Chapter 17: Adaptive Immunity: Specific Defenses of the Host

Slides:



Advertisements
Similar presentations
Chapter 24 The Immune System.
Advertisements

Immune System.
The Immune System Chapter 40.
Specific Defenses of the Host: The Immune Response
The Immune System. First lines of defense: Skin Mucus Stomach acid Digestive enzymes.
 First response to particular antigen called primary response › May take a week or more to develop  Immune system remembers pathogen on subsequent.
IMMUNITY.
Humoral Immunity.
The Immune System 1.The Innate System 2.The Adaptive System.
From Blood to Host Defense Adaptive Host Defense Gregory J. Bagby, Ph.D. Office: 310 (CSRB)
Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc. Chapter 67 Review of the Immune System.
The Adaptive Immune Response
Copyright © 2010 Pearson Education, Inc. Lectures prepared by Christine L. Case Chapter 17 Adaptive Immunity: Specific Defenses of the Host.
Principles of Immunology Overview of Adaptive Immunity 1/24/06 “Too many people overvalue what they are not and undervalue what they are.” M Forbes.
General Microbiology (Micr300)
Specific Immune Defense. Antigens Antibody-generator, Non-self, Large molecules Properties: ◦1. Immunogenicity ◦2. Reactivity Antigenic determinant or.
Chapter 43: The Immune System. Lymphocytes: Specialized White Blood Cells : Two Types: B Lymphocytes T Lymphocytes.
Immunity Innate and Adaptive Immunity Cells of the Immune System
Specific Defense Mechanisms – The Immune System
Adaptive Immunity: Specific Defenses of the host
Specific Resistance = Immunity
Specific Immunity Destroy specific antigens that invade the body.
Immune System Chapter 43 ~ The Body’s Defenses. Lines of Defense Nonspecific Defense Mechanisms……
Chapter 43 ~ The Body’s Defenses. Lines of Defense Nonspecific Defense Mechanisms……
Immunogenetics chapter 22 select topics pp
Part II Biology 2122 Chapter 21
1 Adaptive, Specific Immunity and Immunization. 2 Specific Immunity – Adaptive Line of Defense The production of specific antibodies by a dual system.
17 Adaptive Immunity: Specific Defenses of the Host.
Chapter 43 ~ The Body’s Defenses
Chapter 43 Biology – Campbell • Reece
Nonspecific Defenses Species resistance – species develop diseases that are unique to it Mechanical barriers – skin and mucous membranes Chemical barriers.
Human Anatomy and Physiology Immunology: Adaptive defenses.
CHAPTER 3: Adaptive Immunity (specific body defense system)
The Immune System 2 1. Adaptive Specific immunity (acquired) = the ability of the body to defend itself against specific invading agents such as bacteria,
Immunology Innate - Adaptive Immunity Specificity Memory Tolerance.
Copyright © 2010 Pearson Education, Inc. Active Lecture Questions Chapter 17 Adaptive Immunity: Specific Defenses of the Host.
18 Animal Defense Systems Animal defense systems are based on the distinction between self and nonself. There are two general types of defense mechanisms:
Immunology Chapter 43. Innate Immunity Present and waiting for exposure to pathogens Non-specific External barriers and internal cellular and chemical.
The Adaptive Immune Response
Chapter 6 Adaptive Immunity “third line of defense”  Develops more slowly  Specific  Memory.
Copyright © 2005 Pearson Education, Inc. publishing as Benjamin Cummings The Immune System, Part II Medgar Evers College, CUNY Spring 2014, Bio 261 Prof.
___________DEFENSES of the HOST: THE IMMUNE RESPONSE
MHC Molecules Our immune system has the remarkable ability, and responsibility, of responding appropriately to a wide variety of potential pathogens in.
Immunology B cells and Antibodies – humoral
Lector Tvorko M. S.. ANTIBODIES (IMMUNOGLOBULINS) Antibodies are globulin proteins (immunoglobulins) that react specifically with the antigen that stim­ulated.
Immune system Haixu Tang School of Informatics. Human lymphoid organs.
Antigens Immunogen – a molecule that specifically interacts with an antibody or lymphocyte and elicits an immune response Antigenic determinants (epitopes)
Immunity. Body Defenses First line - barriers Skin and mucous membranes Flushing action –Antimicrobial substances Lysozyme, acids, salts, normal microbiota.
Antibody-mediated Immunity Dr. Hend Alotaibi Assistant Professor & Consultant College of Medicine, King Saud University Dermatology Department /KKUH.
Chapter 15:Adaptive Immune Response. General Characteristics Involves specialized WBC’s known as lymphocytes Response is highly specific, evolves throughout.
Ch 43 The Body’s Defense. Three lines of Defense: 1. External defenses 2. Internal (phagocytes, inflammation) 3. Specific defense: (lymphocytes) 1 & 2.
Adaptive Immunity: Specific Defenses of the Host
Humoral immunity Antibody structure Antibody diversity
Chapter Pgs Objective: I can describe how adaptive immunity (immunological memory) works. Challenging but cool, like a Rube Goldberg.
The Immune System Ch th ed Campbell’s Biology.
Specific Defenses of the Host Adaptive or Specific Immunity.
COURSE: PHARMACEUTICAL MICROBIOLOGY II COURSE CODE: 203 COURSE TEACHER: IMON RAHMAN IMMUNOLOGY.
In acquired immunity, lymphocytes provide specific defenses against infection
Chapter 43 The Immune System.
The Basics of Immunology
Chapter 17 Specific Immunity
Immune system-Acquired/Adaptive immunity
The immune system and the oral cavity
Adaptive Immunity An introduction.
CELL-MEDIATED IMMUNITY
Microbiology: A Systems Approach
The Body’s Defense Against Disease Unleashing the Fury of the Immune System Cytotoxic T-Cell killing a cancer cell Macrophage engulfing bacteria.
Resistance and the Immune System: Adaptive Immunity
Humoral Immunity.
Introduction to Microbiology
Presentation transcript:

