The Endocrine System The Pituitary

Low magnification – the entire Pituitary Gland Posterior Pituitary Pars Intermedia Anterior Pituitary Pars TuberalisPituitary Stalk

High mag of the Anterior Pituitary – note eosinophilic and basophilic cells

Growth HormoneACTH Immunohistochemictry of the Anterior Pituitary

TEM of the Anterior Pituitary – note different granule morphology C – corticotrophs (ACTH); G – gonadotrophs (FSH,LH) S – somatotrophs (growth hormone); T Thyrotrophs (TSH) ; F – fenestrated capillary

High mag of the Posterior Pituitary – neurons, capillaries, and pituicytes

High mag of the Posterior Pituitary – note Herring Bodies (arrow)

TEM of the Posterior Pituitary UN -unmyelinated neuron; asterisks – Herring Body

The Thyroid & Parathyroids

High mag of thyroid follicles – note Parafollicular or C-Cells (arrows)

Low Magnification of the Parathyroid Gland

Parathyroid Gland – note small dark staining chief cells and larger, eosinophilic oxyphil cells

The Adrenal Glands

Low magnification of the Adrenal Gland Medulla Cortex

Adrenal Cortex Zona Glomerulosa Zona Fasciculata Zona Reticularis

Adrenal Cortex Zona Glomerulosa (clumps, cords, and follicle like structures Zona Fasciculata (cords of spongiocytes)

Adrenal Gland Zona Fasciculata cords of spongiocytes Zona Reticularis darker staining cells

Adrenal Medulla

The Islets of Langerhan

Low magnification of the Pancreas with Islets of Langerhans (arrows)

High mag of an Islet – note Beta cells and more eosinophilic Alpha2 cells Acini Alpha Cells

GlucagonInsulin Immunohistochemistry of a pancrearic Islet of Langerhans

Pineal Body The Seat of the Soul The Third Eye

Pineal Gland N – neuroglia P –pinealocytes S – Brain Sand