What is a computer virus? –How similar is it to a virus that effects your health? Copyright © 2010 Ryan P. Murphy This unit belongs to Ryan P. Murphy Copyright 2010 This unit belongs to Ryan P. Murphy Copyright 2010
A computer virus: A software program capable of reproducing itself and usually capable of causing great harm to files or other programs on the same computer.
Copyright © 2010 Ryan P. Murphy
"The first chapter of The Hot Zone is one of the most horrifying things I've read in my whole life--and then it gets worse. That's what I keep marveling over: it keeps getting worse. What a remarkable piece of work." --Stephen King
Activity! Reading some selections from the first chapter of the Hot Zone by Richard Preston. –Caution! Book is very graphic. –Ebola is one of the most gruesome and deadliest viruses on the planet. –Link to a teaser from first chapter – Copyright © 2010 Ryan P. Murphy
Ebola virus
Video Link! Ebola (1:52 min) –How is spread? From the forest, and through the human population? – Copyright © 2010 Ryan P. Murphy
Serious Infectious Diseases: An Introduction and history through humanity. Copyright © 2010 Ryan P. Murphy
Infectious Diseases will include Infectious Diseases will include Viruses Viruses Bacteria Bacteria Parasites Parasites Copyright © 2010 Ryan P. Murphy
Infectious Diseases will include Infectious Diseases will include Viruses Viruses Bacteria Bacteria Parasites Parasites Copyright © 2010 Ryan P. Murphy
Infectious Diseases will include Infectious Diseases will include Viruses Viruses Bacteria Bacteria Parasites Parasites Copyright © 2010 Ryan P. Murphy
Infectious Diseases will include Infectious Diseases will include Viruses Viruses Bacteria Bacteria Parasites Parasites Copyright © 2010 Ryan P. Murphy
Infectious Diseases will include Infectious Diseases will include Viruses Viruses Bacteria Bacteria Parasites Parasites Copyright © 2010 Ryan P. Murphy
In the Extreme East, China dwindled from 123 million inhabitants at the beginning of the 13th century to just 65 million during the 14th century, because of the plague. Copyright © 2010 Ryan P. Murphy
In the Extreme East, China dwindled from 123 million inhabitants at the beginning of the 13th century to just 65 million during the 14th century, because of the plague. –You do the math… Copyright © 2010 Ryan P. Murphy
In the Extreme East, China dwindled from 123 million inhabitants at the beginning of the 13th century to just 65 million during the 14th century, because of the plague. –You do the math… Copyright © 2010 Ryan P. Murphy
The smallpox virus. Copyright © 2010 Ryan P. Murphy
Polio (Virus)– Killed and Crippled Millions until about 1958
Another great vaccine saved millions from Polio in 1955.
HIV (Virus) – 60 Million Currently Infected
Malaria (Plasmodium Parasite) is found in 500 million people. 300 million cases are very severe. Copyright © 2010 Ryan P. Murphy
Malaria (Plasmodium Parasite) is found in 500 million people. 300 million cases are very severe. –Hundreds of million die. Most of which are children. Copyright © 2010 Ryan P. Murphy
Viruses may have evolved with the first cells but their evolution is difficult to trace because they don’t create fossils.
Viruses infect just about every type of life form.
A virus is a nucleic acid A virus is a nucleic acid Copyright © 2010 Ryan P. Murphy
A virus is a nucleic acid (DNA or RNA) A virus is a nucleic acid (DNA or RNA) Copyright © 2010 Ryan P. Murphy
A virus is a nucleic acid (DNA or RNA) A virus is a nucleic acid (DNA or RNA) Copyright © 2010 Ryan P. Murphy
A virus is a nucleic acid (DNA or RNA) enclosed in a protein (capsid) shell or coat. A virus is a nucleic acid (DNA or RNA) enclosed in a protein (capsid) shell or coat. Copyright © 2010 Ryan P. Murphy
The capsid coat can have several shapes, and may further be surrounded by an envelope.
–The envelope is made up of lipids and is usually imbedded with proteins which help the virus recognize its host cell.
The capsid coat can have several shapes, and may further be surrounded by an envelope. –The envelope is made up of lipids and is usually imbedded with proteins which help the virus recognize its host cell.
