Applied Aspects (Clinical Consideration) Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology.

Slides:



Advertisements
Similar presentations
MUSCULAR SYSTEM Karen Lancour Patty Palmietto
Advertisements

SMOOTH MUSCLES Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine Almaarefa.
Molecular Basis of Skeletal Muscle Contraction Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology.
MİYOPATİLER Prof.Dr.Aytekin Akyüz CÜ Tıp Fak Nöroloji AD.
Adaptations to Resistance Training. Resistance Training: Introduction Resistance training yields substantial strength gains via neuromuscular changes.
The Muscular System Functions, Anatomy, Physiology, Care, Injuries & Illnesses of our Muscles, Ligaments & Tendons.
Duchenne Muscular Dystrophy
A Few Muscular Disorders 2 Much of the text material is from, “Principles of Anatomy and Physiology, 14th edition” by Gerald J.
By: Alisha Kunz, Julia Rodenberg, Tyler Traisman and Nathan Wegner Goanimate.
NEUROMUSCULAR JUNCTION
Neuromuscular Adaptations to Resistance Training An Exercise Prescription for Athletic Performance.
CHAPTER 8 PRINCIPLES OF STRENGTH TRAINING ASSESSMENT AND PRESCRIPTION.
By: Isabelle Masloski and Will Michels Period 4.  Muscular Dystrophy is an inherited disorder where your muscles weaken and tissue is loss.  It continually.
Human Genetic disorders
SMOOTH MUSCLES Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine Almaarefa.
Control of Motor Movement Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine.
Skeletal Muscle Mechanics
Skeletal Muscle Mechanics Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine.
STRUCTURE OF SKELETAL MUSCLE Dr.Mohammed Sharique Ahmed Quadri Assistant Professor, Physiology.
Applied Aspects (Clinical Consideration) Dr. Abdelrahman Mustafa Department of Basic Medical Sciences Division of Physiology Faculty of Medicine Almaarefa.
How does the functions of the muscles effect Muscular Dystrophy?? And what could be done to increase muscle function?? MY QUESTION(S):
Duchenne Muscular Dystrophy
1 Chapter 11 Muscular System. 2 Outline Types and Functions of Muscles – Smooth – Cardiac – Skeletal Muscle Innervation Whole Muscle Contraction – Oxygen.
PANCREATIC HORMONES-II Dr.Mohammed Sharique Ahmed Quadri Assistant professor Almaarefa College 1.
The Muscular System.
Muscular System. The Muscular System Muscles are responsible for all types of body movement Three basic muscle types are found in the body Skeletal muscle.
Copyright © 2010 Pearson Education, Inc. Muscle Fiber Type Classified according to two characteristics: 1.Speed of contraction: slow fibers or fast fibers.
(DMD) Duchenne Muscular Dystrophy. History of DMD It was first described by a french neurologist named Guillaume Benjamin Amand Duchenne in Previous.
LOU GEHRIG’S DISEASE.  Also known as Amyotrophic Lateral Sclerosis  Is a disease of the nerve cells in the brain and spinal cord that control voluntary.
OF THE MUSCULAR SYSTEM Diseases and Disorders. Anabolic Steroids Anabolic steroids are man-made substances related to male sex hormones. Medical uses.
Force of Muscle Contraction
Applied Aspects (Clinical Consideration) Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology.
Molecular Basis of Skeletal Muscle Contraction
CARDIAC MUSCLE Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine Almaarefa.
Quiz Ch.9 Part III 1.What is fatigue? 2.What is most likely the cause of muscle fatigue? 3.What are the two main types of contractions? (one describes.
Pgs Muscular Dystrophy Weakening/breakdown of the voluntary muscle cells A group of over 30 types of inherited muscular diseases Duchenne’s.
Skeletal Muscle Mechanics Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine.
INTERCELLULAR COMMUNICATION
Muscle diseases and disorders
Skeletal Muscle Mechanics Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine.
Comparison of different types of muscles Dr. Shaikh Mujeeb Ahmed Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of.
DISEASE ASSOCIATED WITH MUSCLES IN CHILDHOOD MUSCULAR DYSTROPHY.
Motor Unit & It ’ s Excitation By: Baljit Brar. What Is a Motor Unit? A Motor Unit is described as being a motor neuron plus the muscle fibres that it.
Completion of Skeletal Muscle and comparison to Smooth Muscle.
About Contractions, muscle disorders, and the effects of exercise.
Date:01 December 2015 Time:6:30 – 9:30 pm Location:Emory University Presentation Room 308 Speakers:Dr. John Richardson National DMD Assoc. President Got.
Muscular System Sports Training and Physiology Kociuba
1.05 Understand the functions and disorders of the muscular system.
Muscular Adaptations to Exercise Chapter 14. Meetings 2 nd year Health & PE 3 rd years who will be out on prac mid session quiz followup.
Skeletal Muscle Metabolism and Fiber Types Dr.Mohammed Sharique Ahmed Quadri Assistant Professor, Physiology.
Developmental Aspects of Muscular System. Development Embryo Muscular system laid down in segments Each segment is invaded by nerves First movements of.
Lesson 11.1: Muscle Fitness Basics Question What is meant by the term muscular endurance?
Diseases and Disorders
Fibromyalgia Chronic, widespread pain in specific muscle sites. Symptoms: Muscle stiffness Numbness or tingling in the arms or legs Fatigue Sleep disturbances.
Duchenne's Muscular Dystrophy By: Timothy Taggart & Mark Miville-Deschenes.
Muscle Strength, Power, and Endurance
Muscular System Diseases and Disorders. Diseases and Abnormal Conditions Fibromyalgia- widespread pain in muscle sites Stiffness, aches, numbness, tingling.
Ligament- A short band of tough,
Molecular Basis of Skeletal Muscle Contraction
A Few Skeletal Muscle Disorders
Pathology of the Muscular System.
Dr.Mohammed Sharique Ahmed Quadri
Dr.Mohammed Sharique Ahmed Quadri
1.05 Understand the functions and disorders of the muscular system
Dr.Mohammed Sharique Ahmed Quadri
INTERCELLULAR COMMUNICATION
Developmental Aspects of the Muscular System
A Few Skeletal Muscle Disorders
Presentation transcript:

Applied Aspects (Clinical Consideration) Dr.Mohammed Sharique Ahmed Quadri Assistant Professor Department Basic Medical Sciences Division of Physiology Faculty of Medicine Almaarefa Colleges

Disease of motor neurons Poliomyelitis: cell bodies of motor neurons are destroyed by polio virus

Disease of motor neurons (continues) Amyotrophic lateral sclerosis: Degeneration and eventual death of motor neurons Loss of motor control Progressive paralysis leading to death exact cause is uncertain

Chemical agents & diseases that affect Neuromuscular Junction

Myasthenia Gravis

Muscle Hypertrophy Size of muscles can be increase by regular bouts of anaerobic, short duration, high intensity, resistance training, such as weight lifting -Increase in diameter of fast glycolytic fibers - increased synthesis of actin and myosin filaments -Stress triggers signaling proteins that turn on genes that direct the synthesis contractile proteins

Muscle Injury

Strain Injuries to Muscle Injury can occur to a muscle that is overstretched while unstimulated, But most injuries occur during eccentric contraction,. Relatively few injuries occur under isometric or isotonic (concentric) contraction conditions. The site of injury is most often at the myotendinous junction

Strain Injuries to Muscle In some cases, there is complete disruption of the muscle (avulsion), although usually separation is not complete. Symptoms: – Soreness – Weakness, – Delayed Swelling, And – “Bunching up” in extreme cases Delayed-onset muscle soreness, as often experienced after unaccustomed exercise, also results from strain injury, but on a smaller scale.

MRI PICTURES OF MUSCLE INJURIES

Strain Injuries to Muscle

Influence of Testosterone Muscle fibers in males are thicker, larger and stronger than females, because of action of steroid hormone testosterone. Testosterone promotes the synthesis of actin & myosin filaments Use of Anabolic androgenic steroids by athletes – Really winners or losers ?

Muscle Atrophy If muscle is not used its actin & myosin content decreases. – Disuse atrophy : Plaster cast Prolonged bed confinement Space( loss of gravity ) – Denervation atrophy:

Muscular Dystrophy A fatal Hereditary pathological conditions characterized by progressive degeneration of contractile elements. Affects young boys leading to death before age of 20. There are many different types of muscular dystrophy. They include: Becker muscular dystrophy Duchenne muscular dystrophy Emery-Dreifuss muscular dystrophy Limb-girdle muscular dystrophy

Muscular Dystrophy X-linked recessive disorder Defective gene responsible for Duchene muscular dystrophy- gene normally produces dystrophine Treatment under research – Gene Therapy – Cell Transplantation Approach – Utrophin Approach – Anti-Myostatin Approach

References Human physiology by Lauralee Sherwood, 7 th edition Text book physiology by Guyton &Hall,12 th edition Text book of physiology by Linda.s contanzo,third edition 18