Chapter 2 Chemistry Comes Alive: Part A

Matter Anything that has mass and occupies space States of matter: 1.Solid—definite shape and volume 2.Liquid—definite volume, changeable shape 3.Gas—changeable shape and volume

Energy Capacity to do work or put matter into motion Types of energy: Kinetic—energy in action Potential—stored (inactive) energy PLAY Animation: Energy Concepts

Forms of Energy Chemical energy—stored in bonds of chemical substances Electrical energy—results from movement of charged particles Mechanical energy—directly involved in moving matter Radiant or electromagnetic energy—exhibits wavelike properties (i.e., visible light, ultraviolet light, and X-rays)

Energy Form Conversions Energy may be converted from one form to another Conversion is inefficient because some energy is “ lost ” as heat

Composition of Matter Elements Cannot be broken down by ordinary chemical means Each has unique properties: Physical properties Are detectable with our senses, or are measurable Chemical properties How atoms interact (bond) with one another

Composition of Matter Atoms Unique building blocks for each element Atomic symbol: one- or two-letter chemical shorthand for each element

Major Elements of the Human Body Oxygen (O) Carbon (C) Hydrogen (H) Nitrogen (N) About 96% of body mass

Lesser Elements of the Human Body About 3.9% of body mass: About 3.9% of body mass: Calcium (Ca), phosphorus (P), potassium (K), sulfur (S), sodium (Na), chlorine (Cl), magnesium (Mg), iodine (I), and iron (Fe)

Trace Elements of the Human Body < 0.01% of body mass: Part of enzymes, e.g., chromium (Cr), manganese (Mn), and zinc (Zn)

Atomic Structure Determined by numbers of subatomic particles Nucleus consists of neutrons and protons

Atomic Structure Neutrons No charge Mass = 1 atomic mass unit (amu) Protons Positive charge Mass = 1 amu

Atomic Structure Electrons Orbit nucleus Equal in number to protons in atom Negative charge 1/2000 the mass of a proton (0 amu)

Models of the Atom Orbital model: current model used by chemists Depicts probable regions of greatest electron density (an electron cloud) Useful for predicting chemical behavior of atoms

Models of the Atom Planetary model—oversimplified, outdated model Incorrectly depicts fixed circular electron paths Useful for illustrations (as in the text)

Copyright © 2010 Pearson Education, Inc. Figure 2.1 (a) Planetary model(b) Orbital model Helium atom 2 protons (p + ) 2 neutrons (n 0 ) 2 electrons (e – ) Helium atom 2 protons (p + ) 2 neutrons (n 0 ) 2 electrons (e – ) Nucleus ProtonNeutronElectron cloud Electron

Identifying Elements Atoms of different elements contain different numbers of subatomic particles Compare hydrogen, helium and lithium (next slide)

Copyright © 2010 Pearson Education, Inc. Figure 2.2 Proton Neutron Electron Helium (He) (2p + ; 2n 0 ; 2e – ) Lithium (Li) (3p + ; 4n 0 ; 3e – ) Hydrogen (H) (1p + ; 0n 0 ; 1e – )

Identifying Elements Atomic number = number of protons in nucleus

Identifying Elements Mass number = mass of the protons and neutrons Mass numbers of atoms of an element are not all identical Isotopes are structural variations of elements that differ in the number of neutrons they contain

Identifying Elements Atomic weight = average of mass numbers of all isotopes

Copyright © 2010 Pearson Education, Inc. Figure 2.3 Proton Neutron Electron Deuterium ( 2 H) (1p + ; 1n 0 ; 1e – ) Tritium ( 3 H) (1p + ; 2n 0 ; 1e – ) Hydrogen ( 1 H) (1p + ; 0n 0 ; 1e – )

Radioisotopes Spontaneous decay (radioactivity) Similar chemistry to stable isotopes Can be detected with scanners

Radioisotopes Valuable tools for biological research and medicine Cause damage to living tissue: Cause damage to living tissue: Useful against localized cancers Useful against localized cancers Radon from uranium decay causes lung cancer Radon from uranium decay causes lung cancer

Molecules and Compounds Most atoms combine chemically with other atoms to form molecules and compounds Most atoms combine chemically with other atoms to form molecules and compounds Molecule—two or more atoms bonded together (e.g., H 2 or C 6 H 12 O 6 ) Compound—two or more different kinds of atoms bonded together (e.g., C 6 H 12 O 6 )