The capsid coat can have several shapes, and may further be surrounded by an envelope. –The envelope is made up of lipids and is usually imbedded with proteins which help the virus recognize its host cell.
The capsid coat can have several shapes, and may further be surrounded by an envelope. –The envelope is made up of lipids and is usually imbedded with proteins which help the virus recognize its host cell.
The capsid coat can have several shapes, and may further be surrounded by an envelope. –The envelope is made up of lipids and is usually imbedded with proteins which help the virus recognize its host cell.
Viruses are extremely small; approximately nanometers in diameter. Viruses are extremely small; approximately nanometers in diameter. Copyright © 2010 Ryan P. Murphy
Viruses are extremely small; approximately nanometers in diameter. Viruses are extremely small; approximately nanometers in diameter. Copyright © 2010 Ryan P. Murphy
Viruses are extremely small; approximately nanometers in diameter. Viruses are extremely small; approximately nanometers in diameter. Copyright © 2010 Ryan P. Murphy
Viruses are extremely small; approximately nanometers in diameter. Viruses are extremely small; approximately nanometers in diameter. Copyright © 2010 Ryan P. Murphy
Viruses are extremely small; approximately nanometers in diameter. Viruses are extremely small; approximately nanometers in diameter. Copyright © 2010 Ryan P. Murphy Learn more about the structure of a virus at… htm htm htm
Viruses: They can reproduce only by invading and taking over other cells. Viruses: They can reproduce only by invading and taking over other cells.
They lack the cellular machinery for self reproduction. They lack the cellular machinery for self reproduction.
Question - Are Viruses living? Why or why not? Copyright © 2010 Ryan P. Murphy
Video! Animation of a T4 Bacteriophage landing on a bacterium. –Are viruses living or non-living? – Copyright © 2010 Ryan P. Murphy
Why viruses are not living… Why viruses are not living… Copyright © 2010 Ryan P. Murphy
Viruses are not made of cells. Viruses are not made of cells. Copyright © 2010 Ryan P. Murphy
They have no cell parts. They have no cell parts. Copyright © 2010 Ryan P. Murphy
They do not grow and develop. They do not grow and develop. Copyright © 2010 Ryan P. Murphy
They do not respond to their environment. They do not respond to their environment. Copyright © 2010 Ryan P. Murphy
Viruses are sort of living because.. Viruses are sort of living because Copyright © 2010 Ryan P. Murphy
Viruses Replicate, Viruses Replicate, Copyright © 2010 Ryan P. Murphy
Viruses Replicate, but only by invading living cells, not by themselves. Viruses Replicate, but only by invading living cells, not by themselves. Copyright © 2010 Ryan P. Murphy
They Evolve / Mutate. They Evolve / Mutate. Copyright © 2010 Ryan P. Murphy
Limited movement. Limited movement. Copyright © 2010 Ryan P. Murphy
Types of Viruses Types of Viruses Copyright © 2010 Ryan P. Murphy
Round Shaped (Envelope) Round Shaped (Envelope) Copyright © 2010 Ryan P. Murphy
HIV, Polio, Influenza, Common Cold
Rod-Shaped (Helical) Rod-Shaped (Helical) Copyright © 2010 Ryan P. Murphy
Ebola
Retrovirus: A single-stranded RNA virus containing an enzyme that allows for a reversal of genetic transcription. –From RNA to DNA rather than the usual DNA to RNA.
Retrovirus: A single-stranded RNA virus containing an enzyme that allows for a reversal of genetic transcription. –From RNA to DNA rather than the usual DNA to RNA.
Lytic viruses: Causes host cell to split / die as virus replicates. Lytic viruses: Causes host cell to split / die as virus replicates. Copyright © 2010 Ryan P. Murphy
Viral DNA / RNA enters into cellViral DNA / RNA enters into cell Copyright © 2010 Ryan P. Murphy
DNA / RNA replicates.DNA / RNA replicates. Copyright © 2010 Ryan P. Murphy The viral DNA then takes over control (hijacks) and has the cell make viral proteins.
DNA / RNA replicates.DNA / RNA replicates. Copyright © 2010 Ryan P. Murphy
New virus parts are constructed.New virus parts are constructed. Copyright © 2010 Ryan P. Murphy