1 setting standards for prescribing Dr Keron Fletcher.

Slides:



Advertisements
Similar presentations
Abnormal Psychology Overview. Intro What does it mean to be normal? What does it mean to be normal? Has there ever been a time in your life where you.
Advertisements

If client wants to know more about vasectomy, go to next page.
Illinois Department of Children and Family Services, Pathways to Strengthening and Supporting Families Program April 5, 2010 Division of Service Support,
0 - 0.
2 pt 3 pt 4 pt 5 pt 1 pt 2 pt 3 pt 4 pt 5 pt 1 pt 2 pt 3 pt 4 pt 5 pt 1 pt 2 pt 3 pt 4 pt 5 pt 1 pt 2 pt 3 pt 4 pt 5 pt 1 pt Time Money AdditionSubtraction.
2 pt 3 pt 4 pt 5 pt 1 pt 2 pt 3 pt 4 pt 5 pt 1 pt 2 pt 3 pt 4 pt 5 pt 1 pt 2 pt 3 pt 4 pt 5 pt 1 pt 2 pt 3 pt 4 pt 5 pt 1 pt ShapesPatterns Counting Number.
Addition Facts
What to do about those benzos?!? Chris Ford GP & Clinical Director SMMGP 4 TH West Midlands Conference Birmingham 25/06/10.
Annie Steele Lisa Copeland 25 th June 2010 Primary care for people who happen to have a drug problem.
Implementing NICE guidance
Introduction to Drug Misuse Les Goldman. Objectives Gain basic knowledge of Common current patterns of drug misuse Local referral pathways Available treatments.
Alcohol misuse - a GP approach 1. 2 Objectives Improve confidence in Detection Assessment Management of problem drinking Improve confidence in Detection.
International meeting
1 0N-SITE TREATMENT OF HEPATITIS C - A PILOT STUDY Shay Keating, MB, PhD Medical Officer.
PKU in adolescents and adults
IMPACT report - SANANIM Bratislava; October 17,
IMPACT report - SANANIM Prague; February 21,
Glasgow Involvement Group Views from injecting drugs users in Glasgow Pathways to Treatment and Care Conference Stirling Royal Infirmary 30 th September.
Addressing Hypnotic medicines use in primary care
Adding Up In Chunks.
UNIT 2: SOLVING EQUATIONS AND INEQUALITIES SOLVE EACH OF THE FOLLOWING EQUATIONS FOR y. # x + 5 y = x 5 y = 2 x y = 2 x y.
Mady Chalk, PhD., MSW Treatment Research Institute November, 2013.
Addition 1’s to 20.
Prescription Drug Overdose National Perspective
Week 1.
Let’s take a 15 minute break Please be back on time.
Speak Up for Safety Dr. Susan Strauss Harassment & Bullying Consultant November 9, 2012.
Handling (and Preventing) Missing Data in RCTs ASENT March 7, 2009 Janet Wittes Statistics Collaborative.
Bottoms Up Factoring. Start with the X-box 3-9 Product Sum
Phase 3: Intervention Site Training
Click the arrows to advance forward and backward. Click the Next link below to advance to the assessment. The A B C & D’s of Suicide Assessment and Clinical.
Late Stabilization & Maintenance Phase of Treatment.
Respiratory Care in Children Better Care for Better Outcomes Dr Duncan Keeley GP Thame Thames Valley Strategic Clinical Network.
Effective Risk Management Strategies in Outpatient Methadone Treatment: Clinical Guidelines and Liability Prevention Curriculum MODULE 5 Take-Home Medication.
Smoking Cessation. Opportunity for Physicians 70 percent of smokers want to quit. Without assistance only 5 percent are able to quit. Most try to quit.
Module 4: Interaction of. Objectives To be aware of the possible reasons why dual diagnosis occurs To be aware of the specific effects of substances on.
Injectable Opioid Treatment in England Clinical Experience Rob van der Waal.
Copyright Alcohol Medical Scholars Program 1 Opioid Agonist Treatment: “Trading one substance for another?” Joseph Sakai, M.D.
Monitoring & Supporting use. Session 3 Describe what is involved in ordering prescriptions and collecting medicines from the pharmacy. Describe how medicines.
1 British Guideline on the Management of Asthma BTS/SIGN British Guideline on the Management of Asthma, May 2008 Introduction Diagnosis Non-pharmacological.
Diagnosis And Treatment Of Prescription Opioid Dependence Steven W. Clay, D.O. Associate Professor, Department of Family Medicine Ohio University College.
Following Your Treatment Plan. Taking your medication is an important part of your treatment. 2.
BUPRENORPHINE TREATMENT: A TRAINING FOR MULTIDISCIPLINARY ADDICTION PROFESSIONALS Module III – Buprenorphine 101.
Good Prescribing to support Criminal Justice Interventions
SOHO RAPID ACCESS CLINIC. AIMS: n To provide a client focussed, low threshold flexible prescribing service. n To offer an easily accessible assessment.
Dr. Avinash De Sousa.  State government aided hospital.  Private psychiatric set up – nursing home.  Out patient private practice.  Private general.
Increasing Access to Pharmacotherapy Jonathan P. Winickoff, MD, MPH Associate Professor in Pediatrics Harvard Medical School April 26, 2013.
An approach to maintenance Benzodiazepine prescribing Dr Malcolm Bruce Consultant Psychiatrist in Addiction NHS Lothian
 Methadone is prescribed to relieve moderate to severe pain that has not been relieved by non-narcotic pain relievers.
Problem Behaviors Norman Wetterau. Less serious Ran of out pills three days early After one year lost pills Had a headache and a friend gave her a vicodin.
Tom Waddell Urban Health Clinic: Patients Using Controlled Medicines* If you are taking controlled medicines, your safety is our highest priority! Our.
Don Teater MD Medical Advisor National Safety Council Itasca, IL Medical Provider Behavioral Health Group Asheville, NC Medical Provider Meridian Behavioral.
Weaning off BENZODIAZEPINES After Long-Term Use By Dr Sadaf Cheema GPST2.
Buprenorphine {Suboxone®, Subutex®}
Audit of psychotropic medication prescribing in EMI nursing homes in Monmouthshire Dr Pauline Ruth Dr Rui Zheng Dr Arpita Chakraborty Dr Usman Mansoor.
Detox workshop Susanna Lawrence October Aim and objectives  Create consistent, evidence based process for opiate, alcohol and benzodiazepine detoxes.
If you are concerned about a young person’s alcohol or drug use call Compass on for free confidential help and support. FALSE: Alcohol is.
Specialist service provision. Who is involved in specialist services? Statutory services –Run by NHS and Social Care, these deliver medical and psychosocial.
Suboxone and Opioid Trends Joseph Merrill M.D., M.P.H. University of Washington June 16, 2009.
Current Concepts in Pain Management
WITHDRAWING NIV AT THE END OF LIFE IN MOTOR NEURONE DISEASE
Prescribing.
Fever and Antipyretic use in children Clinical report AAP 2011
Catherine McShane Project Manager Dietitian
Low risk of sexual dysfunction versus placebo
Low risk of sexual dysfunction versus placebo
Guideline for the Treatment of Alcohol Use Disorder in the Outpatient Setting with Intramuscular Naltrexone Assess Candidacy for IM Naltrexone Meets DMS-V.
Drugs are chemicals which change the way your body works.
Let’s talk medicines safety
Receptor Sends Pain Signal to the Brain
Presentation transcript:

