Indeterminate Leprosy earliest and mildest form of the disease few numbers of hypopigmented macules (cutaneous lesions) loss of sensation is rare. most cases progress into a later form, although patients with strong immunity may either clear the infection on their own or persist in this form without progressing.

Tuberculoid Leprosy one large red patch with well-defined raised borders or a large hypopigmented asymmetrical spot lesions become dry and hairless loss of sensation may occur at site of some lesions tender, thickened nerves with subsequent loss of function are common spontaneous resolution may occur in a few years or it may progress to borderline or rarely lepromatous types

Tuberculoid Leprosy organisms present at low to undetectable levels low infectivity granulomas and local inflammation peripheral nerve damage normal serum immunoglobulin levels normal T – cell responsiveness specific response to M. leprae antigens

Borderline Tuberculoid Leprosy similar to tuberculoid type except that lesions are smaller and more numerous cutaneous lesions are numerous and less well defined anesthesis is less severe disease may stay in this stage or convert back to tuberculoid form, or progress

Borderline Tuberculoid Leprosy