Design 1998/MJ1/MatJoin2/1 Design. Lesson Objectives When you finish this lesson you will understand: Mechanical and Physical Properties (structure.
MECHANICAL TESTING.
Measurement of the mechanical properties of granular packs by wavelength-scanning interferometry by Yanzhou Zhou, Ricky D. Wildman, and Jonathan M. Huntley.
Electrophoretic deposition of biomaterials by A. R. Boccaccini, S. Keim, R. Ma, Y. Li, and I. Zhitomirsky Interface Volume 7(Suppl 5):S581-S613 October.
Subject: Composite Materials Science and Engineering Subject code:
Machine Design I (MCE-C 203) Mechatronics Dept., Faculty of Engineering, Fayoum University Dr. Ahmed Salah Abou Taleb Lecturer, Mechanical Engineering.
CONSTRUCTION MATERIALS
Chapter 2 Properties of Metals.
Chapter 9: Mechanical Properties of Matter
Polymer Properties Exercise 4.
1 MFGT 104 Materials and Quality Compression, Shear, Flexural, Impact Testing Professor Joe Greene CSU, CHICO.
Fatigue 7-1. Fatigue of Metals Metals often fail at much lower stress at cyclic loading compared to static loading. Crack nucleates at region of stress.
Date of download: 5/29/2016 Copyright © ASME. All rights reserved. From: Quantification of Foreign Object Damage and Electrical Resistivity for Ceramic.
Mechanics of Bone BME 615.
Date of download: 5/30/2016 Copyright © ASME. All rights reserved. The Rate (Time)-Dependent Mechanical Behavior of the PMR-15 Thermoset Polymer at Temperatures.
Chapter Objectives Understand how to measure the stress and strain through experiments Correlate the behavior of some engineering materials to the stress-strain.
Date of download: 6/6/2016 Copyright © ASME. All rights reserved. From: A Comprehensive Parametric Finite Element Study on the Development of Strain Concentration.
Date of download: 6/22/2016 Copyright © ASME. All rights reserved. From: The Importance of Intrinsic Damage Properties to Bone Fragility: A Finite Element.
Polymer Properties Exercise 4.
Failure of epoxy resins
GOVERMENT ENGINEERING COLLEGE BHUJ (CIVIL ENGINEERING)
Computational Prediction of Mechanical Performance of Particulate-Reinforced Al Metal-Matrix Composites (MMCs) using a XFEM Approach Emily A. Gerstein.
A. K. Mallik and D. Basu Central Glass and Ceramic Research Institute, Kolkata Effect of processing technologies on grain size and mechanical properties.
Presentation By: Assist. Prof. Dr. Jawad K. Oleiwi
Dan Meng, C.K. Lee, Y.X. Zhang*
Direct and Bending Stresses
Elasticity and Viscoelasticity
Mechanics of Materials Dr. Konstantinos A. Sierros
Date of download: 12/27/2017 Copyright © ASME. All rights reserved.
Lecture 9 – Deformation and Damage
LECTURE-I Introduction Some important definitions
Lecture 9 – Deformation and Damage
Elastic & Plastic behavior of Materials
Opposing cartilages in the patellofemoral joint adapt differently to long-term cruciate deficiency: chondrocyte deformation and reorientation with compression 
Hung-Yu Chang, Xuejin Li, George Em Karniadakis  Biophysical Journal 
Presentation transcript:

Bioactive ceramic-reinforced composites for bone augmentation by K. E. Tanner Interface Volume 7(Suppl 5):S541-S557 October 6, 2010 ©2010 by The Royal Society

Apparent shear viscosity of molecular weight PE reinforced with 40 vol% spray-dried HA (P205) and sintered HA particles (P215) at temperatures between 200 and 250°C (adapted from Joseph et al. 2002a). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Schematic showing the different amounts of matrix used to coat high specific surface area spray-dried HA (P205) versus sintered low specific surface area HA (P215S) (adapted from Joseph et al. 2002a). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Impact fracture surfaces of 30 vol% (a) spray-dried HA and (b) sintered HA in polyethylene, showing the longer draw fibrils with the lower surface area filler particles (marker bars = 10 µm) (adapted from Zhang & Tanner 2008). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Effect of the extrusion ratio on the flexural strength (crosses), flexural modulus (open squares) and strain to failure (filled triangles) of hydrostatically extruded 40 vol% HA/PE. K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Optical micrographs of selectively laser-sintered 20 vol% HA in PE showing the infiltration of the resin and thus that it is an open-celled material with each particle composed of HA/PE composite (marker bars are 50, 50 and 10 µm, respectively) (adapted fro... K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Isochronous creep testing of HAPEX showing (a) the loading regime and (b) the results obtained for high-density polyethylene (HDPE) and reinforced with 20 vol% (20 HA/PE) and 40 vol% HA (40 HA/PE) (adapted from Suwanprateeb et al. 1995). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