Mixtures Most matter exists as mixtures Two or more components physically intermixed Three types of mixtures SolutionsColloidsSuspensions

Solutions Homogeneous mixtures Usually transparent, e.g., atmospheric air or seawater Solvent Present in greatest amount, usually a liquid Solute(s) Present in smaller amounts

Concentration of Solutions Expressed as Percent, or parts per 100 parts Milligrams per deciliter (mg/dl) Molarity, or moles per liter (M) 1 mole = the atomic weight of an element or molecular weight (sum of atomic weights) of a compound in grams 1 mole of any substance contains 6.02  molecules (Avogadro ’ s number)

Colloids and Suspensions Colloids (emulsions) Heterogeneous translucent mixtures, e.g., cytosol Large solute particles that do not settle out Undergo sol-gel transformations Suspensions: Heterogeneous mixtures, e.g., blood Large visible solutes tend to settle out

Copyright © 2010 Pearson Education, Inc. Figure 2.4 Solution Solute particles Solute particles Solute particles Solute particles are very tiny, do not settle out or scatter light. Colloid Solute particles are larger than in a solution and scatter light; do not settle out. Suspension Solute particles are very large, settle out, and may scatter light. Example Mineral water Example Gelatin Example Blood

Mixtures vs. Compounds Mixtures No chemical bonding between components Can be separated physically, such as by straining or filtering Heterogeneous or homogeneous Compounds Can be separated only by breaking bonds All are homogeneous

Chemical Bonds Electrons occupy up to seven electron shells (energy levels) around nucleus Octet rule: Except for the first shell which is full with two electrons, atoms interact in a manner to have eight electrons in their outermost energy level (valence shell)

Chemically Inert Elements Stable and unreactive Outermost energy level fully occupied or contains eight electrons

Copyright © 2010 Pearson Education, Inc. Figure 2.5a Helium (He) (2p + ; 2n 0 ; 2e – ) Neon (Ne) (10p + ; 10n 0 ; 10e – ) 2e 8e (a) Chemically inert elements Outermost energy level (valence shell) complete

Chemically Reactive Elements Outermost energy level not fully occupied by electrons Tend to gain, lose, or share electrons (form bonds) with other atoms to achieve stability

Copyright © 2010 Pearson Education, Inc. Figure 2.5b 2e 4e 2e 8e 1e (b) Chemically reactive elements Outermost energy level (valence shell) incomplete Hydrogen (H) (1p + ; 0n 0 ; 1e – ) Carbon (C) (6p + ; 6n 0 ; 6e – ) 1e Oxygen (O) (8p + ; 8n 0 ; 8e – ) Sodium (Na) (11p + ; 12n 0 ; 11e – ) 2e 6e

Types of Chemical Bonds IonicCovalentHydrogen

Ionic Bonds Ions are formed by transfer of valence shell electrons between atoms Anions (– charge) have gained one or more electrons Cations (+ charge) have lost one or more electrons Attraction of opposite charges results in an ionic bond

Copyright © 2010 Pearson Education, Inc. Figure 2.6a-b Sodium atom (Na) (11p + ; 12n 0 ; 11e – ) Chlorine atom (Cl) (17p + ; 18n 0 ; 17e – ) Sodium ion (Na + )Chloride ion (Cl – ) Sodium chloride (NaCl) +– (a) Sodium gains stability by losing one electron, and chlorine becomes stable by gaining one electron. (b) After electron transfer, the oppositely charged ions formed attract each other.

Formation of an Ionic Bond Ionic compounds form crystals instead of individual molecules NaCl (sodium chloride)

Copyright © 2010 Pearson Education, Inc. Figure 2.6c CI – Na + (c) Large numbers of Na + and Cl – ions associate to form salt (NaCl) crystals.

