Bone Mineral Density and Fracture. The Plot Thickens: The Bones Thin.

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Presentation transcript:

Bone Mineral Density and Fracture

The Plot Thickens: The Bones Thin

New Use(s)? Thigh bone connected to the blood stream Flexibility, strength and balance Custom models

Both Ends against the Middle Argument for Impact: Mechanical stress activates osteocytes Argument against Impact: Trauma initiates chondral degeneration

Osteoporosis and Osteoarthritis Osteoarthritis Impact a must. –Mechanoreceptors: Impact a must. Osteoporosis No Impact. –Chondral Damage: No Impact.

Osteoporosis vs Osteoarthritis Osteoarthritis Impact a must. –Mechanoreceptors: Impact a must. Osteoporosis No Impact. –Chondral Damage: No Impact.

Osteoporosis and Osteoarthritis Bone arises from cartilage: Cartilage BoneBoth

A Sliver Lining

Chondroblasts and ‘Clasts

Chondrocytes are Family Practitioners

Dynamic Support System

Feedback system Architectonic reflects lines of stress Buildup of bone reduces deformation Osteoporosis should increase response

Competitive Physiology “Static loading does not prevent osteoporosis” Rubin, CT, Lanyon, LE, Baust, G: “Modulation of bone loss during calcium insufficiency by controlled dynamc load.” Calcif Tis Int 1986;38:

Turkey wings lead the way Competitive Physiology “Static loading does not prevent osteoporosis” “Short periods of dynamic loading protect the bones in calcium-deficiency.” Rubin, CT, Lanyon, LE, Baust, G: “Modulation of bone loss during calcium insufficiency by controlled dynamc load.” Calcif Tis Int 1986;38:

Turkey wings lead the way 3H uridine rises six-fold after loading 1 8 seconds of loading = prevention 2 72 seconds of loading > 30% - 40% 2 Nothing more with 720 or 3600 seconds 2 1. Pead, MJ, Suswillo, R, Skerry, TM et al: “Increased 3H uridine levels in osteocytes following a single short period of dynamic bone loading in vivo.” Calcif Tisue Int 1988;43: Rubin, CT, Lanyon, LE: “Regulation of bone formation by applied dynamic loads. J Bone Joint Surg 1984;66A:

Turkey wings lead the way Eccentric pulls on periostium increase bone strength, reversing osteoporosis Lanyon, L.E. “Osteoporosis and exercise.” Topics in Geriatric Rehabilitation. March :(2)pp

Woolf, J: The Law of Bone Transformation. Berlin, A. Hirschwald, Deforming force