Chapter 17: Adaptive Immunity: Specific Defenses of the Host Humoral Immunity Cellular Immunity Adaptive Immunity Antibodies Antigens $100 $100 $100 $100 $100 $200 $200 $200 $200 $200 $300 $300 $300 $300 $300 $400 $400 $400 $400 $400 $500 $500 $500 $500 $500 FINAL ROUND

Topic 1: Antibodies $100 Question How many classes of antibodies are there? 2 3 5 6 Answer = C ANSWER BACK TO GAME

Topic 1: Antibodies $100 Answer How many classes of antibodies are there? 2 3 5 6 BACK TO GAME

Topic 1: Antibodies $200 Question How many antigen-binding sites do most human antibodies have? 1 2 3 4 Answer = B ANSWER BACK TO GAME

Topic 1: Antibodies $200 Answer How many antigen-binding sites do most human antibodies have? 1 2 3 4 BACK TO GAME

Topic 1: Antibodies $300 Question A typical antibody monomer has two identical light chains and two identical heavy chains. b. two different light chains and two different c. two identical light chains and two different d. two different light chains and two identical Answer = A ANSWER BACK TO GAME

Topic 1: Antibodies $300 Answer A typical antibody monomer has two identical light chains and two identical heavy chains. two different light chains and two different two identical light chains and two different two different light chains and two identical BACK TO GAME

Topic 1: Antibodies $400 Question Generally, antibodies recognize and interact with specific regions on antigens called binding sites. haptens. epitopes. active sites. Answer = C ANSWER BACK TO GAME

Topic 1: Antibodies $400 Answer Generally, antibodies recognize and interact with specific regions on antigens called a. binding sites. b. haptens. c. epitopes. d. active sites. BACK TO GAME

Topic 1: Antibodies $500 Question The stem of the Y-shaped antibody monomer is called the ____ region. constant Fc variable active Answer = B ANSWER BACK TO GAME

Topic 1: Antibodies $500 Answer The stem of the Y-shaped antibody monomer is called the ____ region. a. constant b. Fc c. variable d. active BACK TO GAME

Topic 2: Antigens $100 Question Which receptors act as warning flags of an invading organism? B cell receptors T cell receptors Toll-like receptors CD4+ receptors Answer = C ANSWER BACK TO GAME

Topic 2: Antigens $100 Answer Which receptors act as warning flags of an invading organism? B cell receptors T cell receptors Toll-like receptors CD4+ receptors BACK TO GAME

