Regrowing hair with laser and light sources: Is this practical? Michael R Hamblin PhD

near infrared light extracellular matrix deposition growth factor production cell proliferation & motility anti-apoptosis and pro-survival Gene transcription signaling Mechanisms of low-level light therapy

Literature Review

Low Level Light Therapy for Hair Regrowth 1.Does it work in androgenetic alopecia? 2.What is best wavelength? 3.What is best fluence/irradiance? 4.Do you need a laser? 5.How often should light be repeated? 6.Other parameters - pulsing, polarization? 7.Does it work for alopecia areata? 8.Does it work in women? 9.Does it work for chemotherapy? 10. What is best way to deliver light?

Summary and conclusion Low level light mechanisms are beginning to be understood Evidence exists for laser-induced hair growth Follicles can be rescued from dying and stimulated into anagen Optimum wavelength, laser or LED, irradiance, fluence and treatment repetition need to be determined Different patients may need different dosimetry Plethora of devices appearing on market Minimal number of clinical studies