1 setting standards for prescribing Dr Keron Fletcher

2 standards of what? clinical effectiveness clinical safety clinical risk cost-effectiveness

3 standards Average DOSE of methadone per clinic (as a proxy for clinical effectiveness) PICK-UP regimes, especially % supervised (as a proxy for clinical safety) BENZODIAZEPINE prescribing – or lack of (as a proxy for clinical risk) METHADONE vs SUBUTEX (as a proxy for cost-effectiveness)

4 standard 1 - effectiveness: dose of methadone P 49: –Following the first week, doses can continue to be increased incrementally up to a total of between mg a day, and occasionally more – a level at which the patient reports feeling comfortable and is no longer using illicit heroin –Q: How do you assess feeling comfortable?

5 methadone – feeling comfortable no withdrawal symptoms for 24 hours –How do you feel one hour before you take your methadone? –Do you feel as comfortable one hour before you take your methadone as you do one hour afterwards? CLUE: patient goes to chemist the moment it opens CLUE: the patient sleeps poorly CLUE: the patient uses heroin soon after waking

6 methadone – feeling comfortable patient feels satisfied –Do you find yourself thinking about heroin? –Do you feel any craving? EXPLANATION: if you are hungry and have a sandwich it will stop you feeling hungry but you might still want more. If you are hungry and have a good meal its much easier to say no to the offer of something else.

7 methadone – feeling comfortable blocks effects of heroin –Q: If you use heroin do you get any benefit from it? –Q: Does heroin stop you feeling rough? –Q: Does heroin give you a buzz?? EXPLANATION: the proper dose of methadone fills up all of your receptors to that heroin cant do anything to you CLUE: if the patient says that buying heroin is now a waste of money – youve got the dose right!

8 methadone – feeling comfortable does not cause sedation –If so, reduce dose.

