Monday, March 5, 2012  Put your Extra Credit in bin on front desk  Multiple Choice (13/18 or less) AND Short Answer Retakes Must be done in tutorial today and tomorrow  No homework

Protein Structure Checkup Version A: #10 Version B: #5 Choose answer A or B for that question.

Make an entry- Entry 16- Protein Networks-3/5/12

Metabolic Networks Introduction

Network Review Network an interconnected or interrelated chain, group, or system. Nodes members of the network Edges the relationships between the nodes

Food Network

Lactase Lab Lactose is composed of Galactose and Glucose Lactase breaks lactose into…

Lactose Lactase How can we represent this with nodes and edges?

Lactose Glucose Lactase Galactose

Metabolic Network

Glycogen UDP-Glucose Lactase Galactose Galactose P UDP-Galactose Glucose-1-P Glucose-6-P Glucose ATP ADP

Key Terms Metabolism: all the chemical reactions occurring within a cell or a whole organism Metabolite: any molecule produced by chemical reactions of metabolism

A metabolic pathway is a series of enzyme reactions connecting one metabolite to another –Like a single food chain within a food web Click here for animation of metabolic pathway

Metabolic Network ABCD E F

ABCD E F X

C B A X E F D Result: -Accumulation of B -Decrease of C, D, E, and F

“Coat Color in Labrador Retrievers” CocoaMidnight

Guiding Question: “How does variation exist between organisms?” Read: “Coat Colors in Labrador Retrievers” to help you answer this question.

Vocab to know for reading. Pigment = A substance, such as chlorophyll or melanin, that produces a characteristic color in plant or animal tissue. Skin and Hair pigments are produced in cells called melanocytes. Synthesize = to put together.

Labrador (dog) pigmentation Tyrosine Dopaquinone Brown pigment Black pigment Yellow pigment tyrosinase TRP-2 TRP-1 What color is the dog’s coat? Black

Tyrosine Dopaquinone Brown pigment Black pigment Yellow pigment tyrosinase TRP-2 TRP-1 What would happen if the enzyme TRP – 1 was missing? Black pigment What color is the dog’s coat?Brown

Tyrosine Dopaquinone Brown pigment Black pigment Yellow pigment tyrosinase TRP-2 TRP-1 So what would happen if the enzymes TRP – 1 and TRP-2 were both missing? Black pigment What color is the dog’s coat?Yellow Brown pigment