RNA nanotechnology for computer design and in vivo computation by Meikang Qiu, Emil Khisamutdinov, Zhengyi Zhao, Cheryl Pan, Jeong-Woo Choi, Neocles B.

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Presentation transcript:

RNA nanotechnology for computer design and in vivo computation by Meikang Qiu, Emil Khisamutdinov, Zhengyi Zhao, Cheryl Pan, Jeong-Woo Choi, Neocles B. Leontis, and Peixuan Guo Philosophical Transactions A Volume 371(2000): October 13, 2013 ©2013 by The Royal Society

Comparison of the electronic computer and a molecular-scale computer. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

Logic-gate systems with Ag+ and Hg2+ ions as inputs and electrochemical signals as output detected by differential pulse voltammetry (DPV). Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

Historical outline of RNA nanotechnology. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

Significance and uniqueness of RNA nanotechnology. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

Fabrication of RNA nanoparticles. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

Workflow diagram of functional RNA construction based on the pRNA molecule. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

Illustration of toolkits to obtain RNA nanoparticles. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

Application RNA nanotechnology for computer design. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

AFM images of pRNA nanoparticles obtained by ‘hand-in-hand’ interaction following toolkit no. 1 [87]. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

AFM images of pRNA nanoparticles obtained by ‘foot-to-foot’ interaction following toolkit no. 2 [87]. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

AFM images of pRNA nanoparticles obtained by ‘foot-to-foot’ interaction following toolkit no. 3 [87]. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society

The development path of molecular-scale computing. Meikang Qiu et al. Phil. Trans. R. Soc. A 2013;371: ©2013 by The Royal Society