Things to Do Today Observe Urinalysis Plates –Note hemolysis & Count Colonies on BAP –Observe EMB plate Blood Lecture Blood Typing Differential WBC Count Observe Parasitic Blood Slides
Whole Blood Plasma Buffy coat Hematocrit
RBCs
RBC Disorders Anemias -hemolytic -Iron deficiency -aplastic -sickle cell Polycythemia
Wikipedia Commons, used with permission WBCs
monocyte lymphocyte neutrophileosinophilbasophil Wiley
WBCs WebPath, used with permission
WBCs lymphocytemonocyte Medicine USC, used with permission Vs.
Leukocyte Disorders Leukemia Infectious mononucleosis Leukopenia
Formation of platelets
Clotting
Blood Types
Hemolytic DZ of the Newborn Mom must be Rh (-) Father must be Rh (+) A child must be Rh (+) A subsequent child must be Rh (+)
Hemolytic DZ of the Newborn
Blood typing
Watch demo of Blood Smear 10 sec in dye sec in rinse
Blood Parasites Trypanosoma cruzi Chaga’s disease Leishmania Leishmaniasis Plasmodium vivax Malaria Trypanosoma gambiense Sleeping sickness Microbe Disease
Trypanosoma cruzi Etiological Agent for Chaga’s disease KM 1000x
Rhodnius: Vector for Chaga’s disease AKA assassin bug; kissing bug KM
Blood Parasites Trypanosoma cruzi Chaga’s disease Leishmania Leishmaniasis Plasmodium vivax Malaria Trypanosoma gambiense Sleeping sickness Microbe Disease
Leishmania Life Cycle
Leishmania Vector: sandfly KM 1000x
A Patient Suffering from leishmaniasis
leishmaniasis DermAtlas, used with permission
leishmaniasis DermAtlas, used with permission
leishmaniasis DermAtlas, used with permission
leishmaniasis Dermis.net, used with permission
leishmaniasis Dermatology Image Atlas, used with permission
Blood Parasites Trypanosoma cruzi Chaga’s disease Leishmania Leishmaniasis Plasmodium vivax Malaria Trypanosoma gambiense Sleeping sickness Microbe Disease
Malaria Causative agent: Protozoan Plasmodium One of the most severe of all parasitic diseases Endemic is most tropical areas Plasmodium are amoeboid, intracellular protozoa that infect erythrocytes and other tissues Transmitted by the female Anopheles mosquito
The Worldwide Incidence of Malaria
The life cycle of the malaria parasite Plasmodium
The “ring” stage of the malarial parasite Plasmodium falciparum Seen as dark, circular structures within red blood cells Malaria in RBCs
Plasmodium vivax Malaria KM 1000x
Blood Parasites Trypanosoma cruzi Chaga’s disease Leishmania Leishmaniasis Plasmodium vivax Malaria Trypanosoma gambiense Sleeping sickness Microbe Disease
Trypanosoma gambiense Sleeping Sickness Vector: Tsetse fly KM 1000x
Blood Types Type OType AB Type AType B Anti A antibody Anti B antibody