Topic 2: Antigens $200 Question An antigenic foreign substance that has a low molecular weight is called a(n) allergen. hapten. antigenic determinant. dimer. Answer = B ANSWER BACK TO GAME

Topic 2: Antigens $200 Answer An antigenic foreign substance that has a low molecular weight is called a(n) allergen. hapten. antigenic determinant. dimer. BACK TO GAME

Topic 2: Antigens $300 Question Most antigens are composed of proteins or lipids. lipids or large polysaccharides. nucleic acids or lipids. proteins or large polysaccharides. Answer = D ANSWER BACK TO GAME

Topic 2: Antigens $300 Answer Most antigens are composed of proteins or lipids. lipids or large polysaccharides. nucleic acids or lipids. proteins or large polysaccharides. BACK TO GAME

Topic 2: Antigens $400 Question In opsonization, antigens that are coated with antibodies are susceptible to a. B cells. b. T helper cells. c. phagocytosis. d. complement. Answer = C ANSWER BACK TO GAME

Topic 2: Antigens $400 Answer In opsonization, antigens that are coated with antibodies are susceptible to a. B cells. b. T helper cells. c. phagocytosis. d. complement. BACK TO GAME

Topic 2: Antigens $500 Question IgG antibodies inactivate microbes by blocking their attachment to host cells in the binding process known as neutralization. agglutination. antibody-dependent cell-mediated cytotoxicity. opsonization. Answer = A ANSWER BACK TO GAME

Topic 2: Antigens $500 Answer IgG antibodies inactivate microbes by blocking their attachment to host cells in the binding process known as neutralization. agglutination. antibody-dependent cell-mediated cytotoxicity. opsonization. BACK TO GAME

Topic 3: Humoral Immunity $100 Question Approximately how many genes are associated with the diversity of the human immune system for recognizing the vast amount of possible antigens? hundreds thousands millions billions Answer = A ANSWER BACK TO GAME

Topic 3: Humoral Immunity $100 Answer Approximately how many genes are associated with the diversity of the human immune system for recognizing the vast amount of possible antigens? hundreds thousands millions billions BACK TO GAME

Topic 3: Humoral Immunity $200 Question What is the activation and proliferation of specific B cells termed? plasma cell selection clonal expansion plasma cell expansion clonal selection Answer = D ANSWER BACK TO GAME

Topic 3: Humoral Immunity $200 Answer What is the activation and proliferation of specific B cells termed? plasma cell selection clonal expansion plasma cell expansion clonal selection BACK TO GAME

Topic 3: Humoral Immunity $300 Question Plasma cells are formed after the proliferation of which type of cell? B cell T cell memory cell monocyte Answer = A ANSWER BACK TO GAME

Topic 3: Humoral Immunity $300 Answer Plasma cells are formed after the proliferation of which type of cell? B cell T cell memory cell monocyte BACK TO GAME

Topic 3: Humoral Immunity $400 Question A collection of genes that encode molecules of genetically diverse glycoproteins found on mammalian nucleated cells is called the complement. antibody-complement complex. interleukins. major histocompatibility complex. Answer = D ANSWER BACK TO GAME

Topic 3: Humoral Immunity $400 Answer A collection of genes that encode molecules of genetically diverse glycoproteins found on mammalian nucleated cells is called the complement. antibody-complement complex. interleukins. major histocompatibility complex. BACK TO GAME

Topic 3: Humoral Immunity $500 Question _____ is the changing of antibody classes without changing the antigenic specificity. Class switching Clonal selection Clonal specificity Class selection Answer = A ANSWER BACK TO GAME

Topic 3: Humoral Immunity $500 Answer _____ is the changing of antibody classes without changing the antigenic specificity. Class switching Clonal selection Clonal specificity Class selection BACK TO GAME

Topic 4: Cellular Immunity $100 Question Maturation of the T cells takes place in the bone marrow. liver. thymus. spleen. Answer = C ANSWER BACK TO GAME

Topic 4: Cellular Immunity $100 Answer Maturation of the T cells takes place in the bone marrow. liver. thymus. spleen. BACK TO GAME