(a) Influence of immersion upon the creep behaviour of 2.5 Mrad γ-irradiated 40 HA/PE at 6 MPa applied stress at 37°C in Ringer's solution (continuous line, non-immersed; dash–dot line, 1 day; short-dashed line, 7 days; dotted line, 90 days; long-dashed lin... K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Stress–strain loops for fully reversed (a) tension compression at ±50% of ultimate tensile strength and (b) torsion at ±50% of ultimate shear strength (adapted from Ton That et al. 2000a). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

(a) Comparison of the Young modulus of HA in PE measured experimentally (filled squares) and predicted using FEA modelling with the PE bulk modulus at 5 GPa (circles) and 10 GPa (open squares); (b) contours of stress concentration of the von Mises stress in... K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

(a) Alkaline phosphatase activity on samples of HAPEX (filled bars) and PE (striped bars) with Thermanox (TMX) (unfilled bars) as a control surface and (b) SEM of osteoblasts attaching down onto the HA particles in HAPEX (marker bar = 10 µm) (adapted from H... K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Effect of surface texture on osteoblast attachment to (a) grooved with grooves 50 µm deep and 50 µm wide and (b) pitted with pits 50 µm deep and 50 µm wide and polished areas of HAPEX (marker bars = 100 µm) (adapted from Rea et al. 2004c). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

The interaction of femoral head origin osteoblasts with 30 vol% HA/PE manufactured using (a) spray-dried HA, (b) sintered HA particles (marker bars = 10 µm) and (c) the alkaline phosphatase activity of osteoblasts from femoral heads (HOBf) and calvaris (HOB... K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

The interaction of human osteoblasts on selectively laser-sintered (a) 20 vol% HA/PA; (b) 30 vol% HA/PA (marker bars = 10 µm) and (c) osteocalcin levels on Thermanox control (TMX, unfilled bars), electively laser-sintered 20 vol% HA/PA (SLSHAPE, grey bars)... K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Section through the base of the slot machined into a HAPEX cylinder and implanted in a rabbit knee for five weeks. K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

A HAPEX implant in the orbital floor of a patient who has lost an eye. K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Middle ear implant in situ showing the notch cut in the HAPEX shaft to allow the implant to sit over the arch of the stapes (top) and the HA head resting on the tympanic membrane (bottom). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Actin cytoskeleton (green)/vinculin (red) interaction surrounding the cell nucleus (blue) on (a) PMMA (marker bar = 10 µm) and (b) PMMA reinforced with 6 vol% HA (marker bar = 10 µm) (adapted from Dalby et al. 2001). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Interface developed between cortical bone and 40 vol% HA/PHB after one month (marker bar = 100 µm) (adapted from Luklinska & Bonfield 1997). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Comparison of the reinforcing effects of hydroxyapatite (HA) (filled diamonds), Bioglass (filled squares) and A–W glass (filled triangles) ceramic in polyethylene on (a) Young's modulus and (b) tensile strength at a range of volume fractions. K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

Polished sections of 40 vol% Bioglass-reinforced PE. (a) Polished section (marker bar = 100 µm) and (b) after 7 days in simulated body fluid (marker bar = 10 µm) (adapted from Huang et al. 1997a). K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society

(a) An osteoblast growing on A–W glass ceramic in PE composite showing the cell attaching preferentially onto the A–W glass ceramic particles (marker bar = 10 µm) and (b) the increases in cell number with time for 30 and 50 vol% A–W glass ceramic in PE with... K. E. Tanner J. R. Soc. Interface 2010;7:S541-S557 ©2010 by The Royal Society