Supplemental Figure 1 Relative intensities Acetone Chloroform Ethanol Hexane Isopropanol Acetic acid Methanol t-BME Toluene Water Xylene No wash , Heme group Mass-to-charge (m/z)

EthanolIsopropanolAcetic acidWaterNo wash Relative TIC Day 1 Day 2 Day 4 Day 7 Day 14 Supplemental Figure 2

Ethanol Isopropanol Acetic acid Water Relative intensities Day 2 Day 7 Mass-to-charge (m/z) Supplemental Figure 3

Mass-to-charge (m/z) Relative intensities Day 2 Day 4 Day 7 Day Day of Analysis Relative Protein TIC Supplemental Figure 4