Topic 4: Cellular Immunity $200 Question Where are MHC II proteins found, and what cells recognize them? all body cells; T helper cells all body cells; T cytotoxic cells APCs; T helper cells APCs; T cytotoxic cells Answer = C ANSWER BACK TO GAME

Topic 4: Cellular Immunity $200 Answer Where are MHC II proteins found, and what cells recognize them? a. all body cells; T helper cells b. all body cells; T cytotoxic cells c. APCs; T helper cells d. APCs; T cytotoxic cells BACK TO GAME

Topic 4: Cellular Immunity $300 Question T cells are classified by certain glycoproteins on their surface called granzymes. endogenous antigens. clusters of differentiation. interleukins. Answer = C ANSWER BACK TO GAME

Topic 4: Cellular Immunity $300 Answer T cells are classified by certain glycoproteins on their surface called granzymes. endogenous antigens. clusters of differentiation. interleukins. BACK TO GAME

Topic 4: Cellular Immunity $400 Question Which cells combat autoimmunity as their primary function? cytotoxic T lymphocytes T cytotoxic cells T helper cells T regulatory cells Answer = D ANSWER BACK TO GAME

Topic 4: Cellular Immunity $400 Answer Which cells combat autoimmunity as their primary function? a. cytotoxic T lymphocytes b. T cytotoxic cells c. T helper cells d. T regulatory cells BACK TO GAME

Topic 4: Cellular Immunity $500 Question Cytotoxic T lymphocytes attach to the target cell and release lysozymes. perforin. complement proteins. lytic enzymes. Answer =B ANSWER BACK TO GAME

Topic 4: Cellular Immunity $500 Answer Cytotoxic T lymphocytes attach to the target cell and release lysozymes. perforin. complement proteins. lytic enzymes. BACK TO GAME

Topic 5: Adaptive Immunity $100 Question The relative amount of antibody in the serum is referred to as the number of B cells. differential count. antibody titer. T cell count. Answer = C ANSWER BACK TO GAME

Topic 5: Adaptive Immunity $100 Answer The relative amount of antibody in the serum is referred to as the number of B cells. differential count. antibody titer. T cell count. BACK TO GAME

Topic 5: Adaptive Immunity $200 Question The antibody that is formed in the secondary response is mostly IgG. IgE. IgM. IgA. Answer = A ANSWER BACK TO GAME

Topic 5: Adaptive Immunity $200 Answer The antibody that is formed in the secondary response is mostly IgG. IgE. IgM. IgA. BACK TO GAME

Topic 5: Adaptive Immunity $300 Question A person who has had measles will develop _____ immunity. naturally acquired active naturally acquired passive artificially acquired active artificially acquired passive Answer = A ANSWER BACK TO GAME

Topic 5: Adaptive Immunity $300 Answer A person who has had measles will develop _____ immunity. naturally acquired active naturally acquired passive artificially acquired active artificially acquired passive BACK TO GAME

Topic 5: Adaptive Immunity $400 Question A toxoid, such as the tetanus toxoid, conveys _____ immunity. naturally acquired active naturally acquired passive artificially acquired active artificially acquired passive Answer = C ANSWER BACK TO GAME

Topic 5: Adaptive Immunity $400 Answer A toxoid, such as the tetanus toxoid, conveys _____ immunity. naturally acquired active naturally acquired passive artificially acquired active artificially acquired passive BACK TO GAME

Topic 5: Adaptive Immunity $500 Question What type of immunity is conveyed when exposed individuals are given antibodies by injection? naturally acquired active naturally acquired passive artificially acquired active artificially acquired passive Answer = D ANSWER BACK TO GAME

Topic 5: Adaptive Immunity $500 Answer What type of immunity is conveyed when exposed individuals are given antibodies by injection? naturally acquired active naturally acquired passive artificially acquired active artificially acquired passive Answer = D BACK TO GAME

FINAL ROUND Question Which antigen-presenting cells play a key role in helping your immune system differentiate self from nonself? neutrophils dendritic cells memory cells plasma cells Answer = B ANSWER BACK TO GAME

FINAL ROUND Answer Which antigen-presenting cells play a key role in helping your immune system differentiate self from nonself? neutrophils dendritic cells memory cells plasma cells BACK TO GAME