Click to edit Master title style Click to edit Master subtitle style ©2008 Howard Hughes Medical Institute Click to edit Master title style Click to edit Master subtitle style HHMI MEDICAL RESEARCH FELLOWS PROGRAMS FOR MEDICAL, DENTAL, AND VETERINARY STUDENTS ©2011 Howard Hughes Medical Institute

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS HHMI IS: A philanthropy established by the aviator and entrepreneur Howard Hughes Serves society through support of biomedical research and science education Largest U.S. philanthropy dedicated solely to biomedical research and education

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS ~400 Investigators 148 Members of the National Academy of Sciences! 15 Nobel laureates! HHMI INVESTIGATORS

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS ELIGIBILITY In good standing at a medical, dental, or veterinary school located in the U.S. Not currently in a combined professional degree/Ph.D. program May not have a Ph.D. in a laboratory-based biomedical science Do not have to be from a research-oriented school Prior research experience is advantageous (Janelia Farm option in the Med Fellows Program requires prior research experience) U.S. citizenship not required but you must be eligible to work in the U.S.

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS Work at any academic or nonprofit research institution in the U.S., except the NIH Research may be conducted abroad if mentor is affiliated with a U.S. institution Spend a year doing research without being displaced from your local surroundings RESEARCH LOCATION

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS Medical Fellow Phil Pauerstein (right) with his mentor, HHMI investigator Dr. Seung Kim at Stanford University School of Medicine Your research may be a basic, translational or applied biomedical project. Mentor and project established before you apply Selection of mentor and research project are key components of the application process Mentor may be an HHMI investigator or any other biomedical investigator RESEARCH PROJECT AND MENTOR

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS SELECTING A MENTOR Seek advice from faculty and administration. Talk with several possible mentors. Confirm that the mentor has a solid training and publication record, sustained external grant support, and the time, interest and experience to train you. Talk with other trainees who have been in the lab you are considering. Medical Fellow Katie Cook and her mentor, HHMI investigator Elaine Fuchs at Rockefeller University

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS JOINT INITIATIVES Four joint initiatives for the Med Fellows Program: 1. Foundation Fighting Blindness supporting up to 4 fellows doing research in inherited retinal degenerative diseases. 2. GM Trust supporting up to 1 fellow studying Duchenne Muscular Dystrophy. 3. Society of Interventional Radiology Foundation funding up to 1 fellow doing preclinical interventional radiology research. 4. Burroughs Wellcome Fund (BWF) for support of up to 2 veterinary students.

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS MEDICAL FELLOWS AT JANELIA FARM Live and work at HHMI’s Janelia Farm Research Campus in Ashburn, VA (near Washington, D.C.) Use innovative and emerging technologies to research neuronal network function or imaging at the cellular and molecular level. Two-step application process requiring: Prescreening application due by November 1

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS INFORMATION RESOURCES View projects of last year’s class in 2011 Medical Fellows Meeting Book Search for HHMI investigators interested in mentoring Med Fellows Go to:

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS Travel to the Washington D.C. area twice during the fellowship year to network and share scientific research Travel to professional meetings, HHMI science meetings and Med Fellows regional group meetings PROFESSIONAL TRAVEL

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS Panel discussions, informal science meetings and networking opportunities with other Med Fellows Symposia and lecture series featuring HHMI investigators and other prominent physician- scientists Mentoring by HHMI Physician- Scientist Early Career Awardees Advice from HHMI Med Fellows alumni REGIONAL GROUPS

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS Annual stipend of $28,000 $5,500 fellow’s allowance for medical, dental, and vision insurance, and education-related expenses $5,500 research allowance for travel to scientific meetings, Med Fellows regional meetings, and some research-related expenses FINANCIAL SUPPORT

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS LOAN DEFERMENT Some schools have special status to remain enrolled; fees vary per school Check with registrar and financial aid office HHMI can help complete deferment or forbearance forms (request from your loan servicing center)

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS 2008: 228 applicants from 73 schools 68 accepted from 27 schools 2009: 231 applicants from 65 schools 70 accepted from 28 schools 2010: 274 applicants from 74 schools 74 accepted from 27 schools 2011: 244 applicants from 81 schools 72 accepted from 30 schools PROGRAM STATISTICS ( )

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS Deadline: January 11 Must select mentor and write a research plan as part of the application process No interview (except for selected Janelia Farm applicants) External review panel of scientists Apply online: APPLICATION INFORMATION

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS SUMMER MEDICAL FELLOWS PROGRAM New opportunity to spend a summer conducting research in the laboratory of an HHMI investigator or Janelia Farm researcher 8-10 weeks of summer research with a stipend of $500 per week plus up to $1,000 for roundtrip travel to fellowship site Opportunity to experience outstanding biomedical research and decide whether to apply for the year-long Medical Research Fellowship Develop your knowledge, skills and research experience 20 summer fellowships available Application opens: November 1; deadline: February 15

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS ALUMNI NETWORK Composed of all current and former HHMI Medical and Graduate Program participants Networking, gain collaborations and valuable resources for career development Alumni-organized events throughout the country (e.g., seminars, workshops, socials) ¯ San Francisco Bay ¯ Boston ¯ Chicago ¯ Cleveland ¯ Washington D.C./Baltimore ¯ Michigan ¯ New York ¯ Research Triangle ¯ Seattle ¯ Southern California ¯ Texas

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS Alfredo Quiñones-Hinojosa, M.D. HHMI Medical Fellow, Associate Professor of Neurosurgery, Oncology, Neuroscience, and Cellular and Molecular Medicine Johns Hopkins University School of Medicine HHMI Physician-Scientist Early Career Awardee, 2006 “Since first applying for an HHMI physician-scientist fellowship more than ten years ago, I've believed that the hybrid position offers unique and rewarding opportunities. As clinicians, we are able to provide compassionate care for patients. As scientists, we can investigate the pathological basis of disease and discover new treatments for devastating illnesses. The patients in my clinical program motivate me to research the mechanisms of brain-tumor development, and my laboratory research addresses basic questions about the human brain and brain tumors...With the support of the NIH and the HHMI, I hope to have the opportunities and resources to investigate and develop new ways to fight this disease.” ALUMNI PERSPECTIVES

Click to edit Master title style Click to edit Master subtitle style ©2011 Howard Hughes Medical Institute HHMI MEDICAL EDUCATION PROGRAMS Kimberly Stegmaier, M.D. HHMI Medical Fellow, 1994 Assistant Professor, Department of Pediatrics, Harvard Medical School and Principal Investigator, Pediatric Oncology, Dana-Farber Cancer Institute HHMI Physician-Scientist Early Career Awardee, 2006 “The HHMI medical student research fellowship was a deciding experience in my path to a laboratory-based physician-scientist career. It was truly a life-altering year. I am now an independent investigator with a research program focused on integrating chemical genomic, genetic, and proteomic approaches to discover new protein targets and lead compounds for cancer therapy.” ALUMNI PERSPECTIVES