School of Population Health University of Melbourne Global systematic review initiatives: moving forward in partnership Elizabeth Waters

The following slides were presented at a meeting of potential editors and methods advisors for the proposed Cochrane review group in February The slides were designed to promote discussion rather than represent the views and directions of this group.

IUHPE Global Program 1. The global focus that IUHPE offers in terms of having IUHPE members active in the reviews from around the world 2.The relationship of the capacity building vision of IUHPE to the work of Cochrane 3.The opportunity to explore in greater detail arising methodological questions, in particular issues around the strengths and weaknesses of the many different approaches that we take with regard to evidence 4.The opportunity to examine the evidence base for health public policy – building on the discussions arising from the recent (Feb 2008) meeting of experts in London on this topic 5.The possibilities to explore more the evidence base related to KSTE, particularly to examine the rather meager literature on the evidence of effective approaches to translation 6.The inclusion of a chapter in the next monograph, authored jointly, that addresses the mutual workings and understandings of Cochrane, GPHPE and other approaches to building evidence in health promotion 7.The emphasis on the role of social determinants and how that epidemiologically based knowledge (particularly arising from the CSDOH) is transformed into effective health promotion interventions 8.Cochrane – GPHPE presentations in the 2010 IUHPE Conference in Geneva.

Centre for Public Health Excellence Work programme Mike Kelly and Antony Morgan

What is NICE? The National Institute for Health and Clinical Excellence (NICE) is the independent organisation responsible for providing national guidance on the promotion of good health and the prevention and treatment of ill health.

Work Programme Guidance published and in development (slides 4-6) Revising the methods and process manuals (slides 7-9)

Interventions guidance published Promoting physical activity in primary care (March 06) Smoking cessation in primary care (March 06) Preventing teen conceptions and STIs (Feb 07) Substance misuse and vulnerable young people (March 07) Supporting the smoking ban (April 07) Alcohol and Schools (Nov 2007)

Interventions guidance under development Social and emotional well being in primary school children (March 08) Mental health and older people (April 08) Physical activity in the workplace (May 08) Reducing mortality in highly disadvantaged communities (June 08) Preventing the uptake of smoking in children (July 08) Mental health and the workplace (Nov 08) Needle exchange schemes (Feb 09) Improving the uptake of immunisation (April 09) Secondary schools and mental well being (July 09)

Programme guidance (published in red) Obesity (Dec 06) Behaviour change (Oct 07) Physical activity and the environment (Jan 08) Smoking cessation services (Feb 08) Community engagement (Feb 08) Maternal and child nutrition (March 08) Physical activity, play and sport in pre school and school aged children (Jan 09) Long term sickness incapacity (Feb 09) Health literacy in schools with reference to sex education – PSHE (Sept 09) Alcohol (March 2010)

Revising the process and methods manuals Project statement : to update the CPHE methods and process manuals and appendices by June 2008 for stakeholder consultation in October-December 2008 and completion in March 2009 (publication April 2009)

Areas currently under development (1) Scope Preparation –Standardising key questions (on effectiveness, cost effectiveness, equity, external validity, implementability) Searching the evidence base –forensic searching, snowballing, searching for grey literature, indexing) Assessing the strength of evidence –Assessing quality, internal and external validity, reviewing fitness for purpose of checklists, applicability, impact on health inequalities Health Economics –Reviewing methods of health economic analyses, discounting, qalys beyond health outcomes, decision analysis frameworks

Areas currently under development (2) Data presentation and synthesis –Use of forest plots, standardising evidence statements, synthesising qualitative literature, producing narrative summaries Creating recommendations –Developing an explicit sequential algorithm for deriving recommendations Fieldwork methodology –Reviewing methodology for testing the implementability of guidance with stakeholders Stakeholder consultation –Dealing with lay evidence and evidence submitted by stakeholders

CDC Community Guide Greater alignment Perhaps shared reviews – or common protocols and searches, with deviation around study origin and context Joint publication on review delineation Sharing of protocols and prospective work program via ‘extranet’ CDC staff working on Cochrane reviews

WHO Global Commission on Social determinants of health – evidence and equity