A Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Paracelsus Paracelsus was so grandiose And perhaps just a little bit gross Manure, blood, and sand and thus you create man But what makes it a poison is dose! The Undecided Dose Too much of a thing makes you blue But not having it can kill you too Too much or too little Let's not be so fickle We'll go Dutch and divide it by two. Limericks by Toni Hayes

A Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

A Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology A Small & Large Dose of Toxicology Welcome !! Introduction to the Health Effects of Chemicals Steven G. Gilbert, PhD, DABT

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Objective Increase our understanding of how chemicals affect human health.

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Course evaluation – Very important Other stuff!!! Ask questions – Talk to me!!! Logistics

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Special Thank you to: Northwest Environmental Training Center Thanks to Organizers

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology 8:00 am Registration 8:30Welcome to “A Small Dose of Toxicology”S. Gilbert 8:40An Introduction to Principles of ToxicologyS. Gilbert 10:00Break 10:30Non-Cancer and NeurotoxicologyS. Gilbert 11:30Q&A Basic toxicS. Gilbert 12:00 pmLunch – 1:00Case Study: Health Effects of LeadS. Gilbert 2:00An Introduction to Repro & Devel ToxicologyS. Gilbert 2:45Break 3:00Precautionary Assessment – Beyond RA S. Gilbert 4:00Questions and Answersall 4:30Adjourn A Small Dose of Toxicology

Welcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology 8:00 amRegistration 8:30WelcomeS. Gilbert 8:40Toxicology and Drug DevelopmentR. Ponce 9:30Managing Exposure – Occupational Issues.J. Camp 10:15Break 10:45NanotoxicoloogyW. Smith 11:45Question and AnswersAll 12:00 pmLunch – 1:00Respiratory ToxicologyM. Morgan 2:00Pollution in People – BiomonitoringS. Gilbert 2:30Break 2:45Melamine Risk AssessmentS. Wong 3:45Ethical, Legal, Social Issues – e-wasteS. Gilbert 4:15Questions and AnswersAll 4:30Adjourn A Large Dose of Toxicology

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology A Small Dose of Toxicology See: -- smdosesmdose

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Small Dose of Toxicology

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Milestones of Toxicology

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology A free toxicology encyclopedia and resource center that anyone can edit. Toxipedia provides comprehensive, accurate, and scientifically based information on the hazards and risks of chemical and physical agents, with the goal of advancing human and environmental health. ToxipediaToxipedia

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology The World Library of Toxicology

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Toxipedia suite of sites

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Connecting Gardeners and Experts for Green Gardening Solutions  Identify Your Pest  Find the Right Plant  Ask the Experts  Garden Design Guide  Indoor Pest Control Supported by Local Hazardous Waste Management Program in King County, WA.

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology 17

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Healthy World Theater promote awareness and understanding through the arts to create a more healthy and peaceful world plays, poems, jokes, fiction, music, cartoons, haiku, and even limericks

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology 19

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Washington Nuclear Museum and Educational Center (WANMEC) learning from the past for a safer tomorrow a project of Washington Physicians for Social Responsibility - funded in part by WA DOE

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Healthy World Press ( publishes interdisciplinary books connecting science, history, and art. Healthy World Press Particles on the Wall Particles on the Wall: An interdisciplinary exhibit connecting science and art in exploring the history of Hanford and major themes of today's nuclear age

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Toxipedia Connecting Science and People Washington Nuclear Museum and Education Center - Integrate Pest Management World Library of Toxicology Healthy World Theater A product of the Institute of Neurotoxicology and Neurological Disorders (INND) For more information contact Steven G. Gilbert at Connecting Gardeners and Experts for Green Gardening Solutions Learning from the past for a safer tomorrow Uniting art and science for a healthy, peaceful world Connecting Scientists and Experts to Improve Global Health

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology LDDI Consensus Statement Scientific Consensus Statement on Environmental Agents Associated with Neurodevelopmental Disorders Developed by the Collaborative on Health and the Environment’s Learning and Developmental Disabilities Initiative November 7,

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology LDDI Consensus Statement Given the established knowledge, protecting children from neurotoxic environmental exposures from the earliest stages of fetal development clearly is an essential public health measure if we are to help prevent learning and developmental disorders and create an environment in which children can reach and maintain their full potential.

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology NW Public Health See: nwph Public Health and the Precautionary Principle By Steven G. Gilbert

A Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Precautionary Principle “When an activity raises threats of harm to human health or the environment, precautionary measures should be take even if some cause and effect relationships are not fully established scientifically.” Wingspread Conference, 1998.

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology Child Health

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology So Many Chemicals so Little Data 2863 above 1 Million pounds 78.2% no data 21.4% some data 12 or 0.4% good data

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology  Nearly 12 million children (17%) under age 18 in the US suffer from one or more developmental disabilities  Learning disabilities – 5-10% of kids in public school  ADHD – 3-6% of all school kids, maybe higher The Consequences

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology A Small Dose of – web site A Small Dose of Toxicology

A Small Dose of ToxicologyWelcome to Small Dose of ToxicologyWelcome to Small & Large Dose of Toxicology A Small Dose of Toxicology