Covalent Bonds Formed by sharing of two or more valence shell electrons Allows each atom to fill its valence shell at least part of the time

Copyright © 2010 Pearson Education, Inc. Figure 2.7a + Hydrogen atoms Carbon atom Molecule of methane gas (CH 4 ) Structural formula shows single bonds. (a) Formation of four single covalent bonds: carbon shares four electron pairs with four hydrogen atoms. or Resulting moleculesReacting atoms

Copyright © 2010 Pearson Education, Inc. Figure 2.7b or Oxygen atom Oxygen atom Molecule of oxygen gas (O 2 ) Structural formula shows double bond. (b) Formation of a double covalent bond: Two oxygen atoms share two electron pairs. Resulting moleculesReacting atoms +

Copyright © 2010 Pearson Education, Inc. Figure 2.7c + or Nitrogen atom Nitrogen atom Molecule of nitrogen gas (N 2 ) Structural formula shows triple bond. (c) Formation of a triple covalent bond: Two nitrogen atoms share three electron pairs. Resulting moleculesReacting atoms

Covalent Bonds Sharing of electrons may be equal or unequal Equal sharing produces electrically balanced nonpolar molecules CO 2

Copyright © 2010 Pearson Education, Inc. Figure 2.8a

Covalent Bonds Unequal sharing by atoms with different electron- attracting abilities produces polar molecules H 2 O Atoms with six or seven valence shell electrons are electronegative, e.g., oxygen Atoms with one or two valence shell electrons are electropositive, e.g., sodium

Copyright © 2010 Pearson Education, Inc. Figure 2.8b

Copyright © 2010 Pearson Education, Inc. Figure 2.9

Hydrogen Bonds Attractive force between electropositive hydrogen of one molecule and an electronegative atom of another molecule Common between dipoles such as water Also act as intramolecular bonds, holding a large molecule in a three-dimensional shape PLAY Animation: Hydrogen Bonds

Copyright © 2010 Pearson Education, Inc. (a) The slightly positive ends (  + ) of the water molecules become aligned with the slightly negative ends (  – ) of other water molecules. ++ –– –– –– –– –– ++ ++ ++ ++ ++ Hydrogen bond (indicated by dotted line) Figure 2.10a

Copyright © 2010 Pearson Education, Inc. Figure 2.10b (b) A water strider can walk on a pond because of the high surface tension of water, a result of the combined strength of its hydrogen bonds.

Chemical Reactions Occur when chemical bonds are formed, rearranged, or broken Represented as chemical equations Chemical equations contain: Molecular formula for each reactant and product Relative amounts of reactants and products, which should balance

Examples of Chemical Equations H + H  H 2 (hydrogen gas) 4H + C  CH 4 (methane) (reactants)(product)

Patterns of Chemical Reactions Synthesis (combination) reactions Synthesis (combination) reactions Decomposition reactions Decomposition reactions Exchange reactions Exchange reactions

Synthesis Reactions A + B  AB Always involve bond formation Anabolic Anabolic

Copyright © 2010 Pearson Education, Inc. Figure 2.11a Example Amino acids are joined together to form a protein molecule. (a) Synthesis reactions Smaller particles are bonded together to form larger, more complex molecules. Amino acid molecules Protein molecule

Decomposition Reactions AB  A + B Reverse synthesis reactions Involve breaking of bonds Catabolic

Copyright © 2010 Pearson Education, Inc. Figure 2.11b Example Glycogen is broken down to release glucose units. Bonds are broken in larger molecules, resulting in smaller, less complex molecules. (b) Decomposition reactions Glucose molecules Glycogen

Exchange Reactions AB + C  AC + B Also called displacement reactions Bonds are both made and broken

Copyright © 2010 Pearson Education, Inc. Figure 2.11c Example ATP transfers its terminal phosphate group to glucose to form glucose-phosphate. Bonds are both made and broken (also called displacement reactions). (c) Exchange reactions GlucoseAdenosine triphosphate (ATP) Adenosine diphosphate (ADP) Glucose phosphate + +

Oxidation-Reduction (Redox) Reactions Decomposition reactions: Reactions in which fuel is broken down for energy Also called exchange reactions because electrons are exchanged or shared differently Electron donors lose electrons and are oxidized Electron acceptors receive electrons and become reduced

Chemical Reactions All chemical reactions are either exergonic or endergonic Exergonic reactions—release energy Catabolic reactions Endergonic reactions—products contain more potential energy than did reactants Anabolic reactions

Chemical Reactions All chemical reactions are theoretically reversible A + B  AB AB  A + B Chemical equilibrium occurs if neither a forward nor reverse reaction is dominant Many biological reactions are essentially irreversible due to Many biological reactions are essentially irreversible due to Energy requirements Energy requirements Removal of products Removal of products

Rate of Chemical Reactions Rate of reaction is influenced by:  temperature   rate  particle size   rate  concentration of reactant   rate Catalysts:  rate without being chemically changed Enzymes are biological catalysts