© Cancer Research UK 2005 Registered charity number Table One: Numbers and rates of new cases, non-Hodgkin lymphoma, UK, 2006 EnglandWalesScotlandN.IrelandUK Cases Males4, ,658 Females4, ,911 Persons8, ,569 Crude rate per 100,000 population Males Females Persons Age-standardised rate (European) per 100,000 population Males % CI Females % CI Persons % CI

© Cancer Research UK 2005 Registered charity number Figure One: Numbers of new cases and age specific incidence rates, by sex, non-Hodgkin lymphoma, UK 2006

© Cancer Research UK 2005 Registered charity number Figure Two: Age-standardised incidence and mortality rates for NHL in males by region of the world, 2002 estimates

© Cancer Research UK 2005 Registered charity number Figure Three: Age-standardised incidence rates, non-Hodgkin lymphoma, by sex, EU, 2002

© Cancer Research UK 2005 Registered charity number Table Two: WHO Classification of NHL B-cell Mature B-cell lymphomas Precursor B-cell lymphoma Small lymphocytic lymphoma Lymphoplasmacytic lymphoma Splenic marginal zone lymphoma Hairy cell leukaemia Plasma cell neoplasms Extranodal marginal zone B-cell lymphoma of mucosa- associated lymphoid tissue (MALT lymphoma) Nodal marginal zone B-cell lymphoma Follicular lymphoma (grades 1, 2, 3a and 3b) Diffuse follicle centre lymphoma Mantle cell lymphoma Diffuse large B-cell lymphoma Mediastinal (thymic) large B-cell lymphoma Intravascular large B-cell lymphoma Primary effusion lymphoma Burkitt lymphoma B-cell proliferations of uncertain malignant potential Lymphomatoid granulomatosis Post-transplant lymphoproliferative disorder, polymorphic

© Cancer Research UK 2005 Registered charity number Table Two (continued): WHO Classification of NHL T-cell and NK-cell Precursor T- and NK-cell lymphomas Precursor T lymphoblastic lymphoma Blastic NK-cell lymphoma Mature T-cell and NK-cell lymphomas T-cell prolymphocytic leukaemia T-cell large granular lymphocytic leukaemia Aggressive NK-cell leukaemia Adult T-cell lymphoma/leukaemia Extranodal NK-/T-cell lymphoma, nasal type Enteropathy-type T-cell lymphoma Hepatosplenic T-cell lymphoma Subcutaneous panniculitis-like T-cell lymphoma Mycosis fungoides Peripheral T-cell lymphoma unspecified Angioimmunoblastic T-cell lymphoma Anaplastic large cell lymphoma

© Cancer Research UK 2005 Registered charity number Figure Four: Age standardised (European) incidence rates, non-Hodgkin lymphoma cancer, by sex, GB,

© Cancer Research UK 2005 Registered charity number Figure Five: Percentage change in age-specific incidence of NHL from 1975, persons, Great Britain

© Cancer Research UK 2005 Registered charity number Table Three: Examples of cytogenetic/molecular abnormalities in NHL

© Cancer Research UK 2005 Registered charity number Table Four: Primary extranodal sites for NHL

© Cancer Research UK 2005 Registered charity number Table Five: Number of deaths and mortality rates, NHL, UK by country, 2007 EnglandWalesScotlandN.IrelandUK Deaths Males2, ,443 Females1, ,090 Persons3, ,533 Crude rate per 100,000 population Males Females Persons Age-standardised rate (European) per 100,000 population Males CI 95% Females CI 95% Persons CI 95%

© Cancer Research UK 2005 Registered charity number Figure Six: Number of deaths and mortality rates, NHL, UK by country, 2007

© Cancer Research UK 2005 Registered charity number Figure Seven: One-, Five- and Ten-year relative survival for adults diagnosed with NHL in England and Wales during and followed up to the end of 2001 and period survival estimates for patients alive with a diagnosis at some point during

© Cancer Research UK 2005 Registered charity number Figure Eight: Age-standardised relative five-year survival for men diagnosed with NHL , European countries