Prof. Massimo Massi Benedetti Chairman IDF European Region Department of Internal Medicine -University of Perugia (I) THE DIABETIC TIME BOMB IN EUROPE.

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Prof. Massimo Massi Benedetti Chairman IDF European Region Department of Internal Medicine -University of Perugia (I) THE DIABETIC TIME BOMB IN EUROPE “Round Table” European Parliament Brussels Members Salon Tuesday 5th November 2002

THE INTERNATIONAL DIABETES FEDERATION The mission of the International Diabetes Federation is to work with our member associations to enhance the lives of people with diabetes

IDF Regions

Total population: 655 millions People with diabetes:22.5 millions Member associations:59 Countries represented:41 IDF European Region

The estimated prevalence and numbers of type 2 diabetes mellitus by IDF region, year 2000

Differences in the prevalence of type 2 diabetes among selected ethnic groups

Prevalence in different countries in the year. (%)  1994  2000

Diabetes prevalence in different age classes Prevalence (%) Age classes

Proportion of adolescent obesity Whites Blacks AmericanIndians % Obese Barry et al, J. Nutr

Estimates of magnitude of T2DM in North American children StudyYearAgeEstimates* (Years)(%) San Diego, CA Cincinnati, OH San Antonio, TX Ventura, CA Charleston, SC *Percentage of T2DM among new cases of diabetes

Impaired Glucose Tolerance IGT is characterised by raised blood glucose after meals (post-prandial hyperglycaemia), with near-normal fasting blood glucose IGT usually progresses to type 2 diabetes

Results from the Hoorn Study: 28 % of the subjects with IGT at baseline have developed type 2 diabetes within 2 years of study duration This is equivalent to a progression rate of 13.8% per year Rate of progression of impaired glucose tolerance to type 2 diabetes

Diabetes mellitus Regional estimates Africa Americas Eastern Europe South-Est Western Mediterranean Asia Pacific Million of individuals