MBV2010/BIO2140 Colloquium, May 7

RULES Multiple choice Only one correct answer 30-60 seconds to answer No textbook, computer, mobile phone, please There will be a prize for the group with the most correct answers.

1 A eukaryotic gene is most likely to be transcribed if it is located in A Telomeres B Heterochromatin C Euchromatin D Centromeres

1 A eukaryotic gene is most likely to be transcribed if it is located in A Telomeres B Heterochromatin C Euchromatin D Centromeres

2 Riboswitches A Are found in RNA B Are found in DNA C Regulate only transcription D Regulate only translation

2 Riboswitches A Are found in RNA B Are found in DNA C Regulate only transcription D Regulate only translation

3 Pre-microRNAs can be encoded in A introns B noncoding regions of a gene C coding regions D all of the above

3 Pre-microRNAs can be encoded in A introns B noncoding sequences C coding regions D all of the above

4 MicroRNA genes are transcribed by A RNA polymerase I B RNA polymerase II C RNA polymerase III D RNA polymerase V

4 MicroRNA genes are transcribed by A RNA polymerase I B RNA polymerase II C RNA polymerase III D RNA polymerase V

5 Which proteins make up the Microprocessor complex? A Pasha and Drosha B Dicer and Drosha C Dicer and Argonaute D Pasha and Dicer

5 Which proteins make up the Microprocessor complex? A Pasha and Drosha B Dicer and Drosha C Dicer and Argonaute D Pasha and Dicer

6 Which proteins have a PAZ domain? A Drosha and Dicer B Dicer and Argonaute C Argonaute and Drosha D Drosha and Pasha PAZ stands for three proteins that contain this domain.

6 Which proteins have a PAZ domain? PAZ stands for three proteins that contain this domain: Piwi, Argonaute, and Zwille A Drosha and Dicer B Dicer and Argonaute C Argonaute and Drosha D Drosha and Pasha

7 The long noncoding RNA Xist A functions in the cytoplasm B is transcribed from a gene called Tsix C coats the chromosome it is transcribed from D induces formation of euchromatin

7 The long noncoding RNA Xist A functions in the cytoplasm B is transcribed from a gene called Tsix C coats the chromosome it is transcribed from D induces formation of euchromatin

8 Gal80 A is a regulator of transcription B is a repressor of transcription C binds to DNA D binds to RNA

8 Gal80 A is a regulator of transcription B is a repressor of transcription C binds to DNA D binds to RNA

9 PIWI-interaction RNAs (piRNAs) A are bound by the RISC complex B are about 200 nucleotides long C are present in prokaryotes D regulate transcription

9 PIWI-interaction RNAs (piRNAs) A are bound by the RISC complex B are about 200 nucleotides long C are present in prokaryotes D regulate transcription

10 The size of microRNAs varies between A 11-17 nucleotides B 19-25 nucleotides C 22-28 nucleotides D 25-30 nucleotides

10 The size of microRNAs varies between A 11-17 nucleotides B 19-25 nucleotides C 22-28 nucleotides D 25-30 nucleotides

11 Polycomb A is a repressor of transcription B is an activator of transcription C methylates DNA D deacetylates histones

11 Polycomb A is a repressor of transcription B is an activator of transcription C methylates DNA D deacetylates histones