By Michael Riel

 Joints: Physical Connection between 2 or more bones to cause mobility. Example: the jaw and the mandible, phalanges to metacarpals etc.  Cause mobility  TMJ- pain, inflammation and stiffness in the joint between the mandible and jaw bone (Temporary-Permanent).  How? With the presence of Metalloproteinase, which are labeled MMP-7 and MMP-9 for short (Loredo).

 Condylotomy surgical procedure where the condyle of the bone is separated from the joint for “remodeling”the bone structure.  70%-90% success on TMJ mobility (Puricelli)  What about arthritis? To be more specific, osteoarthritis (location: hinje joint for the hand)?

 4 groups: Control, TMJ, Control, Arthritis  Voluntary Patients with a medical history of TMJ or arthritis (confidential).  Medical examinations are required for the experiments.  Begin experiment with Anesthesia($100,000/L)  Proceed with condylotomy and the use of adrenocortical steroids ($150,000/lb).

Use surgical condylotomy procedure on 4 groups:  Incision in the mouth for TMJ and control TMJ.  Incision on the skin for arthritis and control.  Separate the bone from the joint.  Use Steroid to be placed around the joint for repression and relaxant to cause less inflammation and provide restructure of the joint.  Rehabilitation  Observe and record 4 times a day (6 hours) for 8-12 weeks.

Success:  No pain for all groups.  Growth and restructure of tissues in the cartilage.  Same mobility in control groups.  More mobility in TMJ and arthritis. Failure:  Stiffness starts developing in the joint in control groups.  Same symptoms arises from arthritis and TMJ.

 If we are able to create more mobility for patients with TMJ and osteoarthritis, we can use this factor as a start of reversing and relieve the symptoms of arthritis.  More resources and data for future experiments.

  eng.htm  ive%20Most%20Common%20Forms%20of%20Arthritis.pdf  Puricelli Edella, Adriana Corsetti, Julieta Tavares, Giuliano Luchi. "Clinical-surgical treatment of temporomandibular joint disorder in a psoriatic arthritis patient." (2013) 9:11; 1-7.  Loredo, Cortez, Ramon Leonardi, Geo Musumeci,, and. "An ex vivo study on immunohistochemical localization of MMP-7 and MMP-9 in temporomandibular joint discs with internal derangement." (2013): 57:e Print.