9 standard 1 - effectiveness mean dose of methadone in a clinic: > 60mls ??? av. dose in UK has risen over the last 10 years from 45 – 55mg/day

10 standard 2 – safety: pick-up regime P 51: –Take home doses should not normally be prescribed where: Dose not yet stable Use of illicit drugs or benzodiazepines, heavy alcohol use Psychiatric illness or risk of self-harm Risk of inappropriate use or diversion of medication Concerns about safe storage at home and risks to children

11 standard 2 – safety % patients on supervision = % patients not producing 3 consecutive clear urines + up to an additional 20% + 20% to allow for other factors –Psychiatric problems/self harm –Child care problems –Alcohol/benzodiazepines –Concerns about diversion –???

12 standard 3 - risk: benzodiazepines P 60 –…there is increasing evidence that long-term prescribing (especially of more than 30 mg diazepam per day) may cause harm. in the treatment of bzp dependence: –To prevent symptoms of withdrawal, the clinician should continue the prescription but the dose should gradually be reduced to zero. Only very rarely should doses of more than 30 mg diazepam per day be prescribed.

13 standard 3: risk % patients on prescribed benzodiazepines = < 10% ???

14 standard 4 – cost effectiveness: methadone vs subutex P 48 NICE recommendation (TA 114, 2007): If both drugs are equally suitable, methadone should be prescribed as the first choice. Reason – primarily cost, although some evidence that methadone is better at retaining people in treatment

15 shropshire/powys outcome data % Time (months) Х 2 P = t-test P = methbupmethbup retained 3 months 9055 <0.001 *** retained 12 months 5826 <0.001 *** clear urine <0.001 *** ** stop injecting < ** 0.02 * take home <0.001 *** * stay true 8018 <0.001 ***

16 shropshire/powys outcome data % Time (months) Х 2 P = t-test P = methbupmethbup retained 3 months 9055 <0.001 *** retained 12 months 5826 <0.001 *** clear urine <0.001 *** ** stop injecting < ** 0.02 * take home <0.001 *** * stay true 8018 <0.001 ***

17 summary of audit Methadone was significantly better than Subutex at: –Retention in treatment at 3 & 12 months –Producing a clear urine sample –Stopping injecting –Achieving take-home doses –Satisfying patients Subutex produced poorer but quicker results: –Clear urine –Stop injecting –Achieving take-home BUT: –Subutex patients are more likely to be non-injectors. When compared to a non-injecting methadone group the time to achieve the above 3 criteria is not significantly different

18 standard 4 – methadone:Subutex no more than 20% of prescription should be for Subutex???? everyone who is prescribed Subutex must have the clinical reasons for not prescribing methadone written in the notes???

19 monitoring tools the front sheet the summary sheet

20 SUBSTITUTE PRESCRIBING – St Austins Name:____________________________________________________________________________________ PHARMACIST: ___________________________________________________________________________ ___________________________________________________________________________ TEL NO: ________________________________FAX NO:___________________________________ PICK UP DAYS ___________________________________________________________________________ DateDoee 1mg/ ml Form Next Scrp Due Next Appt URINE RESULTS Inj Freq Pick up Hep B Jab MeOpAmBzp (I) Bzp (P) Coc 04/02/1030,40, 50 Meth11/02/ x Daily 7s1 11/02/1060,70, 80 Meth04/03/ x Daily 7s2 02/03/1090Meth24/06/ s3 Form:Meth = MethadoneSBX = Subutex Pick-up: 7s = daily supervised 7 = daily 3 = 3 x weekly 2 = 2 x weekly 1 = weekly Benzos:I = illicitP = prescribed

21 summary sheets shared care monitoring group 2005: ClMean dosePick-ups per week% S = supervised Tested for hep viruses Immuns against hep viruses Opiates in urineOther drugs in urine iv use at start Still iv use MthSb7S73213neg3pos3neg3pos LW %79%58%11%68%0%68%16% xx % 0%100%0%100%40% yy % 30%50%70%10%60%40%

22 summary sheets shared care monitoring group 2008: ClMean dosePick-ups per week % S = supervised Opiates in urine Other drugs in urine iv use at start Still iv use MthSb7S73213neg3pos3neg3pos LW %11%68%0%68%16% xx % 57%86%29% yy %0%55%0%18%9%

23 four suggested local standards prescribing 1.effectiveness: average dose of methadone 1mg/ml in a clinic should be greater than 60mls 2. safety: % patients on daily supervised consumptions should equal the % patients still using illicit drugs PLUS 20% to allow for other safety factors 3. risk: % patients receiving prescribed benzodiazepines should be less than 10% 4. cost effectiveness: % patients prescribed Subutex should be less than 20% and/or everyone who is prescribed Subutex must have the clinical reasons for not prescribing methadone written in the notes