Obstestrics 성균관대학교 의과대학 m5 손의영 Pt ID : 10755559 김 0 경 30/F.

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Obstestrics 성균관대학교 의과대학 m5 손의영 Pt ID : 김 0 경 30/F

Chief Complain Amenorrhea for weeks with decreased Fetal movement (NST non-reactive) Onset :

Obstetric History Para : (1) - (0) - (0)(,) - (1)(0,1) 최종 월경 시작일 : 분만 예정일 :

Present Illness Prenatal check at SMC OBGY since 주 by Pf 노정래 Last Pap : 특이사항 (No) Serum screening test : Quad test (-) g OGTT (26+3wks) ▲ 146 mg/dL g OGTT (29+1wks) ( 78 - ▲ ▲ ) mg/dL CBC : 특이사항 (No)

Other History PMHx. HTN/DM/Tb/hepatitis/Allergy ( - / - / - / - / - ) Prev. GDM ( 이전 임신시 27 주경 진단 ) 약물력 : 엽산제, Oral iron, glibenclamide 2.5mg/d for 1 wk 수술력 : (No) FHx. 당뇨 : (+), 모친 고혈압 (-), 유전질환 (-) SHx. Marriage : 기혼 (26 세 ) smoking: no alcohol: no

Review of System Obstetric symptoms Fetal movement (Yes) Uterine contraction (Yes) : Irregular Vaginal bleeding (No) Watery vaginal discharge (No) General symptoms 임신 전 체중 : 53kg 현재 체중 : 61.7kg 그 외 이상 소견 없음

Physical Exam General appearance Not so ill looking Mental status : Alert Abdomen Palpitation : Distended d/t pregnancy Tenderness (No) Rebound tenderness (No)

Physical Exam 산과 진찰소견 FHR : Normal by USG Normal by Doppler (Heart rate bpm) Presenting part : Cephalic Cervix dilatation : Closed Effacement : NE Station : -1 Vaginal discharge : Normal Rupture of membrane (No) Vaginal bleeding (No)

Assessment Pregnancy : weeks c decreased FM (NST non-reactive) c GDM c prev. GDM

Plan 치료계획 :Intravenous Pitocin (Propess insertion 하지 않고 익일 pitocin start 하여 induction) 퇴원계획 : 자연분만 후 합병증 없으면 PP#2 퇴원

Hospital Course 분만 ( weeks) 분만 시간 : 11:18 Induction(Yes) Prostaglandin (No) Dinoprostone (No) Misoprostol (No) Oxytocin (Yes) Baby 1 성별 : 여아 출생시 체중 (3.07)kg Apgar score : 1min – (9), 5min – (10) MS (0) CN (0) GA ( No) : cord pH NR

Hospital Course PP#1 【검사명】 【단위】 【시행일】 【결과】 Hb, Blood g/dL :07 ▼ :38 ▼ Dressing done : episiotomy site clear, no hematoma 익일 퇴원 예정

Gestational Diabetes Classification Overt DM : 임신 전에 당뇨로 진단 된 경우 Gestational DM : 임신 중에 당뇨로 진단된 경우 Diagnosis of GDM Screening : 1hr 50g OGTT (PA 24~28 weeks) 140 이상이면 확진 검사 ! Diagnosis : Overnight fasting 후 100g OGTT fasting/1h/2h/3h – 105/190/165/145 이 중 2 개 이상 기준치 초과 시 확진 !

Gestational Diabetes

GDM – Risk & Strategy 평가는 반드시 첫 번째 PN visit 때 이루어져야 한다. Low risk : 다음을 모두 만족 Member of an ethnic group with a low prevalence of GDM No known diabetesin 1 st -degree relatives Age < 25 years Weight normal before pregnancy Weight normal at birth No history of abnormal glucose metabolism No history of poor obstetrical outcome Low risk 에서는 Routine serum glucose 측정 안 해도 된다.

GDM – Risk & Strategy Average risk : PA 24~28 주에 평가 Two-step : 50g OGTT  100g OGTT One-step : 100g OGTT on all subjects High risk : 가능한 빨리 혈당 검사 한다. 다음 중 한 가지 이상 만족 Severe obesity Family History of T2DM Personal History of GDM

GDM – Complications Maternal Effects Diabetic retinopathy Diabetic nephropathy Diabetic neuropathy C-sec rate ↑, maternal risk ↑ Pre-eclampsia Ketoacidosis Infection : genital tract, respiratory tract Difficult delivery d/t large fetus

GDM – Complications Fetal Effects Abortion Malformation Hydramnios Respiratory distress Hypoglycemia Hypocalcemia Hyperbilirubinemia Cardiac hypertrophy Macrosomia

GDM – Treatments Diet Exercise Insulin : FBS < 95 mg/dL, PP2 < 120 mg/dL 으로 유지되지 않으면 투여 (ADA, 2006) 분만 : near term 에 분만 PA 가 확실하면 38 주 이후 분만 PA 가 불확실하면 38 주 경에 L/S ratio 측정하여 L/S ratio ≥ 2 이면 분만 심한 고혈압이 있으면 L/S ratio < 2 이어도 분만

References Williams Obstetrics, 23 rd Edition