Dante Luiz Escuissato. Infections are related to specific immunity defects. Phagocyte abnormalities and intravenous catheters: Aspergillus and Candida.

Slides:

Advertisements

Similar presentations

I(x) Active TB Routine; FBE WCC (Infection) Hb (Anaemic of chronic disease) U&Es (baseline) LFTs (baseline) ESR/CRP (inflammation/infection)

Advertisements

Can we rely on imaging and biomarkers for preemptive antifungal therapy in hematological patients? Claudio Viscoli Professor of Infectious Disease, University.

Radiologic Imaging Defines the local extent of a tumor Can be used to stage malignant disease Aids in the diagnosis Monitoring tumor changes after treatment.

Treatment of Fungal infections in Hematologic Malignancies

High-Resolution Lung CT: Key Findings and What They Mean W

Fungal infection. Endemic fungal pneumonia pathogens: – Histoplasma capsulatum – Coccidioides immitis – Blastomyces dermatitidis – Paracoccidioides brasiliensis.

OPPORTUNISTIC FUNGAL INFECTIONS

Copyright © 2006 by Mosby, Inc. Slide 1 Chapter 18 Fungal Diseases of the Lung Figure Fungal disease of the lung. Cross-sectional view of alveoli.

Respiratory Fungal Infections Dr. Ahmed Al-Barrag Asst. Professor of Medical Mycology School of Medicine and the University Hospitals King Saud University.

Radiological Category: Case Report Submitted by:Matthew Bean MSIV Faculty reviewer:Sandra Oldham M.D Date accepted: August 28, 2014 Principal Modality.

CHEST IMAGING : CH 12. Transverse CT scan obtained in a 60-year-old man with Bronchioloalveolar carcinoma: Multiple nodules surrounded by a halo.

Clinical Mycology Scott G. Filler, M.D. Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center.

Approach to Pulmonary Manifestations of HIV/AIDS

Petra Lewis MD Professor of Radiology and OBGYN Geisel School of Medicine at Dartmouth.

Christoph Lange Imaging diagnosis of tuberculosis.

Cryptococcal pneumonia and meningitis. Cryptococcus neoformans.

Thank you for viewing this presentation. We would like to remind you that this material is the property of the author. It is provided to you by the ERS.

Rare case of Cryptogenic organising pneumonia Abstract ID: 1222.

Respiratory mycoses (reduced version) Dr Elizabeth M. Johnson, Director HPA Mycology Reference Laboratory, Bristol.

How I manage pulmonary nodular lesions and nodular infiltrates in patients with hematologic malignancies or undergoing hematopoietic cell transplantation.

INTERSTITIAL LUNG DISEASE

Jed Hummel RAD 4001 CASE PRESENTATION. CT HALO SIGN Ground glass attenuation surrounding a pulmonary nodule Causes of the ground glass halo can be divided.

Respiratory Fungal Infections

Respiratory Fungal Infections

Clinical Discussant: David B. Pearse, M.D.

APPROACH TO RADIOLOGICAL DIAGNOSIS

1 Respiratory Diseases in HIV-infected Patients HAIVN Harvard Medical School AIDS Initiative in Vietnam.

Which drugs?. Mode of action of antifungals ergosterol polyenes e.g. amphotericin B polyenes azoles e.g. fluconazole azoles nucleosides e.g. 5-flucytosine.

Fungi (Chapter 28) “a group of diverse and widespread unicellular and multicellular organisms, lacking chlorophyll, usually bearing spores and often filamentous”

Staph Aureus. Staph Aureus Bronchopneumonia, Fig. 1 Poorly marginated large nodular areas of consolidation are seen in the periphery of both lungs.

1 Approach to Pulmonary Problems of Immunosuppressed Patients Dr.Özlem Özdemir Kumbasar.

K.Gohari Moghadam MD. Azar Increased survival of patients by intense immunosuppression. 2-The lung is the most frequently affected organ. 3-

Dr. A.Aziz Djamal MSc.DTM&H.SpMK(K ). 1. Cosmopolitant : Aspergillus, Candida and Cryptococcosis. 2. Exotic type : In a specific area Penicillium marneffei.

History : 24-yr-old woman with chest pain, asthenia and night sweats. She has flown back from Brasilia to France 3 weeks ago. Case of the Month 5 November.

Etienne Leroy Terquem – Pierre L’Her SPI / ISP Soutien Pneumologique International / International Support for Pulmonology Tuberculous Miliary.

RESPIRATORY FUNGAL INFECTION. YEASTMOULD FUNGIDIMORPHIC FUNGI OpportunisticPrimary Infectious Candidiasis (Candida and other yeast) Aspergillosis (Aspergillus.

Respiratory Fungal Infections

KCP 토의자 가천대 길병원 R3 정주현. Clinical History  남자 / 41 세  주소 : 발열, 인후통, 설사 ( 약 1 개월 전 ) 중국 유학 (2000 년 부터 ) 중국 광동성과 홍콩에서 사업 (2 개월 전 귀국 )  HIV, syphilis.

Spectrum of Radiologic Findings for Pulmonary Aspergillosis X. Gallardo, E. Casta ñ er, J.M. Mata, F. Novell, M. Andreu.

Systemic fungal infection (Mycosis). Candidiasis  candida albicans infection  Immune compromised Pt. 1.Skin and M.M. candidiasis 2.Ophthalmic C.  loss.

폐렴으로 오인할 수 있는 폐렴 외 질환 호흡기 내과 R3 최 문 찬.

Multifocal Consolidation with Halo Sign 경희대학교 의과대학 감염내과 박기호.

A B Case 1.Laboratory-confirmed pulmonary cryptococcosis : patient No. 32 Chest CT showed multiple cavitary nodules(A, black arrow revealed one of the.

CMV pneumonia. The patient is a 22-year-old female with congenital heart disease, common variable immunodeficiency, being treated for Burkitt' lymphoma.

Pulmonary Capillary Hemangiomatosis

Respiratory diseases caused by fungi

Reversed Halo: No Longer a Pathognomonic Sign

Fig. 1. Abnormalities on chest imaging of the patient

Respiratory Fungal Infections

Figure 3 Response after appearance of a new lesion

(A) A 35 year old man with Wegener's granulomatosis.

Cystic and Cavitary Lung Diseases: Focal and Diffuse

Pneumocystis carinii Pneumonia

An Unexpected Cause of Diffuse Alveolar Hemorrhage in a Kidney Transplant Patient Respiration 2014;87: DOI: / Fig. 1.a Chest CT.

a-d) Typical changes over time in different diffuse lung diseases

Diagnostic contribution of positron emission tomography with [18F]fluorodeoxyglucose for invasive fungal infections A. Hot, C. Maunoury, S. Poiree, F.

Radiology assessment of pulmonary amyloidosis

Tsukamurella tyrosinosolvens and Rhizobium radiobacter sepsis presenting with septic pulmonary emboli L. Romano, T. Spanu, F. Calista, B. Zappacosta,

Recurrent Fevers, Cough, and Pulmonary Opacities in a Middle-Aged Man

Role of early diagnosis and aggressive surgery in the management of invasive pulmonary aspergillosis in neutropenic patients D. Caillot, L. Mannone,

Radiodiagnostic imaging

Lecturer name: Dr. Ahmed M. Albarrag

Lecturer name: Dr. Ahmed M. Albarrag

2016 합동집담회 증례 발표 서울대학교병원 영상의학과 유진영.

A) Chest radiograph at admission showing multiple bilateral nodular images, which are more abundant in the right lung. b) Chest computed tomography scan.

Fig. 1. A 31-year-old woman with pulmonary granulomatosis with polyangiitis mimicking septic pneumonia resulting from middle ear infection. A. Chest radiograph.

Different stages of invasive pulmonary aspergillosis (IPA) and the potential therapeutic importance of different tissue subcompartments. Different stages.

A and B, Computed tomography (CT) of the chest prior to cabozantinib therapy demonstrated a dominant mass in the left upper lobe (B, black arrow), measuring.

Lesions that represent potential mimickers of cyst-related primary lung malignancies. a) Irregular thick-walled cystic airspace in a 74-year-old male as.

Presentation transcript:

Dante Luiz Escuissato

Infections are related to specific immunity defects. Phagocyte abnormalities and intravenous catheters: Aspergillus and Candida species. T cell abnormalities and corticosteroid therapy: Cryptococcus neoformans, Histoplasma capsulatum, Coccidioides immitis, Pneumocystis jiroveci, and Candida species.

Am J Roentgenol 2005;185:

Fusarium sp Aspergillus sp

Pseudomonas sp.

Infections Fungal infections (invasive aspergillosis, candidiasis, zygomycosis, fusariosis) Viral and bacterial infections Neoplasia Bronchoalveolar carcinoma Kaposi sarcoma Angiosarcoma metastasis Vasculitis (Wegener granulomatosis) Br J Radiol 2005;78:

Chest X-ray: isolate or multiple nodular opacities, cavitate lesions, alveolar opacities. CT: nodules and alveolar opacities, with or without the halo sign. Radiographics 2001;21: Braz J Infect Dis 2007;11:

Halo sign: 33-60%, disappears after one week (~75%) Recommendation: CT scan performed not beyond 5 th day after symptoms onset.

CT scan: nodules, consolidations, and ground- glass opacities. Candidiais and IPA: similar CT findings in immunocompromised patients. Halo sign and cavitation not helpful to differentiate fungal infections. Am J Roentgenol 2005;185: Radiology 2005;236:

Zygomycosis: imaging abnormalites are similar to IPA in immunocompromised patients. Cryptococcosis:one or more nodules and masses (up 10cm in diameter), consolidations, and diffuse reticular a/o nodular opacities. Cavitations are seen in immunocompromised patients.

Brodoefel et al.: ~3 lesions (40 patients) Lesions enlarges inicially (~ 9 th day) stabilization regression (Am J Roentgenol 2006;187: ) Cavitation: indicative of favorable evolution.

12

18/0125/01

Chest X-ray: screening for lesions in patients with neutropenia and fever. High-resolution CT scan shows abnormalities not seen in chest X-rays. HRCT: differential diagnosis (infectious and not infectious lesions).

Nodules >10mm and lesions with the halo sign associated to clinical context are enough to presume the diagnosis of pulmonary invasive fungal infection