EXTRACTING ARTERIAL BLOOD CURVE FROM PET IMAGE Images containing abdominal aorta.

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Presentation transcript:

EXTRACTING ARTERIAL BLOOD CURVE FROM PET IMAGE Images containing abdominal aorta

why  missing blood data  noninvasive alternative high costs of arterial sampling other problems with arterial sampling more reliable than arterialised venous sampling

method - what are we fitting  only once diameter of the vessel (needs initial value)  for all frames separately center of the vessel activity inside vessel activity of the surrounding area

how Known: C I =activity in PET image Unknown: C B =final input TAC C BG =background activity C A =activity inside arteria C I =(C A -C BG )*K+C BG => K distance from the centre of vessel

Adipose tissue study

problems & ideas  results are very dependent on diameter value  2D convolution might be used for testing

References Germano et al.: Use of Abdominal Aorta for Arterial Input Function Determination in Hepatic and Renal PET Studies: J Nucl Med 1992; 33: